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Chondroma of Soft Tissue
Eric Walker, MD, MHA, FACR, FACHE; Catherine C. Roberts, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Extraskeletal chondroma, chondroma of soft parts
          • Definitions

            • Benign soft tissue lesion composed of chondrocytes that produce hyaline or myxoid cartilage arising in extraosseous and extrasynovial locations

          IMAGING

          • General Features

            • Ultrasonographic Findings

              • Imaging Recommendations

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      Selected References

                                      1. Kao YC et al: What is new about the molecular genetics in matrix-producing soft tissue tumors? The contributions to pathogenetic understanding and diagnostic classification. Virchows Arch. 476(1):121-34, 2020
                                      2. Rosenberg AE: Soft tissue chondroma. In Fletcher CDM et al: World Health Organization Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 222-3, 2020
                                      3. Amary F et al: Synovial chondromatosis and soft tissue chondroma: extraosseous cartilaginous tumor defined by FN1 gene rearrangement. Mod Pathol. 32(12):1762-71, 2019
                                      4. Kransdorf MJ et al: Extraskeletal osseous and cartilaginous lesions. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 565-7, 2014
                                      5. Walker EA et al: Imaging characteristics of tenosynovial and bursal chondromatosis. Skeletal Radiol. 40(3):317-25, 2011
                                      6. Baek HJ et al: Subungual tumors: clinicopathologic correlation with US and MR imaging findings. Radiographics. 30(6):1621-36, 2010
                                      7. Le Corroller T et al: Diffuse mineralization of forearm extraskeletal chondroma. Joint Bone Spine. 75(4):479-81, 2008
                                      8. Weiss SW et al: Cartilaginous soft tissue tumors. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 1017-23, 2008
                                      9. Hondar Wu HT et al: Imaging and pathological correlation of soft-tissue chondroma: a serial five-case study and literature review. Clin Imaging. 30(1):32-6, 2006
                                      10. Fetsch JF et al: Tenosynovial (extraarticular) chondromatosis: an analysis of 37 cases of an underrecognized clinicopathologic entity with a strong predilection for the hands and feet and a high local recurrence rate. Am J Surg Pathol. 27(9):1260-8, 2003
                                      11. Nayler S et al: Soft tissue chondroma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 180-1, 2002
                                      12. Bansal M et al: Soft tissue chondromas: diagnosis and differential diagnosis. Skeletal Radiol. 22(5):309-15, 1993
                                      13. Kransdorf MJ et al: From the archives of the AFIP. Extraskeletal osseous and cartilaginous tumors of the extremities. Radiographics. 13(4):853-84, 1993
                                      Related Anatomy
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Pathology

                                            • Clinical Issues

                                              TERMINOLOGY

                                              • Synonyms

                                                • Extraskeletal chondroma, chondroma of soft parts
                                              • Definitions

                                                • Benign soft tissue lesion composed of chondrocytes that produce hyaline or myxoid cartilage arising in extraosseous and extrasynovial locations

                                              IMAGING

                                              • General Features

                                                • Ultrasonographic Findings

                                                  • Imaging Recommendations

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          Selected References

                                                                          1. Kao YC et al: What is new about the molecular genetics in matrix-producing soft tissue tumors? The contributions to pathogenetic understanding and diagnostic classification. Virchows Arch. 476(1):121-34, 2020
                                                                          2. Rosenberg AE: Soft tissue chondroma. In Fletcher CDM et al: World Health Organization Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 222-3, 2020
                                                                          3. Amary F et al: Synovial chondromatosis and soft tissue chondroma: extraosseous cartilaginous tumor defined by FN1 gene rearrangement. Mod Pathol. 32(12):1762-71, 2019
                                                                          4. Kransdorf MJ et al: Extraskeletal osseous and cartilaginous lesions. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 565-7, 2014
                                                                          5. Walker EA et al: Imaging characteristics of tenosynovial and bursal chondromatosis. Skeletal Radiol. 40(3):317-25, 2011
                                                                          6. Baek HJ et al: Subungual tumors: clinicopathologic correlation with US and MR imaging findings. Radiographics. 30(6):1621-36, 2010
                                                                          7. Le Corroller T et al: Diffuse mineralization of forearm extraskeletal chondroma. Joint Bone Spine. 75(4):479-81, 2008
                                                                          8. Weiss SW et al: Cartilaginous soft tissue tumors. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 1017-23, 2008
                                                                          9. Hondar Wu HT et al: Imaging and pathological correlation of soft-tissue chondroma: a serial five-case study and literature review. Clin Imaging. 30(1):32-6, 2006
                                                                          10. Fetsch JF et al: Tenosynovial (extraarticular) chondromatosis: an analysis of 37 cases of an underrecognized clinicopathologic entity with a strong predilection for the hands and feet and a high local recurrence rate. Am J Surg Pathol. 27(9):1260-8, 2003
                                                                          11. Nayler S et al: Soft tissue chondroma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 180-1, 2002
                                                                          12. Bansal M et al: Soft tissue chondromas: diagnosis and differential diagnosis. Skeletal Radiol. 22(5):309-15, 1993
                                                                          13. Kransdorf MJ et al: From the archives of the AFIP. Extraskeletal osseous and cartilaginous tumors of the extremities. Radiographics. 13(4):853-84, 1993