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Chondrosarcoma of Head and Neck
H. Ric Harnsberger, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Chondrosarcoma of head & neck (CSa H&N)
              • Definitions

                • Malignant tumor arising from H&N cartilage or bone characterized by formation of cartilaginous matrix by neoplastic cells

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Angiographic Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            Selected References

                                            1. González-Pérez LM et al: Temporomandibular joint chondrosarcoma: Case report. J Craniomaxillofac Surg. 39(1):79-83, 2011
                                            2. Amichetti M et al: A systematic review of proton therapy in the treatment of chondrosarcoma of the skull base. Neurosurg Rev. 33(2):155-65, 2010
                                            3. Hong P et al: Chondrosarcoma of the head and neck: report of 11 cases and literature review. J Otolaryngol Head Neck Surg. 38(2):279-85, 2009
                                            4. Bathala S et al: Chondrosarcoma of larynx: review of literature and clinical experience. J Laryngol Otol. 122(10):1127-9, 2008
                                            5. Cho YH et al: Chordomas and chondrosarcomas of the skull base: comparative analysis of clinical results in 30 patients. Neurosurg Rev. 31(1):35-43; discussion 43, 2008
                                            6. Sanna M et al: Chondrosarcomas of the jugular foramen. Laryngoscope. 118(10):1719-28, 2008
                                            7. Inwards CY: Update on cartilage forming tumors of the head and neck. Head Neck Pathol. 1(1):67-74, 2007
                                            8. Lustig LR et al: Chondrosarcomas of the skull base and temporal bone. J Laryngol Otol. 121(8):725-35, 2007
                                            9. Sauter A et al: Chondrosarcoma of the larynx and review of the literature. Anticancer Res. 27(4C):2925-9, 2007
                                            10. Noël G et al: Chondrosarcomas of the base of the skull in Ollier's disease or Maffucci's syndrome--three case reports and review of the literature. Acta Oncol. 43(8):705-10, 2004
                                            11. Murphey MD et al: From the archives of the AFIP: imaging of primary chondrosarcoma: radiologic-pathologic correlation. Radiographics. 23(5):1245-78, 2003
                                            12. Neff B et al: Chondrosarcoma of the skull base. Laryngoscope. 112(1):134-9, 2002
                                            13. Schmidinger A et al: Natural history of chondroid skull base lesions--case report and review. Neuroradiology. 44(3):268-71, 2002
                                            14. Thompson LD et al: Chondrosarcoma of the larynx: a clinicopathologic study of 111 cases with a review of the literature. Am J Surg Pathol. 26(7):836-51, 2002
                                            15. Yamamoto S et al: Chondrosarcoma of the nasal septum. Skeletal Radiol. 31(9):543-6, 2002
                                            16. Rosenberg AE et al: Chondrosarcoma of the base of the skull: a clinicopathologic study of 200 cases with emphasis on its distinction from chordoma. Am J Surg Pathol. 23(11):1370-8, 1999
                                            17. Lewis JE et al: Cartilaginous tumors of the larynx: clinicopathologic review of 47 cases. Ann Otol Rhinol Laryngol. 106(2):94-100, 1997
                                            18. Meyers SP et al: Chondrosarcomas of the skull base: MR imaging features. Radiology. 184(1):103-8, 1992
                                            19. Mishell JH et al: Chondrosarcoma of the larynx. Diagnosis with magnetic resonance imaging and computed tomography. Arch Otolaryngol Head Neck Surg. 116(11):1338-41, 1990
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Abbreviations

                                                          • Chondrosarcoma of head & neck (CSa H&N)
                                                        • Definitions

                                                          • Malignant tumor arising from H&N cartilage or bone characterized by formation of cartilaginous matrix by neoplastic cells

                                                        IMAGING

                                                        • General Features

                                                          • CT Findings

                                                            • MR Findings

                                                              • Angiographic Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Staging, Grading, & Classification

                                                                        • Gross Pathologic & Surgical Features

                                                                          • Microscopic Features

                                                                            CLINICAL ISSUES

                                                                            • Presentation

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Consider

                                                                                      Selected References

                                                                                      1. González-Pérez LM et al: Temporomandibular joint chondrosarcoma: Case report. J Craniomaxillofac Surg. 39(1):79-83, 2011
                                                                                      2. Amichetti M et al: A systematic review of proton therapy in the treatment of chondrosarcoma of the skull base. Neurosurg Rev. 33(2):155-65, 2010
                                                                                      3. Hong P et al: Chondrosarcoma of the head and neck: report of 11 cases and literature review. J Otolaryngol Head Neck Surg. 38(2):279-85, 2009
                                                                                      4. Bathala S et al: Chondrosarcoma of larynx: review of literature and clinical experience. J Laryngol Otol. 122(10):1127-9, 2008
                                                                                      5. Cho YH et al: Chordomas and chondrosarcomas of the skull base: comparative analysis of clinical results in 30 patients. Neurosurg Rev. 31(1):35-43; discussion 43, 2008
                                                                                      6. Sanna M et al: Chondrosarcomas of the jugular foramen. Laryngoscope. 118(10):1719-28, 2008
                                                                                      7. Inwards CY: Update on cartilage forming tumors of the head and neck. Head Neck Pathol. 1(1):67-74, 2007
                                                                                      8. Lustig LR et al: Chondrosarcomas of the skull base and temporal bone. J Laryngol Otol. 121(8):725-35, 2007
                                                                                      9. Sauter A et al: Chondrosarcoma of the larynx and review of the literature. Anticancer Res. 27(4C):2925-9, 2007
                                                                                      10. Noël G et al: Chondrosarcomas of the base of the skull in Ollier's disease or Maffucci's syndrome--three case reports and review of the literature. Acta Oncol. 43(8):705-10, 2004
                                                                                      11. Murphey MD et al: From the archives of the AFIP: imaging of primary chondrosarcoma: radiologic-pathologic correlation. Radiographics. 23(5):1245-78, 2003
                                                                                      12. Neff B et al: Chondrosarcoma of the skull base. Laryngoscope. 112(1):134-9, 2002
                                                                                      13. Schmidinger A et al: Natural history of chondroid skull base lesions--case report and review. Neuroradiology. 44(3):268-71, 2002
                                                                                      14. Thompson LD et al: Chondrosarcoma of the larynx: a clinicopathologic study of 111 cases with a review of the literature. Am J Surg Pathol. 26(7):836-51, 2002
                                                                                      15. Yamamoto S et al: Chondrosarcoma of the nasal septum. Skeletal Radiol. 31(9):543-6, 2002
                                                                                      16. Rosenberg AE et al: Chondrosarcoma of the base of the skull: a clinicopathologic study of 200 cases with emphasis on its distinction from chordoma. Am J Surg Pathol. 23(11):1370-8, 1999
                                                                                      17. Lewis JE et al: Cartilaginous tumors of the larynx: clinicopathologic review of 47 cases. Ann Otol Rhinol Laryngol. 106(2):94-100, 1997
                                                                                      18. Meyers SP et al: Chondrosarcomas of the skull base: MR imaging features. Radiology. 184(1):103-8, 1992
                                                                                      19. Mishell JH et al: Chondrosarcoma of the larynx. Diagnosis with magnetic resonance imaging and computed tomography. Arch Otolaryngol Head Neck Surg. 116(11):1338-41, 1990