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Ultrasound
Diagnosis
Liver
Focal Solid Masses
CEUS Liver: Focal Lesions in High-Risk Patients
CEUS Liver: Focal Lesions in High-Risk Patients
Stephanie R. Wilson, MD; Benjamin A. Caine, BMSc; Alexandra Medellin, MD
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KEY FACTS

  • Clinical Implications

    • IMAGING

      CLINICAL IMPLICATIONS

      • Demographics and Prevalence

        • Clinical Considerations

          PATHOLOGY

          • Hepatocellular Carcinoma

            • Intrahepatic Cholangiocarcinoma

              IMAGING

              • Overview

                • Hepatocellular Carcinoma

                  • Intrahepatic Cholangiocarcinoma

                    DIFFERENTIAL DIAGNOSIS

                    • Overview

                      Selected References

                      1. Yang D et al: Perfusion characteristics of hepatocellular carcinoma at contrast-enhanced ultrasound: influence of the cellular differentiation, the tumor size and the underlying hepatic condition. Sci Rep. 8(1):4713, 2018
                      2. Burrowes DP et al: Contrast-enhanced US approach to the diagnosis of focal liver masses. Radiographics. 37(5):1388-1400, 2017
                      3. Durot I et al: Contrast-enhanced ultrasound of malignant liver lesions. Abdom Radiol (NY). 43(4):819-847, 2018
                      4. Jo PC et al: Integration of contrast-enhanced us into a multimodality approach to imaging of nodules in a cirrhotic liver: how I do it. Radiology. 282(2):317-331, 2017
                      5. Vijgen S et al: Pathology of intrahepatic cholangiocarcinoma. Hepatobiliary Surg Nutr. 6(1):22-34, 2017
                      6. Miller ZA et al: Screening for hepatocellular carcinoma in high-risk populations. Clin Imaging. 40(2):311-4, 2016
                      7. Li R et al: Detailed analysis of temporal features on contrast enhanced ultrasound may help differentiate intrahepatic cholangiocarcinoma from hepatocellular carcinoma in cirrhosis. PLoS One. 9(5):e98612, 2014
                      8. Bhayana D et al: Hypervascular liver masses on contrast-enhanced ultrasound: the importance of washout. AJR Am J Roentgenol. 194(4):977-83, 2010
                      9. Chen LD et al: Intrahepatic cholangiocarcinoma and hepatocellular carcinoma: differential diagnosis with contrast-enhanced ultrasound. Eur Radiol. 20(3):743-53, 2010
                      10. Vilana R et al: Intrahepatic peripheral cholangiocarcinoma in cirrhosis patients may display a vascular pattern similar to hepatocellular carcinoma on contrast-enhanced ultrasound. Hepatology. 51(6):2020-9, 2010
                      11. Jang HJ et al: Small nodules (1-2 cm) in liver cirrhosis: characterization with contrast-enhanced ultrasound. Eur J Radiol. 72(3):418-24, 2009
                      12. Jang HJ et al: Enhancement patterns of hepatocellular carcinoma at contrast-enhanced US: comparison with histologic differentiation. Radiology. 244(3):898-906, 2007
                      13. van den Bos IC et al: Stepwise carcinogenesis of hepatocellular carcinoma in the cirrhotic liver: demonstration on serial MR imaging. J Magn Reson Imaging. 24(5):1071-80, 2006
                      Related Anatomy
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                      Related Differential Diagnoses
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                      References
                      Tables

                      Tables

                      KEY FACTS

                      • Clinical Implications

                        • IMAGING

                          CLINICAL IMPLICATIONS

                          • Demographics and Prevalence

                            • Clinical Considerations

                              PATHOLOGY

                              • Hepatocellular Carcinoma

                                • Intrahepatic Cholangiocarcinoma

                                  IMAGING

                                  • Overview

                                    • Hepatocellular Carcinoma

                                      • Intrahepatic Cholangiocarcinoma

                                        DIFFERENTIAL DIAGNOSIS

                                        • Overview

                                          Selected References

                                          1. Yang D et al: Perfusion characteristics of hepatocellular carcinoma at contrast-enhanced ultrasound: influence of the cellular differentiation, the tumor size and the underlying hepatic condition. Sci Rep. 8(1):4713, 2018
                                          2. Burrowes DP et al: Contrast-enhanced US approach to the diagnosis of focal liver masses. Radiographics. 37(5):1388-1400, 2017
                                          3. Durot I et al: Contrast-enhanced ultrasound of malignant liver lesions. Abdom Radiol (NY). 43(4):819-847, 2018
                                          4. Jo PC et al: Integration of contrast-enhanced us into a multimodality approach to imaging of nodules in a cirrhotic liver: how I do it. Radiology. 282(2):317-331, 2017
                                          5. Vijgen S et al: Pathology of intrahepatic cholangiocarcinoma. Hepatobiliary Surg Nutr. 6(1):22-34, 2017
                                          6. Miller ZA et al: Screening for hepatocellular carcinoma in high-risk populations. Clin Imaging. 40(2):311-4, 2016
                                          7. Li R et al: Detailed analysis of temporal features on contrast enhanced ultrasound may help differentiate intrahepatic cholangiocarcinoma from hepatocellular carcinoma in cirrhosis. PLoS One. 9(5):e98612, 2014
                                          8. Bhayana D et al: Hypervascular liver masses on contrast-enhanced ultrasound: the importance of washout. AJR Am J Roentgenol. 194(4):977-83, 2010
                                          9. Chen LD et al: Intrahepatic cholangiocarcinoma and hepatocellular carcinoma: differential diagnosis with contrast-enhanced ultrasound. Eur Radiol. 20(3):743-53, 2010
                                          10. Vilana R et al: Intrahepatic peripheral cholangiocarcinoma in cirrhosis patients may display a vascular pattern similar to hepatocellular carcinoma on contrast-enhanced ultrasound. Hepatology. 51(6):2020-9, 2010
                                          11. Jang HJ et al: Small nodules (1-2 cm) in liver cirrhosis: characterization with contrast-enhanced ultrasound. Eur J Radiol. 72(3):418-24, 2009
                                          12. Jang HJ et al: Enhancement patterns of hepatocellular carcinoma at contrast-enhanced US: comparison with histologic differentiation. Radiology. 244(3):898-906, 2007
                                          13. van den Bos IC et al: Stepwise carcinogenesis of hepatocellular carcinoma in the cirrhotic liver: demonstration on serial MR imaging. J Magn Reson Imaging. 24(5):1071-80, 2006