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KEY FACTS
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
- Chronic liver disease characterized by diffuse parenchymal necrosis with extensive fibrosis & regenerative nodule formation
- Common end response of liver to variety of insults & injuries
- Chronic liver disease characterized by diffuse parenchymal necrosis with extensive fibrosis & regenerative nodule formation
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Elastographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Kennedy P et al: Quantitative elastography methods in liver disease: current evidence and future directions. Radiology. 286(3):738-63, 2018
- Horowitz JM et al: Evaluation of hepatic fibrosis: a review from the society of abdominal radiology disease focus panel. Abdom Radiol (NY). 42(8):2037-53, 2017
- Srinivasa Babu A et al: Elastography in chronic liver disease: modalities, techniques, limitations, and future directions. Radiographics. 36(7):1987-2006, 2016
- Barr RG et al: Elastography assessment of liver fibrosis: Society of Radiologists in Ultrasound Consensus Conference Statement. Radiology. 276(3):845-61, 2015
- Beland MD et al: A pilot study estimating liver fibrosis with ultrasound shear-wave elastography: does the cause of liver disease or location of measurement affect performance? AJR Am J Roentgenol. 203(3):W267-73, 2014
- Ferraioli G et al: Shear wave elastography for evaluation of liver fibrosis. J Ultrasound Med. 33(2):197-203, 2014
- Buadu A et al: Small liver nodule detection with a high-frequency transducer in patients with chronic liver disease: report of 3 cases. J Ultrasound Med. 32(2):355-9, 2013
- Irshad A et al: Current role of ultrasound in chronic liver disease: surveillance, diagnosis and management of hepatic neoplasms. Curr Probl Diagn Radiol. 41(2):43-51, 2012
- Ridolfi F et al: Contrast-enhanced ultrasound evaluation of hepatic microvascular changes in liver diseases. World J Gastroenterol. 18(37):5225-30, 2012
- Shi Y et al: Quantitative diagnosis of early-stage liver cirrhosis with contrast-enhanced ultrasound--a clinical study. Adv Clin Exp Med. 21(3):385-90, 2012
- Friedrich-Rust M et al: Liver fibrosis in viral hepatitis: noninvasive assessment with acoustic radiation force impulse imaging versus transient elastography. Radiology. 252(2):595-604, 2009
- Goyal N et al: Non-invasive evaluation of liver cirrhosis using ultrasound. Clin Radiol. 64(11):1056-66, 2009
- Vessal S et al: Hepatic vein morphology: a new sonographic diagnostic parameter in the investigation of cirrhosis? J Ultrasound Med. 28(9):1219-27, 2009
- Haktanir A et al: Value of Doppler sonography in assessing the progression of chronic viral hepatitis and in the diagnosis and grading of cirrhosis. J Ultrasound Med. 24(3):311-21, 2005
- Nicolau C et al: Gray-scale ultrasound in hepatic cirrhosis and chronic hepatitis: diagnosis, screening, and intervention. Semin Ultrasound CT MR. 23(1):3-18, 2002
- Tchelepi H et al: Sonography of diffuse liver disease. J Ultrasound Med. 21(9):1023-32; quiz 1033-4, 2002
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References
Tables
Tables
KEY FACTS
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
- Chronic liver disease characterized by diffuse parenchymal necrosis with extensive fibrosis & regenerative nodule formation
- Common end response of liver to variety of insults & injuries
- Chronic liver disease characterized by diffuse parenchymal necrosis with extensive fibrosis & regenerative nodule formation
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Elastographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Kennedy P et al: Quantitative elastography methods in liver disease: current evidence and future directions. Radiology. 286(3):738-63, 2018
- Horowitz JM et al: Evaluation of hepatic fibrosis: a review from the society of abdominal radiology disease focus panel. Abdom Radiol (NY). 42(8):2037-53, 2017
- Srinivasa Babu A et al: Elastography in chronic liver disease: modalities, techniques, limitations, and future directions. Radiographics. 36(7):1987-2006, 2016
- Barr RG et al: Elastography assessment of liver fibrosis: Society of Radiologists in Ultrasound Consensus Conference Statement. Radiology. 276(3):845-61, 2015
- Beland MD et al: A pilot study estimating liver fibrosis with ultrasound shear-wave elastography: does the cause of liver disease or location of measurement affect performance? AJR Am J Roentgenol. 203(3):W267-73, 2014
- Ferraioli G et al: Shear wave elastography for evaluation of liver fibrosis. J Ultrasound Med. 33(2):197-203, 2014
- Buadu A et al: Small liver nodule detection with a high-frequency transducer in patients with chronic liver disease: report of 3 cases. J Ultrasound Med. 32(2):355-9, 2013
- Irshad A et al: Current role of ultrasound in chronic liver disease: surveillance, diagnosis and management of hepatic neoplasms. Curr Probl Diagn Radiol. 41(2):43-51, 2012
- Ridolfi F et al: Contrast-enhanced ultrasound evaluation of hepatic microvascular changes in liver diseases. World J Gastroenterol. 18(37):5225-30, 2012
- Shi Y et al: Quantitative diagnosis of early-stage liver cirrhosis with contrast-enhanced ultrasound--a clinical study. Adv Clin Exp Med. 21(3):385-90, 2012
- Friedrich-Rust M et al: Liver fibrosis in viral hepatitis: noninvasive assessment with acoustic radiation force impulse imaging versus transient elastography. Radiology. 252(2):595-604, 2009
- Goyal N et al: Non-invasive evaluation of liver cirrhosis using ultrasound. Clin Radiol. 64(11):1056-66, 2009
- Vessal S et al: Hepatic vein morphology: a new sonographic diagnostic parameter in the investigation of cirrhosis? J Ultrasound Med. 28(9):1219-27, 2009
- Haktanir A et al: Value of Doppler sonography in assessing the progression of chronic viral hepatitis and in the diagnosis and grading of cirrhosis. J Ultrasound Med. 24(3):311-21, 2005
- Nicolau C et al: Gray-scale ultrasound in hepatic cirrhosis and chronic hepatitis: diagnosis, screening, and intervention. Semin Ultrasound CT MR. 23(1):3-18, 2002
- Tchelepi H et al: Sonography of diffuse liver disease. J Ultrasound Med. 21(9):1023-32; quiz 1033-4, 2002
