Malignant tumor of connective tissue, characterized by formation of cartilage matrix by tumor cells
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
Histologic Subtypes
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Littrell LA et al: Chondrosarcoma arising within synovial chondromatosis of the lumbar spine. Skeletal Radiol. 48(9):1443-9, 2019
Song K et al: Development and validation of nomograms predicting overall and cancer-specific survival of spinal chondrosarcoma patients. Spine (Phila Pa 1976). 43(21):E1281-9, 2018
Fisher CG et al: Surgical management of spinal chondrosarcomas. Spine (Phila Pa 1976). 41(8):678-85, 2016
Groves ML et al: Epidemiologic, functional, and oncologic outcome analysis of spinal sarcomas treated surgically at a single institution over 10 years. Spine J. 15(1):110-4, 2015
Ruivo C et al: Spinal chondrosarcoma arising from a solitary lumbar osteochondroma. JBR-BTR. 97(1):21-4, 2014
Yin H et al: Prognostic factors of patients with spinal chondrosarcoma: a retrospective analysis of 98 consecutive patients in a single center. Ann Surg Oncol. 21(11):3572-8, 2014
Boriani S et al: Challenges of local recurrence and cure in low grade malignant tumors of the spine. Spine (Phila Pa 1976). 34(22 Suppl):S48-57, 2009
McLoughlin GS et al: Chondroma/chondrosarcoma of the spine. Neurosurg Clin N Am. 19(1):57-63, 2008
Rao G et al: Surgical management of primary and metastatic sarcoma of the mobile spine. J Neurosurg Spine. 9(2):120-8, 2008
Lloret I et al: Primary spinal chondrosarcoma: radiologic findings with pathologic correlation. Acta Radiol. 47(1):77-84, 2006
Murphey MD et al: From the archives of the AFIP: imaging of primary chondrosarcoma: radiologic-pathologic correlation. Radiographics. 23(5):1245-78, 2003
Boriani S et al: Chondrosarcoma of the mobile spine: report on 22 cases. Spine (Phila Pa 1976). 25(7):804-12, 2000
Björnsson J et al: Primary chondrosarcoma of long bones and limb girdles. Cancer. 83(10):2105-19, 1998
Dorfman HD et al: Bone tumors. 1st ed. St. Louis: Mosby. 353-440, 1998
Greenspan A et al: Differential diagnosis of tumors and tumor-like lesions of bones and joints. 1st ed. Philadelphia: Lippincott-Raven. 169-98, 1998
Leis AA et al: Chondrosarcoma of the spine and thyroid carcinoma following radiation therapy for Hodgkin's lymphoma. Neurology. 48(6):1710-2, 1997
Swarts SJ et al: Chromosomal abnormalities in low grade chondrosarcoma and a review of the literature. Cancer Genet Cytogenet. 98(2):126-30, 1997
Mercuri M et al: Dedifferentiated chondrosarcoma. Skeletal Radiol. 24(6):409-16, 1995
Aoki J et al: MR of enchondroma and chondrosarcoma: rings and arcs of Gd-DTPA enhancement. J Comput Assist Tomogr. 15(6):1011-6, 1991
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Chondrosarcoma (CHS)
Definitions
Malignant tumor of connective tissue, characterized by formation of cartilage matrix by tumor cells
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
Histologic Subtypes
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Littrell LA et al: Chondrosarcoma arising within synovial chondromatosis of the lumbar spine. Skeletal Radiol. 48(9):1443-9, 2019
Song K et al: Development and validation of nomograms predicting overall and cancer-specific survival of spinal chondrosarcoma patients. Spine (Phila Pa 1976). 43(21):E1281-9, 2018
Fisher CG et al: Surgical management of spinal chondrosarcomas. Spine (Phila Pa 1976). 41(8):678-85, 2016
Groves ML et al: Epidemiologic, functional, and oncologic outcome analysis of spinal sarcomas treated surgically at a single institution over 10 years. Spine J. 15(1):110-4, 2015
Ruivo C et al: Spinal chondrosarcoma arising from a solitary lumbar osteochondroma. JBR-BTR. 97(1):21-4, 2014
Yin H et al: Prognostic factors of patients with spinal chondrosarcoma: a retrospective analysis of 98 consecutive patients in a single center. Ann Surg Oncol. 21(11):3572-8, 2014
Boriani S et al: Challenges of local recurrence and cure in low grade malignant tumors of the spine. Spine (Phila Pa 1976). 34(22 Suppl):S48-57, 2009
McLoughlin GS et al: Chondroma/chondrosarcoma of the spine. Neurosurg Clin N Am. 19(1):57-63, 2008
Rao G et al: Surgical management of primary and metastatic sarcoma of the mobile spine. J Neurosurg Spine. 9(2):120-8, 2008
Lloret I et al: Primary spinal chondrosarcoma: radiologic findings with pathologic correlation. Acta Radiol. 47(1):77-84, 2006
Murphey MD et al: From the archives of the AFIP: imaging of primary chondrosarcoma: radiologic-pathologic correlation. Radiographics. 23(5):1245-78, 2003
Boriani S et al: Chondrosarcoma of the mobile spine: report on 22 cases. Spine (Phila Pa 1976). 25(7):804-12, 2000
Björnsson J et al: Primary chondrosarcoma of long bones and limb girdles. Cancer. 83(10):2105-19, 1998
Dorfman HD et al: Bone tumors. 1st ed. St. Louis: Mosby. 353-440, 1998
Greenspan A et al: Differential diagnosis of tumors and tumor-like lesions of bones and joints. 1st ed. Philadelphia: Lippincott-Raven. 169-98, 1998
Leis AA et al: Chondrosarcoma of the spine and thyroid carcinoma following radiation therapy for Hodgkin's lymphoma. Neurology. 48(6):1710-2, 1997
Swarts SJ et al: Chromosomal abnormalities in low grade chondrosarcoma and a review of the literature. Cancer Genet Cytogenet. 98(2):126-30, 1997
Mercuri M et al: Dedifferentiated chondrosarcoma. Skeletal Radiol. 24(6):409-16, 1995
Aoki J et al: MR of enchondroma and chondrosarcoma: rings and arcs of Gd-DTPA enhancement. J Comput Assist Tomogr. 15(6):1011-6, 1991
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