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Colon Carcinoma
Michael P. Federle, MD, FACR
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Colorectal carcinoma (CRC)
          • Definitions

            • Malignant transformation of colonic mucosa

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Brenner H et al: Colorectal cancer. Lancet. 383(9927):1490-502, 2014
                                            2. Moldovan R et al: Total necrotizing colitis proximal to obstructive left colon cancer: case report and literature review. Chirurgia (Bucur). 108(3):396-9, 2013
                                            3. Rasool S et al: A comparative overview of general risk factors associated with the incidence of colorectal cancer. Tumour Biol. 34(5):2469-76, 2013
                                            4. Thomassen I et al: Incidence, prognosis, and treatment options for patients with synchronous peritoneal carcinomatosis and liver metastases from colorectal origin. Dis Colon Rectum. 56(12):1373-80, 2013
                                            5. Lee JC et al: The segmental distribution and clinical significance of colorectal fluorodeoxyglucose uptake incidentally detected on PET-CT. Nucl Med Commun. 30(5):333-7, 2009
                                            6. Kosugi C et al: Positron emission tomography for preoperative staging in patients with locally advanced or metastatic colorectal adenocarcinoma in lymph node metastasis. Hepatogastroenterology. 55(82-83):398-402, 2008
                                            7. Ko EY et al: CT differentiation of mucinous and nonmucinous colorectal carcinoma. AJR Am J Roentgenol. 188(3):785-91, 2007
                                            8. Bar-Shalom R et al: Clinical performance of PET/CT in evaluation of cancer: additional value for diagnostic imaging and patient management. J Nucl Med. 44(8):1200-9, 2003
                                            9. Cohade C et al: Direct comparison of (18)F-FDG PET and PET/CT in patients with colorectal carcinoma. J Nucl Med. 44(11):1797-803, 2003
                                            10. Pickhardt PJ et al: Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N Engl J Med. 349(23):2191-200, 2003
                                            11. Kim HJ et al: CT features of primary colorectal signet-ring cell carcinoma. J Comput Assist Tomogr. 25(2):225-30, 2001
                                            12. Gazelle GS et al: Screening for colorectal cancer. Radiology. 215(2):327-35, 2000
                                            13. Horton KM et al: Spiral CT of colon cancer: imaging features and role in management. Radiographics. 20(2):419-30, 2000
                                            14. Levine MS et al: Diagnosis of colorectal neoplasms at double-contrast barium enema examination. Radiology. 216(1):11-8, 2000
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Colorectal carcinoma (CRC)
                                                    • Definitions

                                                      • Malignant transformation of colonic mucosa

                                                    IMAGING

                                                    • General Features

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • MR Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Brenner H et al: Colorectal cancer. Lancet. 383(9927):1490-502, 2014
                                                                                      2. Moldovan R et al: Total necrotizing colitis proximal to obstructive left colon cancer: case report and literature review. Chirurgia (Bucur). 108(3):396-9, 2013
                                                                                      3. Rasool S et al: A comparative overview of general risk factors associated with the incidence of colorectal cancer. Tumour Biol. 34(5):2469-76, 2013
                                                                                      4. Thomassen I et al: Incidence, prognosis, and treatment options for patients with synchronous peritoneal carcinomatosis and liver metastases from colorectal origin. Dis Colon Rectum. 56(12):1373-80, 2013
                                                                                      5. Lee JC et al: The segmental distribution and clinical significance of colorectal fluorodeoxyglucose uptake incidentally detected on PET-CT. Nucl Med Commun. 30(5):333-7, 2009
                                                                                      6. Kosugi C et al: Positron emission tomography for preoperative staging in patients with locally advanced or metastatic colorectal adenocarcinoma in lymph node metastasis. Hepatogastroenterology. 55(82-83):398-402, 2008
                                                                                      7. Ko EY et al: CT differentiation of mucinous and nonmucinous colorectal carcinoma. AJR Am J Roentgenol. 188(3):785-91, 2007
                                                                                      8. Bar-Shalom R et al: Clinical performance of PET/CT in evaluation of cancer: additional value for diagnostic imaging and patient management. J Nucl Med. 44(8):1200-9, 2003
                                                                                      9. Cohade C et al: Direct comparison of (18)F-FDG PET and PET/CT in patients with colorectal carcinoma. J Nucl Med. 44(11):1797-803, 2003
                                                                                      10. Pickhardt PJ et al: Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N Engl J Med. 349(23):2191-200, 2003
                                                                                      11. Kim HJ et al: CT features of primary colorectal signet-ring cell carcinoma. J Comput Assist Tomogr. 25(2):225-30, 2001
                                                                                      12. Gazelle GS et al: Screening for colorectal cancer. Radiology. 215(2):327-35, 2000
                                                                                      13. Horton KM et al: Spiral CT of colon cancer: imaging features and role in management. Radiographics. 20(2):419-30, 2000
                                                                                      14. Levine MS et al: Diagnosis of colorectal neoplasms at double-contrast barium enema examination. Radiology. 216(1):11-8, 2000