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Choroid Plexus Cyst
Roya Sohaey, MD
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Clinical Issues

        • Diagnostic Checklist

          TERMINOLOGY

          • Abbreviations

            • Choroid plexus cyst (CPC)
          • Definitions

            • CP: Network of capillaries and specialized ependymal cells in cerebral ventricles that produce cerebrospinal fluid (CSF)
            • CPCs occur when CSF is entrapped in choroid plexus (CP)
              • CPCs are pseudocysts, without epithelial walls

          IMAGING

          • General Features

            • Ultrasonographic Findings

              • Imaging Recommendations

                DIFFERENTIAL DIAGNOSIS

                  PATHOLOGY

                  • General Features

                    CLINICAL ISSUES

                    • Presentation

                      • Demographics

                        • Natural History & Prognosis

                          • Treatment

                            DIAGNOSTIC CHECKLIST

                            • Consider

                              Selected References

                              1. Roee B et al: Subtle findings on fetal brain imaging in CMV infected pregnancies: what is the clinical significance? A retrospective analysis with outcome correlation. Prenat Diagn. ePub, 2019
                              2. Yhoshu E et al: Choroid plexus cysts-antenatal course and postnatal outcome in a tertiary hospital in North India. Childs Nerv Syst. 34(12):2449-53, 2018
                              3. Zhang S et al: A retrospective study of cytogenetic results from amniotic fluid in 5328 fetuses with abnormal obstetric sonographic findings. J Ultrasound Med. 36(9):1809-17, 2017
                              4. Reddy UM et al: Fetal imaging: executive summary of a joint Eunice Kennedy Shriver National Institute of Child Health and Human Development, Society for Maternal-Fetal Medicine, American Institute of Ultrasound in Medicine, American College of Obstetricians and Gynecologists, American College of Radiology, Society for Pediatric Radiology, and Society of Radiologists in Ultrasound Fetal Imaging Workshop. J Ultrasound Med. 33(5):745-57, 2014
                              5. Sonek J et al: Second trimester ultrasound markers of fetal aneuploidy. Clin Obstet Gynecol. 57(1):159-81, 2014
                              6. DiPietro JA et al: Isolated prenatal choroid plexus cysts do not affect child development. Prenat Diagn. 31(8):745-9, 2011
                              7. Rochon M et al: Controversial ultrasound findings. Obstet Gynecol Clin North Am. 31(1):61-99, 2004
                              8. Sahinoglu Z et al: Second trimester choroid plexus cysts and trisomy 18. Int J Gynaecol Obstet. 85(1):24-9, 2004
                              9. Souter VL et al: Correlation of second-trimester sonography and biochemical markers. Obstet Gynecol Surv. 59(11):758-60, 2004
                              10. Turner SR et al: Sonography of fetal choroid plexus cysts: detection depends on cyst size and gestational age. J Ultrasound Med. 22(11):1219-27, 2003
                              11. Kraus I et al: Some observations of the structure of the choroid plexus and its cysts. Prenat Diagn. 22(13):1223-8, 2002
                              12. Ghidini A et al: Isolated fetal choroid plexus cysts: role of ultrasonography in establishment of the risk of trisomy 18. Am J Obstet Gynecol. 182(4):972-7, 2000
                              13. Chitty LS et al: The significance of choroid plexus cysts in an unselected population: results of a multicenter study. Ultrasound Obstet Gynecol. 12(6):391-7, 1998
                              14. Gupta JK et al: Clinical significance of fetal choroid plexus cysts. Lancet. 346(8977):724-9, 1995
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              KEY FACTS

                              • Imaging

                                • Top Differential Diagnoses

                                  • Clinical Issues

                                    • Diagnostic Checklist

                                      TERMINOLOGY

                                      • Abbreviations

                                        • Choroid plexus cyst (CPC)
                                      • Definitions

                                        • CP: Network of capillaries and specialized ependymal cells in cerebral ventricles that produce cerebrospinal fluid (CSF)
                                        • CPCs occur when CSF is entrapped in choroid plexus (CP)
                                          • CPCs are pseudocysts, without epithelial walls

                                      IMAGING

                                      • General Features

                                        • Ultrasonographic Findings

                                          • Imaging Recommendations

                                            DIFFERENTIAL DIAGNOSIS

                                              PATHOLOGY

                                              • General Features

                                                CLINICAL ISSUES

                                                • Presentation

                                                  • Demographics

                                                    • Natural History & Prognosis

                                                      • Treatment

                                                        DIAGNOSTIC CHECKLIST

                                                        • Consider

                                                          Selected References

                                                          1. Roee B et al: Subtle findings on fetal brain imaging in CMV infected pregnancies: what is the clinical significance? A retrospective analysis with outcome correlation. Prenat Diagn. ePub, 2019
                                                          2. Yhoshu E et al: Choroid plexus cysts-antenatal course and postnatal outcome in a tertiary hospital in North India. Childs Nerv Syst. 34(12):2449-53, 2018
                                                          3. Zhang S et al: A retrospective study of cytogenetic results from amniotic fluid in 5328 fetuses with abnormal obstetric sonographic findings. J Ultrasound Med. 36(9):1809-17, 2017
                                                          4. Reddy UM et al: Fetal imaging: executive summary of a joint Eunice Kennedy Shriver National Institute of Child Health and Human Development, Society for Maternal-Fetal Medicine, American Institute of Ultrasound in Medicine, American College of Obstetricians and Gynecologists, American College of Radiology, Society for Pediatric Radiology, and Society of Radiologists in Ultrasound Fetal Imaging Workshop. J Ultrasound Med. 33(5):745-57, 2014
                                                          5. Sonek J et al: Second trimester ultrasound markers of fetal aneuploidy. Clin Obstet Gynecol. 57(1):159-81, 2014
                                                          6. DiPietro JA et al: Isolated prenatal choroid plexus cysts do not affect child development. Prenat Diagn. 31(8):745-9, 2011
                                                          7. Rochon M et al: Controversial ultrasound findings. Obstet Gynecol Clin North Am. 31(1):61-99, 2004
                                                          8. Sahinoglu Z et al: Second trimester choroid plexus cysts and trisomy 18. Int J Gynaecol Obstet. 85(1):24-9, 2004
                                                          9. Souter VL et al: Correlation of second-trimester sonography and biochemical markers. Obstet Gynecol Surv. 59(11):758-60, 2004
                                                          10. Turner SR et al: Sonography of fetal choroid plexus cysts: detection depends on cyst size and gestational age. J Ultrasound Med. 22(11):1219-27, 2003
                                                          11. Kraus I et al: Some observations of the structure of the choroid plexus and its cysts. Prenat Diagn. 22(13):1223-8, 2002
                                                          12. Ghidini A et al: Isolated fetal choroid plexus cysts: role of ultrasonography in establishment of the risk of trisomy 18. Am J Obstet Gynecol. 182(4):972-7, 2000
                                                          13. Chitty LS et al: The significance of choroid plexus cysts in an unselected population: results of a multicenter study. Ultrasound Obstet Gynecol. 12(6):391-7, 1998
                                                          14. Gupta JK et al: Clinical significance of fetal choroid plexus cysts. Lancet. 346(8977):724-9, 1995