Rare, low-grade primary malignant tumor of notochord origin
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Zweckberger K et al: Clivus chordomas: heterogeneous tumor extension requires adapted surgical approaches. Clin Neurol Neurosurg. 199:106305, 2020
Guan X et al: The preliminary results of proton and carbon ion therapy for chordoma and chondrosarcoma of the skull base and cervical spine. Radiat Oncol. 14(1):206, 2019
Lin E et al: Prognostic implications of gadolinium enhancement of skull base chordomas. AJNR Am J Neuroradiol. 39(8):1509-14, 2018
Tian K et al: MR Imaging grading system for skull base chordoma. AJNR Am J Neuroradiol. 38(6):1206-11, 2017
Lau CS et al: Pediatric chordomas: a population-based clinical outcome study involving 86 patients from the surveillance, epidemiology, and end result (SEER) Database (1973-2011). Pediatr Neurosurg. 51(3):127-36, 2016
Yasuda M et al: Chordomas of the skull base and cervical spine: clinical outcomes associated with a multimodal surgical resection combined with proton-beam radiation in 40 patients. Neurosurg Rev. 35(2):171-82; discussion 182-3, 2012
Brennan PM et al: Chordoma masquerading as a nerve root tumour -- a clinical lesson. Br J Radiol. 82(983):e231-4, 2009
Jiang L et al: Upper cervical spine chordoma of C2-C3. Eur Spine J. 18(3):293-298; discussion 298-300, 2009
Zhou H et al: Cervical chordoma in childhood without typical vertebral bony destruction: case report and review of the literature. Spine (Phila Pa 1976). 34(14):E493-7, 2009
Yamaguchi T et al: Distinguishing benign notochordal cell tumors from vertebral chordoma. Skeletal Radiol. 37(4):291-9, 2008
Singh N et al: Cervical chordoma presenting as retropharyngeal mass and dysphonia: Case report and literature review. Australas Radiol. 51 Suppl:B183-8, 2007
Lin CY et al: Chordoma detected on F-18 FDG PET. Clin Nucl Med. 31(8):506-7, 2006
Smolders D et al: Value of MRI in the diagnosis of non-clival, non-sacral chordoma. Skeletal Radiol. 32(6): 343-50, 2003
Wippold FJ 2nd et al: Clinical and imaging features of cervical chordoma. AJR Am J Roentgenol. 172(5): 1423-6, 1999
Murphey MD et al: From the archives of the AFIP. Primary tumors of the spine: radiologic pathologic correlation. Radiographics. 16(5): 1131-58, 1996
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Perivertebral space (PVS)
Definitions
Rare, low-grade primary malignant tumor of notochord origin
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Zweckberger K et al: Clivus chordomas: heterogeneous tumor extension requires adapted surgical approaches. Clin Neurol Neurosurg. 199:106305, 2020
Guan X et al: The preliminary results of proton and carbon ion therapy for chordoma and chondrosarcoma of the skull base and cervical spine. Radiat Oncol. 14(1):206, 2019
Lin E et al: Prognostic implications of gadolinium enhancement of skull base chordomas. AJNR Am J Neuroradiol. 39(8):1509-14, 2018
Tian K et al: MR Imaging grading system for skull base chordoma. AJNR Am J Neuroradiol. 38(6):1206-11, 2017
Lau CS et al: Pediatric chordomas: a population-based clinical outcome study involving 86 patients from the surveillance, epidemiology, and end result (SEER) Database (1973-2011). Pediatr Neurosurg. 51(3):127-36, 2016
Yasuda M et al: Chordomas of the skull base and cervical spine: clinical outcomes associated with a multimodal surgical resection combined with proton-beam radiation in 40 patients. Neurosurg Rev. 35(2):171-82; discussion 182-3, 2012
Brennan PM et al: Chordoma masquerading as a nerve root tumour -- a clinical lesson. Br J Radiol. 82(983):e231-4, 2009
Jiang L et al: Upper cervical spine chordoma of C2-C3. Eur Spine J. 18(3):293-298; discussion 298-300, 2009
Zhou H et al: Cervical chordoma in childhood without typical vertebral bony destruction: case report and review of the literature. Spine (Phila Pa 1976). 34(14):E493-7, 2009
Yamaguchi T et al: Distinguishing benign notochordal cell tumors from vertebral chordoma. Skeletal Radiol. 37(4):291-9, 2008
Singh N et al: Cervical chordoma presenting as retropharyngeal mass and dysphonia: Case report and literature review. Australas Radiol. 51 Suppl:B183-8, 2007
Lin CY et al: Chordoma detected on F-18 FDG PET. Clin Nucl Med. 31(8):506-7, 2006
Smolders D et al: Value of MRI in the diagnosis of non-clival, non-sacral chordoma. Skeletal Radiol. 32(6): 343-50, 2003
Wippold FJ 2nd et al: Clinical and imaging features of cervical chordoma. AJR Am J Roentgenol. 172(5): 1423-6, 1999
Murphey MD et al: From the archives of the AFIP. Primary tumors of the spine: radiologic pathologic correlation. Radiographics. 16(5): 1131-58, 1996
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