IBD: Crohn disease (CD) and ulcerative colitis (UC)
Chronic conditions with peak onset in adolescence and early adult life
CD: Transmural process affecting any portion of GI tract with predilection for terminal ileum
Includes inflammatory, penetrating, and fibrostenotic phenotypes
Penetrating disease extends beyond bowel serosa into mesenterium
Fibrostenotic disease is characterized by luminal narrowing of bowel, frequently associated with bowel obstruction
UC: Characterized by superficial mucosal inflammation of colon that extends proximally from anal verge in contiguous manner
Comb sign: Represents filling of prominent straight intestinal arterial branches in mesenteric arcade suggesting active disease
CLINICAL IMPLICATIONS
Clinical Importance
Clinical Considerations
Contributions of US/CEUS
CEUS TECHNIQUE
Bowel Imaging
IMAGING
US/CEUS Findings
Determination of Disease Activity
Subjective Assessment
Objective Assessment
Monitoring Response to Therapy
Differentiation of Strictures
Selected References
Maconi G et al: EFSUMB Recommendations and clinical guidelines for intestinal ultrasound (GIUS) in inflammatory bowel diseases. Ultraschall Med. 39(3):304-317, 2018
Medellin A et al: Role of contrast-enhanced ultrasound in evaluation of the bowel. Abdom Radiol (NY). 43(4):918-933, 2018
Pecere S et al: Usefulness of contrast-enhanced ultrasound (CEUS) in inflammatory bowel disease (IBD). Dig Liver Dis. 50(8):761-767, 2018
Mocci G et al: SICUS and CEUS imaging in Crohn's disease: an update. J Ultrasound. 20(1):1-9, 2017
Medellin-Kowalewski A et al: Quantitative contrast-enhanced ultrasound parameters in Crohn disease: Their role in disease activity determination with ultrasound. AJR Am J Roentgenol. 206(1):64-73, 2016
Serafin Z et al: Contrast-enhanced ultrasound for detection of Crohn's disease activity: Systematic review and meta-analysis. J Crohns Colitis. 10(3):354-62, 2016
Braden B et al: Diagnostic value and clinical utility of contrast enhanced ultrasound in intestinal diseases. Dig Liver Dis. 42(10):667-74, 2010
Ripollés T et al: Crohn disease: correlation of findings at contrast-enhanced US with severity at endoscopy. Radiology. 253(1):241-8, 2009
Satsangi J et al: The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut. 55(6):749-53, 2006
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
GENERAL DISCUSSION
IMAGING
TERMINOLOGY
Abbreviations
Inflammatory bowel disease (IBD)
Definitions
IBD: Crohn disease (CD) and ulcerative colitis (UC)
Chronic conditions with peak onset in adolescence and early adult life
CD: Transmural process affecting any portion of GI tract with predilection for terminal ileum
Includes inflammatory, penetrating, and fibrostenotic phenotypes
Penetrating disease extends beyond bowel serosa into mesenterium
Fibrostenotic disease is characterized by luminal narrowing of bowel, frequently associated with bowel obstruction
UC: Characterized by superficial mucosal inflammation of colon that extends proximally from anal verge in contiguous manner
Comb sign: Represents filling of prominent straight intestinal arterial branches in mesenteric arcade suggesting active disease
CLINICAL IMPLICATIONS
Clinical Importance
Clinical Considerations
Contributions of US/CEUS
CEUS TECHNIQUE
Bowel Imaging
IMAGING
US/CEUS Findings
Determination of Disease Activity
Subjective Assessment
Objective Assessment
Monitoring Response to Therapy
Differentiation of Strictures
Selected References
Maconi G et al: EFSUMB Recommendations and clinical guidelines for intestinal ultrasound (GIUS) in inflammatory bowel diseases. Ultraschall Med. 39(3):304-317, 2018
Medellin A et al: Role of contrast-enhanced ultrasound in evaluation of the bowel. Abdom Radiol (NY). 43(4):918-933, 2018
Pecere S et al: Usefulness of contrast-enhanced ultrasound (CEUS) in inflammatory bowel disease (IBD). Dig Liver Dis. 50(8):761-767, 2018
Mocci G et al: SICUS and CEUS imaging in Crohn's disease: an update. J Ultrasound. 20(1):1-9, 2017
Medellin-Kowalewski A et al: Quantitative contrast-enhanced ultrasound parameters in Crohn disease: Their role in disease activity determination with ultrasound. AJR Am J Roentgenol. 206(1):64-73, 2016
Serafin Z et al: Contrast-enhanced ultrasound for detection of Crohn's disease activity: Systematic review and meta-analysis. J Crohns Colitis. 10(3):354-62, 2016
Braden B et al: Diagnostic value and clinical utility of contrast enhanced ultrasound in intestinal diseases. Dig Liver Dis. 42(10):667-74, 2010
Ripollés T et al: Crohn disease: correlation of findings at contrast-enhanced US with severity at endoscopy. Radiology. 253(1):241-8, 2009
Satsangi J et al: The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut. 55(6):749-53, 2006
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