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Choroid Plexus Cyst
Luke L. Linscott, MDAnne G. Osborn, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Choroid plexus cyst (CPC)
              • Choroid plexus xanthogranuloma (CPX)
            • Definitions

              • Nonneoplastic, noninflammatory cysts of choroid plexus
                • Lined by compressed connective tissue
                • Adult: CPC is common incidental finding on imaging studies in older patients (~ 40% prevalence)
                • Fetus: CPCs seen in 1-2% of 2nd-trimester pregnancies

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Maekawa T et al: Choroid plexus cysts analyzed using diffusion-weighted imaging with short diffusion-time. Magn Reson Imaging. 57:323-7, 2019
                                          2. Winter TC et al: How to integrate cell-free DNA screening with sonographic markers for aneuploidy: an update. AJR Am J Roentgenol. 210(4):906-12, 2018
                                          3. Zhang S et al: A retrospective study of cytogenetic results from amniotic fluid in 5328 fetuses with abnormal obstetric sonographic findings. J Ultrasound Med. 36(9):1809-17, 2017
                                          4. Spennato P et al: Acute triventricular hydrocephalus caused by choroid plexus cysts: a diagnostic and neurosurgical challenge. Neurosurg Focus. 41(5):E9, 2016
                                          5. de Lara D et al: Endoscopic treatment of a third ventricle choroid plexus cyst. Neurosurg Focus. 34(1 Suppl):Video 9, 2013
                                          6. Moreau E et al: Incidental bilateral xanthogranuloma of the lateral ventricles at autopsy--a case report. J Forensic Leg Med. 20(6):647-9, 2013
                                          7. Norton KI et al: Prevalence of choroid plexus cysts in term and near-term infants with congenital heart disease. AJR Am J Roentgenol. 196(3):W326-9, 2011
                                          8. Peltier J et al: [Rare tumors of the lateral ventricle. Review of the literature.] Neurochirurgie. 57(4-6):225-9, 2011
                                          9. Naeini RM et al: Spectrum of choroid plexus lesions in children. AJR Am J Roentgenol. 192(1):32-40, 2009
                                          10. Herman TE et al: Aicardi syndrome choroid plexus cysts. J Perinatol. 27(5):323-4, 2007
                                          11. Kinoshita T et al: Clinically silent choroid plexus cyst: evaluation by diffusion-weighted MRI. Neuroradiology. 47(4):251-5, 2005
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Choroid plexus cyst (CPC)
                                                      • Choroid plexus xanthogranuloma (CPX)
                                                    • Definitions

                                                      • Nonneoplastic, noninflammatory cysts of choroid plexus
                                                        • Lined by compressed connective tissue
                                                        • Adult: CPC is common incidental finding on imaging studies in older patients (~ 40% prevalence)
                                                        • Fetus: CPCs seen in 1-2% of 2nd-trimester pregnancies

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Maekawa T et al: Choroid plexus cysts analyzed using diffusion-weighted imaging with short diffusion-time. Magn Reson Imaging. 57:323-7, 2019
                                                                                  2. Winter TC et al: How to integrate cell-free DNA screening with sonographic markers for aneuploidy: an update. AJR Am J Roentgenol. 210(4):906-12, 2018
                                                                                  3. Zhang S et al: A retrospective study of cytogenetic results from amniotic fluid in 5328 fetuses with abnormal obstetric sonographic findings. J Ultrasound Med. 36(9):1809-17, 2017
                                                                                  4. Spennato P et al: Acute triventricular hydrocephalus caused by choroid plexus cysts: a diagnostic and neurosurgical challenge. Neurosurg Focus. 41(5):E9, 2016
                                                                                  5. de Lara D et al: Endoscopic treatment of a third ventricle choroid plexus cyst. Neurosurg Focus. 34(1 Suppl):Video 9, 2013
                                                                                  6. Moreau E et al: Incidental bilateral xanthogranuloma of the lateral ventricles at autopsy--a case report. J Forensic Leg Med. 20(6):647-9, 2013
                                                                                  7. Norton KI et al: Prevalence of choroid plexus cysts in term and near-term infants with congenital heart disease. AJR Am J Roentgenol. 196(3):W326-9, 2011
                                                                                  8. Peltier J et al: [Rare tumors of the lateral ventricle. Review of the literature.] Neurochirurgie. 57(4-6):225-9, 2011
                                                                                  9. Naeini RM et al: Spectrum of choroid plexus lesions in children. AJR Am J Roentgenol. 192(1):32-40, 2009
                                                                                  10. Herman TE et al: Aicardi syndrome choroid plexus cysts. J Perinatol. 27(5):323-4, 2007
                                                                                  11. Kinoshita T et al: Clinically silent choroid plexus cyst: evaluation by diffusion-weighted MRI. Neuroradiology. 47(4):251-5, 2005