Bookmarks
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
- Familial multilocular cystic disease of jaw
- Familial fibrosis of jaws
- Familial benign giant-cell tumor of jaw
Definitions
- Familial, bilateral, and symmetric fibroosseous jaw lesions
- Genetically distinct from fibrous dysplasia (FD)
- Round face and lower eyelid retraction → eyes raised to heaven or cherub-like appearance
- Familial, bilateral, and symmetric fibroosseous jaw lesions
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Papadaki ME et al: Cherubism: best clinical practice. Orphanet J Rare Dis. 7 Suppl 1:S6, 2012
- Orhan E et al: Idiopathic bilateral central giant cell reparative granuloma of jaws: a case report and literature review. Int J Pediatr Otorhinolaryngol. 74(5):547-52, 2010
- Mortellaro C et al: Diagnosis and treatment of familial cherubism characterized by early onset and rapid development. J Craniofac Surg. 20(1):116-20, 2009
- Roginsky VV et al: Familial cherubism: the experience of the Moscow Central Institute for Stomatology and Maxillo-Facial Surgery. Int J Oral Maxillofac Surg. 38(3):218-23, 2009
- Pontes FS et al: Aggressive case of cherubism: 17-year follow-up. Int J Pediatr Otorhinolaryngol. 71(5):831-5, 2007
- Jain V et al: Radiographic, CT and MRI features of cherubism. Pediatr Radiol. 36(10):1099-104, 2006
- Wolvius EB et al: Noonan-like/multiple giant cell lesion syndrome: report of a case and review of the literature. J Oral Maxillofac Surg. 64(8):1289-92, 2006
- Lee JS et al: Phenotypic and genotypic characterisation of Noonan-like/multiple giant cell lesion syndrome. J Med Genet. 42(2):e11, 2005
- Beaman FD et al: Imaging characteristics of cherubism. AJR Am J Roentgenol. 182(4):1051-4, 2004
- Ozkan Y et al: Clinical and radiological evaluation of cherubism: a sporadic case report and review of the literature. Int J Pediatr Otorhinolaryngol. 67(9):1005-12, 2003
- Lupescu I et al: [Helical CT and diagnostic evaluation of cranio-facial fibrous dysplasia.] J Radiol. 82(2):145-9, 2001
- Yamaguchi T et al: Cherubism: clinicopathologic features. Skeletal Radiol. 28(6):350-3, 1999
- Addante RR et al: Cherubism in a patient with Noonan's syndrome. J Oral Maxillofac Surg. 54(2):210-3, 1996
- Chomette G et al: Cherubism. Histo-enzymological and ultrastructural study. Int J Oral Maxillofac Surg. 17(4):219-23, 1988
Related Anatomy
Loading...
Related Differential Diagnoses
Loading...
References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
- Familial multilocular cystic disease of jaw
- Familial fibrosis of jaws
- Familial benign giant-cell tumor of jaw
Definitions
- Familial, bilateral, and symmetric fibroosseous jaw lesions
- Genetically distinct from fibrous dysplasia (FD)
- Round face and lower eyelid retraction → eyes raised to heaven or cherub-like appearance
- Familial, bilateral, and symmetric fibroosseous jaw lesions
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Papadaki ME et al: Cherubism: best clinical practice. Orphanet J Rare Dis. 7 Suppl 1:S6, 2012
- Orhan E et al: Idiopathic bilateral central giant cell reparative granuloma of jaws: a case report and literature review. Int J Pediatr Otorhinolaryngol. 74(5):547-52, 2010
- Mortellaro C et al: Diagnosis and treatment of familial cherubism characterized by early onset and rapid development. J Craniofac Surg. 20(1):116-20, 2009
- Roginsky VV et al: Familial cherubism: the experience of the Moscow Central Institute for Stomatology and Maxillo-Facial Surgery. Int J Oral Maxillofac Surg. 38(3):218-23, 2009
- Pontes FS et al: Aggressive case of cherubism: 17-year follow-up. Int J Pediatr Otorhinolaryngol. 71(5):831-5, 2007
- Jain V et al: Radiographic, CT and MRI features of cherubism. Pediatr Radiol. 36(10):1099-104, 2006
- Wolvius EB et al: Noonan-like/multiple giant cell lesion syndrome: report of a case and review of the literature. J Oral Maxillofac Surg. 64(8):1289-92, 2006
- Lee JS et al: Phenotypic and genotypic characterisation of Noonan-like/multiple giant cell lesion syndrome. J Med Genet. 42(2):e11, 2005
- Beaman FD et al: Imaging characteristics of cherubism. AJR Am J Roentgenol. 182(4):1051-4, 2004
- Ozkan Y et al: Clinical and radiological evaluation of cherubism: a sporadic case report and review of the literature. Int J Pediatr Otorhinolaryngol. 67(9):1005-12, 2003
- Lupescu I et al: [Helical CT and diagnostic evaluation of cranio-facial fibrous dysplasia.] J Radiol. 82(2):145-9, 2001
- Yamaguchi T et al: Cherubism: clinicopathologic features. Skeletal Radiol. 28(6):350-3, 1999
- Addante RR et al: Cherubism in a patient with Noonan's syndrome. J Oral Maxillofac Surg. 54(2):210-3, 1996
- Chomette G et al: Cherubism. Histo-enzymological and ultrastructural study. Int J Oral Maxillofac Surg. 17(4):219-23, 1988
