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Central Skull Base Trigeminal Schwannoma
Daniel E. Meltzer, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Trigeminal schwannoma (TS)
            • Synonyms

              • Giant TS, "dumbbell" TS

            IMAGING

            • General Features

              • Imaging Recommendations

                • CT Findings

                  • MR Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Abou-Al-Shaar H et al: Surgical management of multifocal trigeminal schwannomas. Oper Neurosurg (Hagerstown). ePub, 2020
                                      2. Li M et al: Trigeminal schwannoma: a single-center experience with 43 cases and review of literature. Br J Neurosurg. 1-8, 2020
                                      3. Nguyen DA et al: Successful endoscopic endonasal surgery for very huge trigeminal schwannomas in nasopharynx. Br J Neurosurg. 1-4, 2020
                                      4. Wang X et al: Trigeminal schwannomas in middle fossa could breach into subdural space: report of 4 cases and review of literature. World Neurosurg. 127:e534-41, 2019
                                      5. Aboukais R et al: Management of multiple tumors in neurofibromatosis type 2 patients. Neurochirurgie. 64(5):364-9, 2015
                                      6. Agarwal A: Intracranial trigeminal schwannoma. Neuroradiol J. 28(1):36-41, 2015
                                      7. Gasco J et al: Dissemination of prostate adenocarcinoma to the skull base mimicking giant trigeminal schwannoma: anatomic relevance of the extradural neural axis component. Skull Base. 19(6):425-30, 2009
                                      8. Zhang L et al: Trigeminal schwannomas: a report of 42 cases and review of the relevant surgical approaches. Clin Neurol Neurosurg. 111(3):261-9, 2009
                                      9. Sharma BS et al: Trigeminal schwannomas: experience with 68 cases. J Clin Neurosci. 15(7):738-43, 2008
                                      10. Kouyialis AT et al: Giant dumbbell-shaped middle cranial fossa trigeminal schwannoma with extension to the infratemporal and posterior fossae. Acta Neurochir (Wien). 149(9):959-63; discussion 964, 2007
                                      11. Pamir MN et al: Surgical treatment of trigeminal schwannomas. Neurosurg Rev. 30(4):329-37; discussion 337, 2007
                                      12. Zhou LF et al: Surgical treatment of dumbbell-shaped neurinomas: report of an experience with 57 cases in a single hospital. Surg Neurol. 68(6):594-602, 2007
                                      13. Abdel Aziz KM et al: Primary lymphoma of Meckel's cave mimicking trigeminal schwannoma: case report. Neurosurgery. 44(4):859-62; discussion 862-3, 1999
                                      14. Yoshida K et al: Trigeminal neurinomas extending into multiple fossae: surgical methods and review of the literature. J Neurosurg. 91(2):202-11, 1999
                                      15. Turgut M et al: Giant schwannoma of the trigeminal nerve misdiagnosed as maxillary sinusitis. A case report. S Afr J Surg. 35(3):131-3, 1997
                                      16. Samii M et al: Surgical treatment of trigeminal schwannomas. J Neurosurg. 82(5):711-8, 1995
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Pathology

                                              • Diagnostic Checklist

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Trigeminal schwannoma (TS)
                                                • Synonyms

                                                  • Giant TS, "dumbbell" TS

                                                IMAGING

                                                • General Features

                                                  • Imaging Recommendations

                                                    • CT Findings

                                                      • MR Findings

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Gross Pathologic & Surgical Features

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      DIAGNOSTIC CHECKLIST

                                                                      • Consider

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Abou-Al-Shaar H et al: Surgical management of multifocal trigeminal schwannomas. Oper Neurosurg (Hagerstown). ePub, 2020
                                                                          2. Li M et al: Trigeminal schwannoma: a single-center experience with 43 cases and review of literature. Br J Neurosurg. 1-8, 2020
                                                                          3. Nguyen DA et al: Successful endoscopic endonasal surgery for very huge trigeminal schwannomas in nasopharynx. Br J Neurosurg. 1-4, 2020
                                                                          4. Wang X et al: Trigeminal schwannomas in middle fossa could breach into subdural space: report of 4 cases and review of literature. World Neurosurg. 127:e534-41, 2019
                                                                          5. Aboukais R et al: Management of multiple tumors in neurofibromatosis type 2 patients. Neurochirurgie. 64(5):364-9, 2015
                                                                          6. Agarwal A: Intracranial trigeminal schwannoma. Neuroradiol J. 28(1):36-41, 2015
                                                                          7. Gasco J et al: Dissemination of prostate adenocarcinoma to the skull base mimicking giant trigeminal schwannoma: anatomic relevance of the extradural neural axis component. Skull Base. 19(6):425-30, 2009
                                                                          8. Zhang L et al: Trigeminal schwannomas: a report of 42 cases and review of the relevant surgical approaches. Clin Neurol Neurosurg. 111(3):261-9, 2009
                                                                          9. Sharma BS et al: Trigeminal schwannomas: experience with 68 cases. J Clin Neurosci. 15(7):738-43, 2008
                                                                          10. Kouyialis AT et al: Giant dumbbell-shaped middle cranial fossa trigeminal schwannoma with extension to the infratemporal and posterior fossae. Acta Neurochir (Wien). 149(9):959-63; discussion 964, 2007
                                                                          11. Pamir MN et al: Surgical treatment of trigeminal schwannomas. Neurosurg Rev. 30(4):329-37; discussion 337, 2007
                                                                          12. Zhou LF et al: Surgical treatment of dumbbell-shaped neurinomas: report of an experience with 57 cases in a single hospital. Surg Neurol. 68(6):594-602, 2007
                                                                          13. Abdel Aziz KM et al: Primary lymphoma of Meckel's cave mimicking trigeminal schwannoma: case report. Neurosurgery. 44(4):859-62; discussion 862-3, 1999
                                                                          14. Yoshida K et al: Trigeminal neurinomas extending into multiple fossae: surgical methods and review of the literature. J Neurosurg. 91(2):202-11, 1999
                                                                          15. Turgut M et al: Giant schwannoma of the trigeminal nerve misdiagnosed as maxillary sinusitis. A case report. S Afr J Surg. 35(3):131-3, 1997
                                                                          16. Samii M et al: Surgical treatment of trigeminal schwannomas. J Neurosurg. 82(5):711-8, 1995