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KEY FACTS
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Definitions
Mass consisting of group of 1- to 7-mm cysts with thin (< 0.5 mm), intervening septa
No solid component
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
Imaging Recommendations
Image-Guided Biopsy
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Greenwood HI et al: Clustered microcysts on breast ultrasound: What is the appropriate management? AJR Am J Roentgenol 209:W1-W5, 2017
Mendelson EB et al. ACR BI-RADS Ultrasound. ACR BI-RADS Atlas, Breast Imaging Reporting and Data System. Reston, VA: American College of Radiology, 2013
Berg WA et al: Cystic breast masses and the ACRIN 6666 experience. Radiol Clin North Am. 48(5):931-87, 2010
Daly CP et al: Complicated breast cysts on sonography: is aspiration necessary to exclude malignancy? Acad Radiol. 15(5):610-7, 2008
Chang YW et al: Sonographic differentiation of benign and malignant cystic lesions of the breast. J Ultrasound Med. 26(1):47-53, 2007
Berg WA: Sonographically depicted breast clustered microcysts: is follow-up appropriate? AJR Am J Roentgenol. 185(4):952-9, 2005
Berg WA: Breast ultrasonography: cystic lesions and probably benign findings. In Berg WA et al: Women's Imaging: Strategies for Clinical Practice--Categorical Course Syllabus. Leesburg: American Roentgen Ray Society. 95-102, 2004
Berg WA et al: Cystic lesions of the breast: sonographic-pathologic correlation. Radiology. 227(1):183-91, 2003
Kushwaha AC et al: Mammographic-pathologic correlation of apocrine metaplasia diagnosed using vacuum-assisted stereotactic core-needle biopsy: our 4-year experience. AJR Am J Roentgenol. 180(3):795-8, 2003
Szopinski KT et al: Tissue harmonic imaging: utility in breast sonography. J Ultrasound Med. 22(5):479-87; quiz 488- 9, 2003
Seo BK et al: Sonographic evaluation of breast nodules: comparison of conventional, real-time compound, and pulse-inversion harmonic images. Korean J Radiol. 3(1):38-44, 2002
Mendelson EB et al: Toward a standardized breast ultrasound lexicon, BI-RADS: ultrasound. Semin Roentgenol. 36(3):217-25, 2001
Moy L et al: The pendent view: An additional projection to confirm the diagnosis of milk-of-calcium. AJR. 177:173-5, 2001
Margolin FR et al: Microcystic calcifications at stereotactic breast biopsy. Breast J. 5(3):182-185, 1999
Venta LA et al: Management of complex breast cysts. AJR Am J Roentgenol. 173(5):1331-6, 1999
Warner JK et al: Apocrine metaplasia: mammographic and sonographic appearances. AJR Am J Roentgenol. 170(5):1375-9, 1998
Linden SS et al: Sedimented calcium in benign breast cysts: the full spectrum of mammographic presentations. AJR Am J Roentgenol. 152(5):967-71, 1989
Wellings SR et al: An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. J Natl Cancer Inst. 55(2):231-73, 1975
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Definitions
Mass consisting of group of 1- to 7-mm cysts with thin (< 0.5 mm), intervening septa
No solid component
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
Imaging Recommendations
Image-Guided Biopsy
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Greenwood HI et al: Clustered microcysts on breast ultrasound: What is the appropriate management? AJR Am J Roentgenol 209:W1-W5, 2017
Mendelson EB et al. ACR BI-RADS Ultrasound. ACR BI-RADS Atlas, Breast Imaging Reporting and Data System. Reston, VA: American College of Radiology, 2013
Berg WA et al: Cystic breast masses and the ACRIN 6666 experience. Radiol Clin North Am. 48(5):931-87, 2010
Daly CP et al: Complicated breast cysts on sonography: is aspiration necessary to exclude malignancy? Acad Radiol. 15(5):610-7, 2008
Chang YW et al: Sonographic differentiation of benign and malignant cystic lesions of the breast. J Ultrasound Med. 26(1):47-53, 2007
Berg WA: Sonographically depicted breast clustered microcysts: is follow-up appropriate? AJR Am J Roentgenol. 185(4):952-9, 2005
Berg WA: Breast ultrasonography: cystic lesions and probably benign findings. In Berg WA et al: Women's Imaging: Strategies for Clinical Practice--Categorical Course Syllabus. Leesburg: American Roentgen Ray Society. 95-102, 2004
Berg WA et al: Cystic lesions of the breast: sonographic-pathologic correlation. Radiology. 227(1):183-91, 2003
Kushwaha AC et al: Mammographic-pathologic correlation of apocrine metaplasia diagnosed using vacuum-assisted stereotactic core-needle biopsy: our 4-year experience. AJR Am J Roentgenol. 180(3):795-8, 2003
Szopinski KT et al: Tissue harmonic imaging: utility in breast sonography. J Ultrasound Med. 22(5):479-87; quiz 488- 9, 2003
Seo BK et al: Sonographic evaluation of breast nodules: comparison of conventional, real-time compound, and pulse-inversion harmonic images. Korean J Radiol. 3(1):38-44, 2002
Mendelson EB et al: Toward a standardized breast ultrasound lexicon, BI-RADS: ultrasound. Semin Roentgenol. 36(3):217-25, 2001
Moy L et al: The pendent view: An additional projection to confirm the diagnosis of milk-of-calcium. AJR. 177:173-5, 2001
Margolin FR et al: Microcystic calcifications at stereotactic breast biopsy. Breast J. 5(3):182-185, 1999
Venta LA et al: Management of complex breast cysts. AJR Am J Roentgenol. 173(5):1331-6, 1999
Warner JK et al: Apocrine metaplasia: mammographic and sonographic appearances. AJR Am J Roentgenol. 170(5):1375-9, 1998
Linden SS et al: Sedimented calcium in benign breast cysts: the full spectrum of mammographic presentations. AJR Am J Roentgenol. 152(5):967-71, 1989
Wellings SR et al: An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. J Natl Cancer Inst. 55(2):231-73, 1975
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