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CEUS Spleen: Benign Lesions
Julia Zavariz, MD; Annamaria Deganello, MD; Paul S. Sidhu, BSc, MBBS, MRCP, FRCR, DTM&H
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KEY FACTS

  • CEUS TECHNIQUE

    • IMAGING

      CLINICAL IMPLICATIONS

      • Splenic Cysts

        • Splenic Abscess

          • Sarcoidosis

            • Splenic Infarction

              • Splenic Hemangioma

                • Splenic Hamartoma

                  • Splenic Lymphangioma

                    • Accessory Spleens and Postsplenectomy Splenosis (Splenunculi)

                      CEUS TECHNIQUE

                      • CEUS Protocol Advice

                        Imaging

                        • Splenic Hamartoma

                          • Splenic Infarction

                            • Splenic Cyst

                              • Splenic Abscess

                                • Sarcoidosis

                                  • Splenic Hemangioma

                                    • Splenic Lymphangioma

                                      • Accessory Spleens and Postsplenectomy Splenosis (Splenunculi)

                                        Selected References

                                        1. Sidhu PS et al: The EFSUMB Guidelines and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound (CEUS) in Non-Hepatic Applications: Update 2017 (Short Version). Ultraschall Med. 39(2):154-180, 2018
                                        2. Zavariz JD et al: Common and uncommon features of focal splenic lesions on contrast-enhanced ultrasound: a pictorial review. Radiol Bras. 50(6):395-404, 2017
                                        3. Knieling F et al: Spectrum, applicability and diagnostic capacity of contrast-enhanced ultrasound in pediatric patients and young adults after intravenous application - a retrospective trial. Ultraschall Med. 37(6):619-626, 2016
                                        4. Omar A et al: Contrast-enhanced ultrasound of the spleen. Ultrasound. 24(1):41-9, 2016
                                        5. Roman A et al: Splenic cystic lymphangioma with atypical ultrasound findings. J Med Ultrason (2001). 43(1):99-105, 2016
                                        6. Tana C et al: Hepatosplenic sarcoidosis: contrast-enhanced ultrasound findings and implications for clinical practice. Biomed Res Int. 2014:926203, 2014
                                        7. Caremani M et al: Focal splenic lesions: US findings. J Ultrasound. 16(2):65-74, 2013
                                        8. Grzelak P et al: Diagnostic potential of contrast-enhanced ultrasound (CEUS) in the assessment of spleen and liver granulomas in the course of sarcoidosis. Pneumonol Alergol Pol. 81(5):424-8, 2013
                                        9. Grzelak P et al: Use of contrast-enhanced ultrasonography in hepatosplenic sarcoidosis: Report of 2 cases. Pol J Radiol. 77(3):60-3, 2012
                                        10. Yu X et al: Real-time contrast-enhanced ultrasound in diagnosing of focal spleen lesions. Eur J Radiol. 81(3):430-6, 2012
                                        11. Wells IT et al: Differentiating a benign splenic lesion from an isolated metastasis with contrast-enhanced sonography. J Ultrasound Med. 29(9):1375-8, 2010
                                        12. Stang A et al: Differentiation of benign from malignant focal splenic lesions using sulfur hexafluoride-filled microbubble contrast-enhanced pulse-inversion sonography. AJR Am J Roentgenol. 193(3):709-21, 2009
                                        13. von Herbay A et al: Contrast-enhanced ultrasonography with SonoVue: differentiation between benign and malignant lesions of the spleen. J Ultrasound Med. 28(4):421-34, 2009
                                        14. Görg C: The forgotten organ: contrast enhanced sonography of the spleen. Eur J Radiol. 64(2):189-201, 2007
                                        15. Pérez-Grueso MJ et al: Splenic focal lesions as manifestation of sarcoidosis: Characterization with contrast-enhanced sonography. J Clin Ultrasound. 35(7):405-8, 2007
                                        16. Abbott RM et al: primary vascular neoplasms of the spleen: Radiologic-pathologic correlation. AFIP Archives. 24(4):1137-63, 2004
                                        17. Ota T et al: Intrapancreatic accessory spleen: diagnosis using contrast enhanced ultrasound. Br J Radiol. 77(914):148-9, 2004
                                        18. Peddu P et al: Splenic abnormalities: a comparative review of ultrasound, microbubble-enhanced ultrasound and computed tomography. Clin Radiol. 59(9):777-92, 2004
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • CEUS TECHNIQUE

                                          • IMAGING

                                            CLINICAL IMPLICATIONS

                                            • Splenic Cysts

                                              • Splenic Abscess

                                                • Sarcoidosis

                                                  • Splenic Infarction

                                                    • Splenic Hemangioma

                                                      • Splenic Hamartoma

                                                        • Splenic Lymphangioma

                                                          • Accessory Spleens and Postsplenectomy Splenosis (Splenunculi)

                                                            CEUS TECHNIQUE

                                                            • CEUS Protocol Advice

                                                              Imaging

                                                              • Splenic Hamartoma

                                                                • Splenic Infarction

                                                                  • Splenic Cyst

                                                                    • Splenic Abscess

                                                                      • Sarcoidosis

                                                                        • Splenic Hemangioma

                                                                          • Splenic Lymphangioma

                                                                            • Accessory Spleens and Postsplenectomy Splenosis (Splenunculi)

                                                                              Selected References

                                                                              1. Sidhu PS et al: The EFSUMB Guidelines and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound (CEUS) in Non-Hepatic Applications: Update 2017 (Short Version). Ultraschall Med. 39(2):154-180, 2018
                                                                              2. Zavariz JD et al: Common and uncommon features of focal splenic lesions on contrast-enhanced ultrasound: a pictorial review. Radiol Bras. 50(6):395-404, 2017
                                                                              3. Knieling F et al: Spectrum, applicability and diagnostic capacity of contrast-enhanced ultrasound in pediatric patients and young adults after intravenous application - a retrospective trial. Ultraschall Med. 37(6):619-626, 2016
                                                                              4. Omar A et al: Contrast-enhanced ultrasound of the spleen. Ultrasound. 24(1):41-9, 2016
                                                                              5. Roman A et al: Splenic cystic lymphangioma with atypical ultrasound findings. J Med Ultrason (2001). 43(1):99-105, 2016
                                                                              6. Tana C et al: Hepatosplenic sarcoidosis: contrast-enhanced ultrasound findings and implications for clinical practice. Biomed Res Int. 2014:926203, 2014
                                                                              7. Caremani M et al: Focal splenic lesions: US findings. J Ultrasound. 16(2):65-74, 2013
                                                                              8. Grzelak P et al: Diagnostic potential of contrast-enhanced ultrasound (CEUS) in the assessment of spleen and liver granulomas in the course of sarcoidosis. Pneumonol Alergol Pol. 81(5):424-8, 2013
                                                                              9. Grzelak P et al: Use of contrast-enhanced ultrasonography in hepatosplenic sarcoidosis: Report of 2 cases. Pol J Radiol. 77(3):60-3, 2012
                                                                              10. Yu X et al: Real-time contrast-enhanced ultrasound in diagnosing of focal spleen lesions. Eur J Radiol. 81(3):430-6, 2012
                                                                              11. Wells IT et al: Differentiating a benign splenic lesion from an isolated metastasis with contrast-enhanced sonography. J Ultrasound Med. 29(9):1375-8, 2010
                                                                              12. Stang A et al: Differentiation of benign from malignant focal splenic lesions using sulfur hexafluoride-filled microbubble contrast-enhanced pulse-inversion sonography. AJR Am J Roentgenol. 193(3):709-21, 2009
                                                                              13. von Herbay A et al: Contrast-enhanced ultrasonography with SonoVue: differentiation between benign and malignant lesions of the spleen. J Ultrasound Med. 28(4):421-34, 2009
                                                                              14. Görg C: The forgotten organ: contrast enhanced sonography of the spleen. Eur J Radiol. 64(2):189-201, 2007
                                                                              15. Pérez-Grueso MJ et al: Splenic focal lesions as manifestation of sarcoidosis: Characterization with contrast-enhanced sonography. J Clin Ultrasound. 35(7):405-8, 2007
                                                                              16. Abbott RM et al: primary vascular neoplasms of the spleen: Radiologic-pathologic correlation. AFIP Archives. 24(4):1137-63, 2004
                                                                              17. Ota T et al: Intrapancreatic accessory spleen: diagnosis using contrast enhanced ultrasound. Br J Radiol. 77(914):148-9, 2004
                                                                              18. Peddu P et al: Splenic abnormalities: a comparative review of ultrasound, microbubble-enhanced ultrasound and computed tomography. Clin Radiol. 59(9):777-92, 2004