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Cerebral Infarction, Top of Basilar
Edward P. Quigley, III, MD, PhD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Top of basilar (TOB) syndrome
          • Definitions

            • Infarction of rostral brainstem and cerebral hemispheres supplied by distal basilar artery
            • Clinically recognizable syndrome characterized by visual, oculomotor, and behavioral abnormalities, often without significant motor dysfunction

          IMAGING

          • Imaging Anatomy

            • General Features

              • CT Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      CLINICAL ISSUES

                      • Presentation

                        • Natural History & Prognosis

                          • Treatment

                            DIAGNOSTIC CHECKLIST

                            • Consider

                              • Image Interpretation Pearls

                                Selected References

                                1. Govaert P et al: Top of the basilar artery embolic stroke and neonatal myoclonus. Dev Med Child Neurol. 51(4):324-7, 2009
                                2. Kato Y et al: Takotsubo cardiomyopathy associated with top of the basilar artery syndrome. J Neurol. 256(1):141-2, 2009
                                3. Tilikete C et al: Ocular motor syndromes of the brainstem and cerebellum. Curr Opin Neurol. 21(1):22-8, 2008
                                4. Spengos K et al: Bilateral paramedian midbrain infarct: an uncommon variant of the "top of the basilar" syndrome. J Neurol Neurosurg Psychiatry. 76(5):742-3, 2005
                                5. Ameridou I et al: Bithalamic infarcts: embolism of the top of basilar artery or deep cerebral venous thrombosis? Clin Neurol Neurosurg. 106(4):345-7, 2004
                                6. Silverman IE et al: Cerebellar top-of-the-basilar syndrome. Clin Neurol Neurosurg. 100(4):296-8, 1998
                                Related Anatomy
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                                Related Differential Diagnoses
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                                References
                                Tables

                                Tables

                                KEY FACTS

                                • Terminology

                                  • Imaging

                                    • Top Differential Diagnoses

                                      • Clinical Issues

                                        TERMINOLOGY

                                        • Abbreviations

                                          • Top of basilar (TOB) syndrome
                                        • Definitions

                                          • Infarction of rostral brainstem and cerebral hemispheres supplied by distal basilar artery
                                          • Clinically recognizable syndrome characterized by visual, oculomotor, and behavioral abnormalities, often without significant motor dysfunction

                                        IMAGING

                                        • Imaging Anatomy

                                          • General Features

                                            • CT Findings

                                              • MR Findings

                                                • Imaging Recommendations

                                                  DIFFERENTIAL DIAGNOSIS

                                                    CLINICAL ISSUES

                                                    • Presentation

                                                      • Natural History & Prognosis

                                                        • Treatment

                                                          DIAGNOSTIC CHECKLIST

                                                          • Consider

                                                            • Image Interpretation Pearls

                                                              Selected References

                                                              1. Govaert P et al: Top of the basilar artery embolic stroke and neonatal myoclonus. Dev Med Child Neurol. 51(4):324-7, 2009
                                                              2. Kato Y et al: Takotsubo cardiomyopathy associated with top of the basilar artery syndrome. J Neurol. 256(1):141-2, 2009
                                                              3. Tilikete C et al: Ocular motor syndromes of the brainstem and cerebellum. Curr Opin Neurol. 21(1):22-8, 2008
                                                              4. Spengos K et al: Bilateral paramedian midbrain infarct: an uncommon variant of the "top of the basilar" syndrome. J Neurol Neurosurg Psychiatry. 76(5):742-3, 2005
                                                              5. Ameridou I et al: Bithalamic infarcts: embolism of the top of basilar artery or deep cerebral venous thrombosis? Clin Neurol Neurosurg. 106(4):345-7, 2004
                                                              6. Silverman IE et al: Cerebellar top-of-the-basilar syndrome. Clin Neurol Neurosurg. 100(4):296-8, 1998