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Chondroblastoma
A. Carlson Merrow, Jr., MD, FAAP
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Epiphyseal chondromatous giant cell tumor, Codman tumor
          • Definitions

            • Benign to intermediate-grade bone tumor with immature cartilage cells (chondroblasts) in heterogeneous matrix

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Natural History & Prognosis

                              • Treatment

                                Selected References

                                1. Arkader A et al: Pediatric chondroblastoma and the need for lung staging at presentation. J Pediatr Orthop. 40(9):e894-7, 2020
                                2. John I et al: Chondroblastomas presenting in adulthood: a study of 39 patients with emphasis on histologic features and skeletal distribution. Histopathology. ePub, 2019
                                3. Laitinen MK et al: Chondroblastoma in pelvis and extremities- a single centre study of 177 cases. J Bone Oncol. 17:100248, 2019
                                4. Angelini A et al: Chondroblastoma of the foot: 40 cases from a single institution. J Foot Ankle Surg. 57(6):1105-9, 2018
                                5. Özer D et al: Chondroblastoma: an evaluation of the recurrences and functional outcomes following treatment. Acta Orthop Traumatol Turc. 52(6):415-8, 2018
                                6. Xiong Y et al: The effects of surgical treatment with chondroblastoma in children and adolescents in open epiphyseal plate of long bones. World J Surg Oncol. 16(1):14, 2018
                                7. Xie C et al: Radiofrequency ablation of chondroblastoma: long-term clinical and imaging outcomes. Eur Radiol. 25(4):1127-34, 2015
                                8. Xu H et al: Chondroblastoma of bone in the extremities: a multicenter retrospective study. J Bone Joint Surg Am. 97(11):925-31, 2015
                                9. Qasem SA et al: Cartilage-forming tumors. Semin Diagn Pathol. 31(1):10-20, 2014
                                10. Casadei R et al: Imaging tumors of the patella. Eur J Radiol. 82(12):2140-8, 2013
                                11. Douis H et al: The imaging of cartilaginous bone tumours. I. Benign lesions. Skeletal Radiol. 41(10):1195-212, 2012
                                12. Maheshwari AV et al: Metaphyseal and diaphyseal chondroblastomas. Skeletal Radiol. 40(12):1563-73, 2011
                                13. Reid LB et al: Chondroblastoma of the temporal bone: a case series, review, and suggested management strategy. Skull Base Rep. 1(2):71-82, 2011
                                14. Brien EW et al: Benign and malignant cartilage tumors of bone and joint: their anatomic and theoretical basis with an emphasis on radiology, pathology and clinical biology. II. Juxtacortical cartilage tumors. Skeletal Radiol. 28(1):1-20, 1999
                                15. Weatherall PT et al: Chondroblastoma: classic and confusing appearance at MR imaging. Radiology. 190(2):467-74, 1994
                                Related Anatomy
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                                Related Differential Diagnoses
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                                References
                                Tables

                                Tables

                                KEY FACTS

                                • Terminology

                                  • Imaging

                                    • Top Differential Diagnoses

                                      • Clinical Issues

                                        TERMINOLOGY

                                        • Synonyms

                                          • Epiphyseal chondromatous giant cell tumor, Codman tumor
                                        • Definitions

                                          • Benign to intermediate-grade bone tumor with immature cartilage cells (chondroblasts) in heterogeneous matrix

                                        IMAGING

                                        • General Features

                                          • Radiographic Findings

                                            • CT Findings

                                              • MR Findings

                                                • Imaging Recommendations

                                                  DIFFERENTIAL DIAGNOSIS

                                                    PATHOLOGY

                                                    • General Features

                                                      CLINICAL ISSUES

                                                      • Presentation

                                                        • Demographics

                                                          • Natural History & Prognosis

                                                            • Treatment

                                                              Selected References

                                                              1. Arkader A et al: Pediatric chondroblastoma and the need for lung staging at presentation. J Pediatr Orthop. 40(9):e894-7, 2020
                                                              2. John I et al: Chondroblastomas presenting in adulthood: a study of 39 patients with emphasis on histologic features and skeletal distribution. Histopathology. ePub, 2019
                                                              3. Laitinen MK et al: Chondroblastoma in pelvis and extremities- a single centre study of 177 cases. J Bone Oncol. 17:100248, 2019
                                                              4. Angelini A et al: Chondroblastoma of the foot: 40 cases from a single institution. J Foot Ankle Surg. 57(6):1105-9, 2018
                                                              5. Özer D et al: Chondroblastoma: an evaluation of the recurrences and functional outcomes following treatment. Acta Orthop Traumatol Turc. 52(6):415-8, 2018
                                                              6. Xiong Y et al: The effects of surgical treatment with chondroblastoma in children and adolescents in open epiphyseal plate of long bones. World J Surg Oncol. 16(1):14, 2018
                                                              7. Xie C et al: Radiofrequency ablation of chondroblastoma: long-term clinical and imaging outcomes. Eur Radiol. 25(4):1127-34, 2015
                                                              8. Xu H et al: Chondroblastoma of bone in the extremities: a multicenter retrospective study. J Bone Joint Surg Am. 97(11):925-31, 2015
                                                              9. Qasem SA et al: Cartilage-forming tumors. Semin Diagn Pathol. 31(1):10-20, 2014
                                                              10. Casadei R et al: Imaging tumors of the patella. Eur J Radiol. 82(12):2140-8, 2013
                                                              11. Douis H et al: The imaging of cartilaginous bone tumours. I. Benign lesions. Skeletal Radiol. 41(10):1195-212, 2012
                                                              12. Maheshwari AV et al: Metaphyseal and diaphyseal chondroblastomas. Skeletal Radiol. 40(12):1563-73, 2011
                                                              13. Reid LB et al: Chondroblastoma of the temporal bone: a case series, review, and suggested management strategy. Skull Base Rep. 1(2):71-82, 2011
                                                              14. Brien EW et al: Benign and malignant cartilage tumors of bone and joint: their anatomic and theoretical basis with an emphasis on radiology, pathology and clinical biology. II. Juxtacortical cartilage tumors. Skeletal Radiol. 28(1):1-20, 1999
                                                              15. Weatherall PT et al: Chondroblastoma: classic and confusing appearance at MR imaging. Radiology. 190(2):467-74, 1994