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Colloid Cyst
Anne G. Osborn, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Colloid cyst (CC)
              • Synonyms

                • Paraphyseal cyst, endodermal cyst
              • Definitions

                • Unilocular, mucin-containing 3rd ventricular cyst

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Alford EN et al: Interrater and intrarater reliability of the Colloid Cyst Risk Score. Neurosurgery. 86(1):E47-53, 2020
                                          2. Alford EN et al: Independent validation of the colloid cyst risk score to predict symptoms and hydrocephalus in patients with colloid cysts of the third ventricle. World Neurosurg. 134:e747-53, 2020
                                          3. Heller RS et al: Colloid cysts: evolution of surgical approach preference and management of recurrent cysts. Oper Neurosurg (Hagerstown). 18(1):19-25, 2020
                                          4. Isaacs AM et al: Long-term outcomes of endoscopic third ventricle colloid cyst resection: case series with a proposed grading system. Oper Neurosurg (Hagerstown). 19(2):134-42, 2020
                                          5. Kutty RK et al: Flying with colloid cyst: a cautionary note. World Neurosurg. 138:84-8, 2020
                                          6. Magalhães-Ribeiro C et al: Spontaneous asymptomatic resolution of a third ventricle colloid cyst. Neurochirurgie. 66(2):137-8, 2020
                                          7. Mulcahy MJ et al: The case of the disappearing colloid cyst. World Neurosurg. 135:100-2, 2020
                                          8. Muscas G et al: Are familial colloid cysts of the third ventricle associated with a worse clinical course than sporadic forms? Case illustration and systematic literature review. J Neurosurg Sci. ePub, 2020
                                          9. Ciappetta P et al: Schwalbe's triangular fossa: normal and pathologic anatomy on frozen cadavers. anatomo-magnetic resonance imaging comparison and surgical implications in colloid cyst surgery. World Neurosurg. 128:e116-28, 2019
                                          10. Cuoco JA et al: Postexercise death due to hemorrhagic colloid cyst of third ventricle: case report and literature review. World Neurosurg. 123:351-6, 2019
                                          11. Al Abdulsalam HK et al: Hemorrhagic colloid cyst. Neurosciences (Riyadh). 23(4):326-33, 2018
                                          12. O'Neill AH et al: Natural history of incidental colloid cysts of the third ventricle: a systematic review. J Clin Neurosci. 53:122-6, 2018
                                          13. Vazhayil V et al: Surgical management of colloid cysts in children: experience at a tertiary care center. Childs Nerv Syst. 34(6):1215-20, 2018
                                          14. Barbagallo GM et al: Out-of-third ventricle colloid cysts: review of the literature on pathophysiology, diagnosis and treatment of an uncommon condition, with a focus on headache. J Neurosurg Sci. 63(3):330-6, 2016
                                          15. Margetis K et al: Endoscopic resection of incidental colloid cysts. J Neurosurg. 120(6):1259-67, 2014
                                          16. Sheikh AB et al: Endoscopic versus microsurgical resection of colloid cysts: a systematic review and meta-analysis of 1,278 patients. World Neurosurg. 82(6):1187-97, 2014
                                          17. Woodley-Cook J et al: Neurosurgical management of a giant colloid cyst with atypical clinical and radiological presentation. J Neurosurg. 121(5):1185-8, 2014
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Colloid cyst (CC)
                                                      • Synonyms

                                                        • Paraphyseal cyst, endodermal cyst
                                                      • Definitions

                                                        • Unilocular, mucin-containing 3rd ventricular cyst

                                                      IMAGING

                                                      • General Features

                                                        • CT Findings

                                                          • MR Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Alford EN et al: Interrater and intrarater reliability of the Colloid Cyst Risk Score. Neurosurgery. 86(1):E47-53, 2020
                                                                                  2. Alford EN et al: Independent validation of the colloid cyst risk score to predict symptoms and hydrocephalus in patients with colloid cysts of the third ventricle. World Neurosurg. 134:e747-53, 2020
                                                                                  3. Heller RS et al: Colloid cysts: evolution of surgical approach preference and management of recurrent cysts. Oper Neurosurg (Hagerstown). 18(1):19-25, 2020
                                                                                  4. Isaacs AM et al: Long-term outcomes of endoscopic third ventricle colloid cyst resection: case series with a proposed grading system. Oper Neurosurg (Hagerstown). 19(2):134-42, 2020
                                                                                  5. Kutty RK et al: Flying with colloid cyst: a cautionary note. World Neurosurg. 138:84-8, 2020
                                                                                  6. Magalhães-Ribeiro C et al: Spontaneous asymptomatic resolution of a third ventricle colloid cyst. Neurochirurgie. 66(2):137-8, 2020
                                                                                  7. Mulcahy MJ et al: The case of the disappearing colloid cyst. World Neurosurg. 135:100-2, 2020
                                                                                  8. Muscas G et al: Are familial colloid cysts of the third ventricle associated with a worse clinical course than sporadic forms? Case illustration and systematic literature review. J Neurosurg Sci. ePub, 2020
                                                                                  9. Ciappetta P et al: Schwalbe's triangular fossa: normal and pathologic anatomy on frozen cadavers. anatomo-magnetic resonance imaging comparison and surgical implications in colloid cyst surgery. World Neurosurg. 128:e116-28, 2019
                                                                                  10. Cuoco JA et al: Postexercise death due to hemorrhagic colloid cyst of third ventricle: case report and literature review. World Neurosurg. 123:351-6, 2019
                                                                                  11. Al Abdulsalam HK et al: Hemorrhagic colloid cyst. Neurosciences (Riyadh). 23(4):326-33, 2018
                                                                                  12. O'Neill AH et al: Natural history of incidental colloid cysts of the third ventricle: a systematic review. J Clin Neurosci. 53:122-6, 2018
                                                                                  13. Vazhayil V et al: Surgical management of colloid cysts in children: experience at a tertiary care center. Childs Nerv Syst. 34(6):1215-20, 2018
                                                                                  14. Barbagallo GM et al: Out-of-third ventricle colloid cysts: review of the literature on pathophysiology, diagnosis and treatment of an uncommon condition, with a focus on headache. J Neurosurg Sci. 63(3):330-6, 2016
                                                                                  15. Margetis K et al: Endoscopic resection of incidental colloid cysts. J Neurosurg. 120(6):1259-67, 2014
                                                                                  16. Sheikh AB et al: Endoscopic versus microsurgical resection of colloid cysts: a systematic review and meta-analysis of 1,278 patients. World Neurosurg. 82(6):1187-97, 2014
                                                                                  17. Woodley-Cook J et al: Neurosurgical management of a giant colloid cyst with atypical clinical and radiological presentation. J Neurosurg. 121(5):1185-8, 2014