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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Chronic lymphocytic leukemia (CLL)
Definitions
- Lymphadenopathy, organomegaly, and infiltrating monoclonal B cells
- Small lymphocytic lymphoma (SLL): Same as CLL with identical immunophenotype and histopathology but lacks peripheral lymphocytosis
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Mauro FR et al: Diagnostic and prognostic role of PET/CT in patients with chronic lymphocytic leukemia and progressive disease. Leukemia. ePub, 2015
- Fiz F et al: Adult advanced chronic lymphocytic leukemia: computational analysis of whole-body CT documents a bone structure alteration. Radiology. 271(3):805-13, 2014
- Gentile M et al: Total body computed tomography scan in the initial work-up of Binet stage A chronic lymphocytic leukemia patients: Results of the prospective, multicenter O-CLL1-GISL study. Am J Hematol. 88(7):539-44, 2013
- Landau DA et al: Chronic lymphocytic leukemia: molecular heterogeneity revealed by high-throughput genomics. Genome Med. 5(5):47, 2013
- Hill BT et al: Pulmonary involvement by chronic lymphocytic leukemia/small lymphocytic lymphoma is a specific pathologic finding independent of inflammatory infiltration. Leuk Lymphoma. 53(4):589-95, 2012
- Santos FP et al: Small lymphocytic lymphoma and chronic lymphocytic leukemia: are they the same disease? Cancer J. 18(5):396-403, 2012
- Moreno C et al: Autoimmune cytopenia in chronic lymphocytic leukemia: prevalence, clinical associations, and prognostic significance. Blood. 116(23):4771-6, 2010
- Tsimberidou AM et al: Assessment of chronic lymphocytic leukemia and small lymphocytic lymphoma by absolute lymphocyte counts in 2,126 patients: 20 years of experience at the University of Texas M.D. Anderson Cancer Center. J Clin Oncol. 25(29):4648-56, 2007
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Chronic lymphocytic leukemia (CLL)
Definitions
- Lymphadenopathy, organomegaly, and infiltrating monoclonal B cells
- Small lymphocytic lymphoma (SLL): Same as CLL with identical immunophenotype and histopathology but lacks peripheral lymphocytosis
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Mauro FR et al: Diagnostic and prognostic role of PET/CT in patients with chronic lymphocytic leukemia and progressive disease. Leukemia. ePub, 2015
- Fiz F et al: Adult advanced chronic lymphocytic leukemia: computational analysis of whole-body CT documents a bone structure alteration. Radiology. 271(3):805-13, 2014
- Gentile M et al: Total body computed tomography scan in the initial work-up of Binet stage A chronic lymphocytic leukemia patients: Results of the prospective, multicenter O-CLL1-GISL study. Am J Hematol. 88(7):539-44, 2013
- Landau DA et al: Chronic lymphocytic leukemia: molecular heterogeneity revealed by high-throughput genomics. Genome Med. 5(5):47, 2013
- Hill BT et al: Pulmonary involvement by chronic lymphocytic leukemia/small lymphocytic lymphoma is a specific pathologic finding independent of inflammatory infiltration. Leuk Lymphoma. 53(4):589-95, 2012
- Santos FP et al: Small lymphocytic lymphoma and chronic lymphocytic leukemia: are they the same disease? Cancer J. 18(5):396-403, 2012
- Moreno C et al: Autoimmune cytopenia in chronic lymphocytic leukemia: prevalence, clinical associations, and prognostic significance. Blood. 116(23):4771-6, 2010
- Tsimberidou AM et al: Assessment of chronic lymphocytic leukemia and small lymphocytic lymphoma by absolute lymphocyte counts in 2,126 patients: 20 years of experience at the University of Texas M.D. Anderson Cancer Center. J Clin Oncol. 25(29):4648-56, 2007
