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Choroid Plexus Cyst
Roya Sohaey, MD
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Diagnostic Checklist

        TERMINOLOGY

        • Abbreviations

          • Choroid plexus cyst (CPC)
        • Definitions

          • Choroid plexus are organs in cerebral ventricular system that produce cerebrospinal fluid (CSF)
          • CPCs are entrapment of CSF in choroid plexus (CP)

        IMAGING

        • General Features

          • Ultrasonographic Findings

            • Imaging Recommendations

              DIFFERENTIAL DIAGNOSIS

                PATHOLOGY

                • General Features

                  CLINICAL ISSUES

                  • Presentation

                    • Demographics

                      • Natural History & Prognosis

                        • Treatment

                          DIAGNOSTIC CHECKLIST

                          • Consider

                            Selected References

                            1. Reddy UM et al: Fetal imaging: executive summary of a joint Eunice Kennedy Shriver National Institute of Child Health and Human Development, Society for Maternal-Fetal Medicine, American Institute of Ultrasound in Medicine, American College of Obstetricians and Gynecologists, American College of Radiology, Society for Pediatric Radiology, and Society of Radiologists in Ultrasound Fetal Imaging Workshop. J Ultrasound Med. 33(5):745-57, 2014
                            2. Sonek J et al: Second trimester ultrasound markers of fetal aneuploidy. Clin Obstet Gynecol. 57(1):159-81, 2014
                            3. DiPietro JA et al: Isolated prenatal choroid plexus cysts do not affect child development. Prenat Diagn. 31(8):745-9, 2011
                            4. Beke A et al: Risk of chromosome abnormalities in the presence of bilateral or unilateral choroid plexus cysts. Fetal Diagn Ther. 23(3):185-91, 2008
                            5. Dagklis T et al: Choroid plexus cyst, intracardiac echogenic focus, hyperechogenic bowel and hydronephrosis in screening for trisomy 21 at 11 + 0 to 13 + 6 weeks. Ultrasound Obstet Gynecol. 31(2):132-5, 2008
                            6. Watson WJ et al: Sonographic findings of trisomy 18 in the second trimester of pregnancy. J Ultrasound Med. 27(7):1033-8; quiz 1039-40, 2008
                            7. Ouzounian JG et al: Isolated choroid plexus cyst or echogenic cardiac focus on prenatal ultrasound: is genetic amniocentesis indicated? Am J Obstet Gynecol. 196(6):595, 2007
                            8. Bronsteen R et al: Second-trimester sonography and trisomy 18: the significance of isolated choroid plexus cysts after an examination that includes the fetal hands. J Ultrasound Med. 23(2):241-5, 2004
                            9. Doubilet PM et al: Choroid plexus cyst and echogenic intracardiac focus in women at low risk for chromosomal anomalies: the obligation to inform the mother. J Ultrasound Med. 23(7):883-5, 2004
                            10. Rochon M et al: Controversial ultrasound findings. Obstet Gynecol Clin North Am. 31(1):61-99, 2004
                            11. Sahinoglu Z et al: Second trimester choroid plexus cysts and trisomy 18. Int J Gynaecol Obstet. 85(1):24-9, 2004
                            12. Souter VL et al: Correlation of second-trimester sonography and biochemical markers. Obstet Gynecol Surv. 59(11):758-760, 2004
                            13. Turner SR et al: Sonography of fetal choroid plexus cysts: detection depends on cyst size and gestational age. J Ultrasound Med. 22(11):1219-27, 2003
                            14. Ghidini A et al: Isolated fetal choroid plexus cysts: role of ultrasonography in establishment of the risk of trisomy 18. Am J Obstet Gynecol. 182(4):972-7, 2000
                            15. Chitty LS et al: The significance of choroid plexus cysts in an unselected population: results of a multicenter study. Ultrasound Obstet Gynecol. 12(6):391-7, 1998
                            16. Gupta JK et al: Management of fetal choroid plexus cysts. Br J Obstet Gynaecol. 104(8):881-6, 1997
                            17. Gray DL et al: Is genetic amniocentesis warranted when isolated choroid plexus cysts are found? Prenat Diagn. 16(11):983-90, 1996
                            18. Gupta JK et al: Clinical significance of fetal choroid plexus cysts. Lancet. 346(8977):724-9, 1995
                            Related Anatomy
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                            Related Differential Diagnoses
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                            References
                            Tables

                            Tables

                            KEY FACTS

                            • Imaging

                              • Top Differential Diagnoses

                                • Diagnostic Checklist

                                  TERMINOLOGY

                                  • Abbreviations

                                    • Choroid plexus cyst (CPC)
                                  • Definitions

                                    • Choroid plexus are organs in cerebral ventricular system that produce cerebrospinal fluid (CSF)
                                    • CPCs are entrapment of CSF in choroid plexus (CP)

                                  IMAGING

                                  • General Features

                                    • Ultrasonographic Findings

                                      • Imaging Recommendations

                                        DIFFERENTIAL DIAGNOSIS

                                          PATHOLOGY

                                          • General Features

                                            CLINICAL ISSUES

                                            • Presentation

                                              • Demographics

                                                • Natural History & Prognosis

                                                  • Treatment

                                                    DIAGNOSTIC CHECKLIST

                                                    • Consider

                                                      Selected References

                                                      1. Reddy UM et al: Fetal imaging: executive summary of a joint Eunice Kennedy Shriver National Institute of Child Health and Human Development, Society for Maternal-Fetal Medicine, American Institute of Ultrasound in Medicine, American College of Obstetricians and Gynecologists, American College of Radiology, Society for Pediatric Radiology, and Society of Radiologists in Ultrasound Fetal Imaging Workshop. J Ultrasound Med. 33(5):745-57, 2014
                                                      2. Sonek J et al: Second trimester ultrasound markers of fetal aneuploidy. Clin Obstet Gynecol. 57(1):159-81, 2014
                                                      3. DiPietro JA et al: Isolated prenatal choroid plexus cysts do not affect child development. Prenat Diagn. 31(8):745-9, 2011
                                                      4. Beke A et al: Risk of chromosome abnormalities in the presence of bilateral or unilateral choroid plexus cysts. Fetal Diagn Ther. 23(3):185-91, 2008
                                                      5. Dagklis T et al: Choroid plexus cyst, intracardiac echogenic focus, hyperechogenic bowel and hydronephrosis in screening for trisomy 21 at 11 + 0 to 13 + 6 weeks. Ultrasound Obstet Gynecol. 31(2):132-5, 2008
                                                      6. Watson WJ et al: Sonographic findings of trisomy 18 in the second trimester of pregnancy. J Ultrasound Med. 27(7):1033-8; quiz 1039-40, 2008
                                                      7. Ouzounian JG et al: Isolated choroid plexus cyst or echogenic cardiac focus on prenatal ultrasound: is genetic amniocentesis indicated? Am J Obstet Gynecol. 196(6):595, 2007
                                                      8. Bronsteen R et al: Second-trimester sonography and trisomy 18: the significance of isolated choroid plexus cysts after an examination that includes the fetal hands. J Ultrasound Med. 23(2):241-5, 2004
                                                      9. Doubilet PM et al: Choroid plexus cyst and echogenic intracardiac focus in women at low risk for chromosomal anomalies: the obligation to inform the mother. J Ultrasound Med. 23(7):883-5, 2004
                                                      10. Rochon M et al: Controversial ultrasound findings. Obstet Gynecol Clin North Am. 31(1):61-99, 2004
                                                      11. Sahinoglu Z et al: Second trimester choroid plexus cysts and trisomy 18. Int J Gynaecol Obstet. 85(1):24-9, 2004
                                                      12. Souter VL et al: Correlation of second-trimester sonography and biochemical markers. Obstet Gynecol Surv. 59(11):758-760, 2004
                                                      13. Turner SR et al: Sonography of fetal choroid plexus cysts: detection depends on cyst size and gestational age. J Ultrasound Med. 22(11):1219-27, 2003
                                                      14. Ghidini A et al: Isolated fetal choroid plexus cysts: role of ultrasonography in establishment of the risk of trisomy 18. Am J Obstet Gynecol. 182(4):972-7, 2000
                                                      15. Chitty LS et al: The significance of choroid plexus cysts in an unselected population: results of a multicenter study. Ultrasound Obstet Gynecol. 12(6):391-7, 1998
                                                      16. Gupta JK et al: Management of fetal choroid plexus cysts. Br J Obstet Gynaecol. 104(8):881-6, 1997
                                                      17. Gray DL et al: Is genetic amniocentesis warranted when isolated choroid plexus cysts are found? Prenat Diagn. 16(11):983-90, 1996
                                                      18. Gupta JK et al: Clinical significance of fetal choroid plexus cysts. Lancet. 346(8977):724-9, 1995