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Cerebellar Liponeurocytoma
Karen L. Salzman, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Cerebellar liponeurocytoma (CLN)
            • Synonyms

              • Lipomatous medulloblastoma (old term)
            • Definitions

              • Rare cerebellar parenchymal neoplasm of adults
                • Consistent neuronal, variable astrocytic, and lipomatous elements

            IMAGING

            • General Features

              • Imaging Recommendations

                • CT Findings

                  • MR Findings

                    • PET

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Deora H et al: Cerebellar liponeurocytoma: A rare fatty tumor and its literature review. J Neurosci Rural Pract. 10(2):360-3, 2019
                                        2. Gembruch O et al: Liponeurocytoma: Systematic review of a rare entity. World Neurosurg. 120:214-33, 2018
                                        3. Hamzaoglu V et al: Clinical course of the untreated calcified big cerebellar liponeurocytoma. J Surg Case Rep. 2018(11):rjy316, 2018
                                        4. Khatri D et al: Cerebellar liponeurocytoma: The dilemma of multifocality. World Neurosurg. 120:131-7, 2018
                                        5. Hermann B et al: Cerebellar liponeurocytoma with atypical histological features - a rare example of a glioneuronal tumor. Folia Neuropathol. 55(3):227-34, 2017
                                        6. Louis DN et al: The WHO Classification of Tumours of the Nervous System. Lyon, France: IARC, 161-3, 2016
                                        7. Takami H et al: Findings from positron emission tomography and genetic analyses for cerebellar liponeurocytoma. Brain Tumor Pathol. ePub, 2014
                                        8. Guan JT et al: Magnetic resonance imaging of cerebellar liponeurocytoma. A case report and review of the literature. Neuroradiol J. 25(3):331-6, 2012
                                        9. Nishimoto T et al: Cerebellar liponeurocytoma. Arch Pathol Lab Med. 136(8):965-9, 2012
                                        10. Chakraborti S et al: Supratentorial and cerebellar liponeurocytomas: report of four cases with review of literature. J Neurooncol. 103(1):121-7, 2011
                                        11. Patel N et al: Cerebellar liponeurocytoma. Can J Surg. 52(4):E117-9, 2009
                                        12. Brat DJ et al: Surgical neuropathology update: a review of changes introduced by the WHO classification of tumours of the central nervous system, 4th edition. Arch Pathol Lab Med. 132(6):993-1007, 2008
                                        13. Aker FV et al: Cerebellar liponeurocytoma/lipidized medulloblastoma. J Neurooncol. 71(1):53-9, 2005
                                        14. Owler BK et al: Cerebellar liponeurocytoma. J Clin Neurosci. 12(3):326-9, 2005
                                        15. Horstmann S et al: Genetic and expression profiles of cerebellar liponeurocytomas. Brain Pathol. 14(3):281-9, 2004
                                        16. Akhaddar A et al: Cerebellar liponeurocytoma (lipomatous medulloblastoma). J Neuroradiol. 30(2):121-6, 2003
                                        17. Fung KM et al: Cerebellar central liponeurocytoma. Ultrastruct Pathol. 27(2):109-14, 2003
                                        18. Montagna N et al: Cerebellar liponeurocytoma: a newly recognized clinico-pathological entity. Arq Neuropsiquiatr. 60(3-B):725-9, 2002
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Cerebellar liponeurocytoma (CLN)
                                                  • Synonyms

                                                    • Lipomatous medulloblastoma (old term)
                                                  • Definitions

                                                    • Rare cerebellar parenchymal neoplasm of adults
                                                      • Consistent neuronal, variable astrocytic, and lipomatous elements

                                                  IMAGING

                                                  • General Features

                                                    • Imaging Recommendations

                                                      • CT Findings

                                                        • MR Findings

                                                          • PET

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Staging, Grading, & Classification

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Deora H et al: Cerebellar liponeurocytoma: A rare fatty tumor and its literature review. J Neurosci Rural Pract. 10(2):360-3, 2019
                                                                              2. Gembruch O et al: Liponeurocytoma: Systematic review of a rare entity. World Neurosurg. 120:214-33, 2018
                                                                              3. Hamzaoglu V et al: Clinical course of the untreated calcified big cerebellar liponeurocytoma. J Surg Case Rep. 2018(11):rjy316, 2018
                                                                              4. Khatri D et al: Cerebellar liponeurocytoma: The dilemma of multifocality. World Neurosurg. 120:131-7, 2018
                                                                              5. Hermann B et al: Cerebellar liponeurocytoma with atypical histological features - a rare example of a glioneuronal tumor. Folia Neuropathol. 55(3):227-34, 2017
                                                                              6. Louis DN et al: The WHO Classification of Tumours of the Nervous System. Lyon, France: IARC, 161-3, 2016
                                                                              7. Takami H et al: Findings from positron emission tomography and genetic analyses for cerebellar liponeurocytoma. Brain Tumor Pathol. ePub, 2014
                                                                              8. Guan JT et al: Magnetic resonance imaging of cerebellar liponeurocytoma. A case report and review of the literature. Neuroradiol J. 25(3):331-6, 2012
                                                                              9. Nishimoto T et al: Cerebellar liponeurocytoma. Arch Pathol Lab Med. 136(8):965-9, 2012
                                                                              10. Chakraborti S et al: Supratentorial and cerebellar liponeurocytomas: report of four cases with review of literature. J Neurooncol. 103(1):121-7, 2011
                                                                              11. Patel N et al: Cerebellar liponeurocytoma. Can J Surg. 52(4):E117-9, 2009
                                                                              12. Brat DJ et al: Surgical neuropathology update: a review of changes introduced by the WHO classification of tumours of the central nervous system, 4th edition. Arch Pathol Lab Med. 132(6):993-1007, 2008
                                                                              13. Aker FV et al: Cerebellar liponeurocytoma/lipidized medulloblastoma. J Neurooncol. 71(1):53-9, 2005
                                                                              14. Owler BK et al: Cerebellar liponeurocytoma. J Clin Neurosci. 12(3):326-9, 2005
                                                                              15. Horstmann S et al: Genetic and expression profiles of cerebellar liponeurocytomas. Brain Pathol. 14(3):281-9, 2004
                                                                              16. Akhaddar A et al: Cerebellar liponeurocytoma (lipomatous medulloblastoma). J Neuroradiol. 30(2):121-6, 2003
                                                                              17. Fung KM et al: Cerebellar central liponeurocytoma. Ultrastruct Pathol. 27(2):109-14, 2003
                                                                              18. Montagna N et al: Cerebellar liponeurocytoma: a newly recognized clinico-pathological entity. Arq Neuropsiquiatr. 60(3-B):725-9, 2002