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Ultrasound
Diagnosis
Spleen
CEUS Spleen: Diffuse Disease
CEUS Spleen: Diffuse Disease
Julia Zavariz, MD; Annamaria Deganello, MD; Paul S. Sidhu, BSc, MBBS, MRCP, FRCR, DTM&H
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KEY FACTS

  • General Discussion

    • Imaging

      CEUS TECHNIQUE

      • CEUS Protocol Advice

        IMAGING

        • Homogeneous Splenomegaly

          • Small-Sized Spleen

            • Heterogeneous Spleen

              Selected References

              1. Sidhu PS et al: The EFSUMB guidelines and recommendations for the clinical practice of contrast-enhanced ultrasound (CEUS) in non-hepatic applications: update 2017 (long version). Ultraschall Med. 39(2):e2-e44, 2018
              2. Zavariz JD et al: Common and uncommon features of focal splenic lesions on contrast-enhanced ultrasound: a pictorial review. Radiol Bras. 50(6):395-404, 2017
              3. Knieling F et al: Spectrum, applicability and diagnostic capacity of contrast-enhanced ultrasound in pediatric patients and young adults after intravenous application - A retrospective trial. Ultraschall Med. 37(6):619-626, 2016
              4. Tana C et al: Hepatosplenic sarcoidosis: contrast-enhanced ultrasound findings and implications for clinical practice. Biomed Res Int. 2014:926203, 2014
              5. Grzelak P et al: Use of contrast-enhanced ultrasonography in hepatosplenic sarcoidosis: Report of 2 cases. Pol J Radiol. 77(3):60-3, 2012
              6. Görg C et al: Contrast enhanced ultrasound of splenic lymphoma involvement. Eur J Radiol. 80(2):169-74, 2011
              7. Benedetti E et al: Contrast-enhanced ultrasonography in nodular splenomegaly associated with type B Niemann-Pick disease: an atypical hemangioma enhancement pattern. J Ultrasound. 12(3):85-92, 2009
              8. Görg C: The forgotten organ: contrast enhanced sonography of the spleen. Eur J Radiol. 64(2):189-201, 2007
              9. Görg C et al: Contrast-enhanced sonography for differential diagnosis of an inhomogeneous spleen of unknown cause in patients with pain in the left upper quadrant. J Ultrasound Med. 25(6):729-34, 2006
              10. Tafuto S et al: Real-time contrast-enhanced specific ultrasound in staging and follow-up of splenic lymphomas. Front Biosci. 11:2224-9, 2006
              11. Lim AK et al: Evidence for spleen-specific uptake of a microbubble contrast agent: a quantitative study in healthy volunteers. Radiology. 231(3):785-8, 2004
              12. Peddu P et al: Splenic abnormalities: a comparative review of ultrasound, microbubble-enhanced ultrasound and computed tomography. Clin Radiol. 59(9):777-92, 2004
              Related Anatomy
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              Related Differential Diagnoses
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              References
              Tables

              Tables

              KEY FACTS

              • General Discussion

                • Imaging

                  CEUS TECHNIQUE

                  • CEUS Protocol Advice

                    IMAGING

                    • Homogeneous Splenomegaly

                      • Small-Sized Spleen

                        • Heterogeneous Spleen

                          Selected References

                          1. Sidhu PS et al: The EFSUMB guidelines and recommendations for the clinical practice of contrast-enhanced ultrasound (CEUS) in non-hepatic applications: update 2017 (long version). Ultraschall Med. 39(2):e2-e44, 2018
                          2. Zavariz JD et al: Common and uncommon features of focal splenic lesions on contrast-enhanced ultrasound: a pictorial review. Radiol Bras. 50(6):395-404, 2017
                          3. Knieling F et al: Spectrum, applicability and diagnostic capacity of contrast-enhanced ultrasound in pediatric patients and young adults after intravenous application - A retrospective trial. Ultraschall Med. 37(6):619-626, 2016
                          4. Tana C et al: Hepatosplenic sarcoidosis: contrast-enhanced ultrasound findings and implications for clinical practice. Biomed Res Int. 2014:926203, 2014
                          5. Grzelak P et al: Use of contrast-enhanced ultrasonography in hepatosplenic sarcoidosis: Report of 2 cases. Pol J Radiol. 77(3):60-3, 2012
                          6. Görg C et al: Contrast enhanced ultrasound of splenic lymphoma involvement. Eur J Radiol. 80(2):169-74, 2011
                          7. Benedetti E et al: Contrast-enhanced ultrasonography in nodular splenomegaly associated with type B Niemann-Pick disease: an atypical hemangioma enhancement pattern. J Ultrasound. 12(3):85-92, 2009
                          8. Görg C: The forgotten organ: contrast enhanced sonography of the spleen. Eur J Radiol. 64(2):189-201, 2007
                          9. Görg C et al: Contrast-enhanced sonography for differential diagnosis of an inhomogeneous spleen of unknown cause in patients with pain in the left upper quadrant. J Ultrasound Med. 25(6):729-34, 2006
                          10. Tafuto S et al: Real-time contrast-enhanced specific ultrasound in staging and follow-up of splenic lymphomas. Front Biosci. 11:2224-9, 2006
                          11. Lim AK et al: Evidence for spleen-specific uptake of a microbubble contrast agent: a quantitative study in healthy volunteers. Radiology. 231(3):785-8, 2004
                          12. Peddu P et al: Splenic abnormalities: a comparative review of ultrasound, microbubble-enhanced ultrasound and computed tomography. Clin Radiol. 59(9):777-92, 2004