Progressive, irreversible inflammatory damage to pancreas resulting in parenchymal fibrosis, morphologic changes, and loss of endocrine/exocrine function
IMAGING
General Features
CT Findings
MR Findings
Nuclear Medicine Findings
Radiographic Findings
Ultrasonographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Kamat R et al: Imaging in chronic pancreatitis: state of the art review. Indian J Radiol Imaging. 29(2):201-10, 2019
Singh VK et al: Diagnosis and management of chronic pancreatitis: a review. JAMA. 322(24):2422-34, 2019
Tirkes T et al: Reporting standards for chronic pancreatitis by using CT, MRI, and MR cholangiopancreatography: the consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer. Radiology. 290(1):207-15, 2019
Wolske KM et al: Chronic pancreatitis or pancreatic tumor? A problem-solving approach. Radiographics. 39(7):1965-82, 2019
Parekh D et al: Surgical management of chronic pancreatitis. Indian J Surg. 77(5):453-69, 2015
Gupte AR et al: Chronic pancreatitis. Curr Opin Gastroenterol. 30(5):500-5, 2014
Manikkavasakar S et al: Magnetic resonance imaging of pancreatitis: an update. World J Gastroenterol. 20(40):14760-77, 2014
O'Neill E et al: MR imaging of the pancreas. Radiol Clin North Am. 52(4):757-77, 2014
Raman SP et al: Endoscopic ultrasound and pancreatic applications: what the radiologist needs to know. Abdom Imaging. 38(6):1360-72, 2013
Tirkes T et al: Secretin-enhanced MR cholangiopancreatography: spectrum of findings. Radiographics. 33(7):1889-906, 2013
Arikawa S et al: Assessment of chronic pancreatitis: use of whole pancreas perfusion with 256-slice computed tomography. Pancreas. 41(4):535-40, 2012
Zamboni GA et al: Dynamic MDCT of the pancreas: is time-density curve morphology useful for the differential diagnosis of solid lesions? A preliminary report. Eur J Radiol. 81(3):e381-5, 2012
Lu N et al: 64-slice CT perfusion imaging of pancreatic adenocarcinoma and mass-forming chronic pancreatitis. Acad Radiol. 18(1):81-8, 2011
Andersson R et al: Pathogenesis of chronic pancreatitis: a comprehensive update and a look into the future. Scand J Gastroenterol. 44(6):661-3, 2009
Aoun E et al: Pathways to injury in chronic pancreatitis: decoding the role of the high-risk SPINK1 N34S haplotype using meta-analysis. PLoS ONE. 3(4):e2003, 2008
Aoun E et al: Rapid evolution from the first episode of acute pancreatitis to chronic pancreatitis in human subjects. JOP. 8(5):573-8, 2007
Fink EN et al: Genetic counseling for nonsyndromic pancreatitis. Gastroenterol Clin North Am. 36(2):325-33, ix, 2007
Tamura R et al: Chronic pancreatitis: MRCP versus ERCP for quantitative caliber measurement and qualitative evaluation. Radiology. 238(3):920-8, 2006
Park MS et al: Differentiation of extrahepatic bile duct cholangiocarcinoma from benign stricture: findings at MRCP versus ERCP. Radiology. 233(1):234-40, 2004
Manfredi R et al: Idiopathic chronic pancreatitis in children: MR cholangiopancreatography after secretin administration. Radiology. 224(3):675-82, 2002
Matos C et al: MR imaging of the pancreas: a pictorial tour. Radiographics. 22(1):e2, 2002
Remer EM et al: Imaging of chronic pancreatitis. Radiol Clin North Am. 40(6):1229-42, v, 2002
Varghese JC et al: Value of MR pancreatography in the evaluation of patients with chronic pancreatitis. Clin Radiol. 57(5):393-401, 2002
Ichikawa T et al: Duct-penetrating sign at MRCP: usefulness for differentiating inflammatory pancreatic mass from pancreatic carcinomas. Radiology. 221(1):107-16, 2001
Kim T et al: Pancreatic mass due to chronic pancreatitis: correlation of CT and MR imaging features with pathologic findings. AJR Am J Roentgenol. 177(2):367-71, 2001
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References
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Tables
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Definitions
Progressive, irreversible inflammatory damage to pancreas resulting in parenchymal fibrosis, morphologic changes, and loss of endocrine/exocrine function
IMAGING
General Features
CT Findings
MR Findings
Nuclear Medicine Findings
Radiographic Findings
Ultrasonographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Kamat R et al: Imaging in chronic pancreatitis: state of the art review. Indian J Radiol Imaging. 29(2):201-10, 2019
Singh VK et al: Diagnosis and management of chronic pancreatitis: a review. JAMA. 322(24):2422-34, 2019
Tirkes T et al: Reporting standards for chronic pancreatitis by using CT, MRI, and MR cholangiopancreatography: the consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer. Radiology. 290(1):207-15, 2019
Wolske KM et al: Chronic pancreatitis or pancreatic tumor? A problem-solving approach. Radiographics. 39(7):1965-82, 2019
Parekh D et al: Surgical management of chronic pancreatitis. Indian J Surg. 77(5):453-69, 2015
Gupte AR et al: Chronic pancreatitis. Curr Opin Gastroenterol. 30(5):500-5, 2014
Manikkavasakar S et al: Magnetic resonance imaging of pancreatitis: an update. World J Gastroenterol. 20(40):14760-77, 2014
O'Neill E et al: MR imaging of the pancreas. Radiol Clin North Am. 52(4):757-77, 2014
Raman SP et al: Endoscopic ultrasound and pancreatic applications: what the radiologist needs to know. Abdom Imaging. 38(6):1360-72, 2013
Tirkes T et al: Secretin-enhanced MR cholangiopancreatography: spectrum of findings. Radiographics. 33(7):1889-906, 2013
Arikawa S et al: Assessment of chronic pancreatitis: use of whole pancreas perfusion with 256-slice computed tomography. Pancreas. 41(4):535-40, 2012
Zamboni GA et al: Dynamic MDCT of the pancreas: is time-density curve morphology useful for the differential diagnosis of solid lesions? A preliminary report. Eur J Radiol. 81(3):e381-5, 2012
Lu N et al: 64-slice CT perfusion imaging of pancreatic adenocarcinoma and mass-forming chronic pancreatitis. Acad Radiol. 18(1):81-8, 2011
Andersson R et al: Pathogenesis of chronic pancreatitis: a comprehensive update and a look into the future. Scand J Gastroenterol. 44(6):661-3, 2009
Aoun E et al: Pathways to injury in chronic pancreatitis: decoding the role of the high-risk SPINK1 N34S haplotype using meta-analysis. PLoS ONE. 3(4):e2003, 2008
Aoun E et al: Rapid evolution from the first episode of acute pancreatitis to chronic pancreatitis in human subjects. JOP. 8(5):573-8, 2007
Fink EN et al: Genetic counseling for nonsyndromic pancreatitis. Gastroenterol Clin North Am. 36(2):325-33, ix, 2007
Tamura R et al: Chronic pancreatitis: MRCP versus ERCP for quantitative caliber measurement and qualitative evaluation. Radiology. 238(3):920-8, 2006
Park MS et al: Differentiation of extrahepatic bile duct cholangiocarcinoma from benign stricture: findings at MRCP versus ERCP. Radiology. 233(1):234-40, 2004
Manfredi R et al: Idiopathic chronic pancreatitis in children: MR cholangiopancreatography after secretin administration. Radiology. 224(3):675-82, 2002
Matos C et al: MR imaging of the pancreas: a pictorial tour. Radiographics. 22(1):e2, 2002
Remer EM et al: Imaging of chronic pancreatitis. Radiol Clin North Am. 40(6):1229-42, v, 2002
Varghese JC et al: Value of MR pancreatography in the evaluation of patients with chronic pancreatitis. Clin Radiol. 57(5):393-401, 2002
Ichikawa T et al: Duct-penetrating sign at MRCP: usefulness for differentiating inflammatory pancreatic mass from pancreatic carcinomas. Radiology. 221(1):107-16, 2001
Kim T et al: Pancreatic mass due to chronic pancreatitis: correlation of CT and MR imaging features with pathologic findings. AJR Am J Roentgenol. 177(2):367-71, 2001
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