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Chronic Traumatic Encephalopathy
Anne G. Osborn, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Chronic traumatic encephalopathy (CTE)
          • Synonyms

            • Dementia pugilistica
              • Old term originally applied to boxer's dementia
            • "Punch-drunk" syndrome
            • Postconcussion syndrome
          • Definitions

            • Neurodegenerative disease induced by repetitive concussive and subconcussive head injuries

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Nuclear Medicine Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              Selected References

                              1. Bramlett H et al: Long-Term Consequences of Traumatic Brain Injury: Current Status of Potential Mechanisms of Injury and Neurologic Outcomes. J Neurotrauma. ePub, 2014
                              2. Esopenko C et al: Aging, neurodegenerative disease and traumatic brain injury: the role of neuroimaging. J Neurotrauma. ePub, 2014
                              3. Gandy S et al: Chronic traumatic encephalopathy: clinical-biomarker correlations and current concepts in pathogenesis. Mol Neurodegener. 9:37, 2014
                              4. Sundman MH et al: Examining the relationship between head trauma and neurodegenerative disease: A review of epidemiology, pathology and neuroimaging techniques. J Alzheimers Dis Parkinsonism. 4, 2014
                              5. Aungst SL et al: Repeated mild traumatic brain injury causes chronic neuroinflammation, changes in hippocampal synaptic plasticity, and associated cognitive deficits. J Cereb Blood Flow Metab. 34(7):1223-32, 2014
                              6. Saigal R et al: The Long-term Effects of Repetitive Mild Head Injuries in Sports. Neurosurgery. 75 Suppl 4:S149-55, 2014
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              KEY FACTS

                              • Terminology

                                • Imaging

                                  • Pathology

                                    • Clinical Issues

                                      TERMINOLOGY

                                      • Abbreviations

                                        • Chronic traumatic encephalopathy (CTE)
                                      • Synonyms

                                        • Dementia pugilistica
                                          • Old term originally applied to boxer's dementia
                                        • "Punch-drunk" syndrome
                                        • Postconcussion syndrome
                                      • Definitions

                                        • Neurodegenerative disease induced by repetitive concussive and subconcussive head injuries

                                      IMAGING

                                      • General Features

                                        • CT Findings

                                          • MR Findings

                                            • Nuclear Medicine Findings

                                              • Imaging Recommendations

                                                DIFFERENTIAL DIAGNOSIS

                                                  PATHOLOGY

                                                  • General Features

                                                    • Gross Pathologic & Surgical Features

                                                      • Microscopic Features

                                                        CLINICAL ISSUES

                                                        • Presentation

                                                          Selected References

                                                          1. Bramlett H et al: Long-Term Consequences of Traumatic Brain Injury: Current Status of Potential Mechanisms of Injury and Neurologic Outcomes. J Neurotrauma. ePub, 2014
                                                          2. Esopenko C et al: Aging, neurodegenerative disease and traumatic brain injury: the role of neuroimaging. J Neurotrauma. ePub, 2014
                                                          3. Gandy S et al: Chronic traumatic encephalopathy: clinical-biomarker correlations and current concepts in pathogenesis. Mol Neurodegener. 9:37, 2014
                                                          4. Sundman MH et al: Examining the relationship between head trauma and neurodegenerative disease: A review of epidemiology, pathology and neuroimaging techniques. J Alzheimers Dis Parkinsonism. 4, 2014
                                                          5. Aungst SL et al: Repeated mild traumatic brain injury causes chronic neuroinflammation, changes in hippocampal synaptic plasticity, and associated cognitive deficits. J Cereb Blood Flow Metab. 34(7):1223-32, 2014
                                                          6. Saigal R et al: The Long-term Effects of Repetitive Mild Head Injuries in Sports. Neurosurgery. 75 Suppl 4:S149-55, 2014