link
Bookmarks
Combined Pulmonary Fibrosis and Emphysema
Aletta Ann Frazier, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Subscribe
0
0
3
0

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Combined pulmonary fibrosis and emphysema (CPFE)
              • Definitions

                • Idiopathic pulmonary fibrosis (IPF)/usual interstitial pneumonia (UIP) pattern on background of emphysema
                • Other chronic fibrosing interstitial lung disease (ILD) on background of emphysema
                • Distinct but heterogeneous clinical entity, most often affects current or former heavy smokers

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    • Diagnosis

                                      DIAGNOSTIC CHECKLIST

                                      • Image Interpretation Pearls

                                        • Reporting Tips

                                          Selected References

                                          1. Hage R et al: Combined pulmonary fibrosis and emphysema (CPFE) clinical features and management. Int J Chron Obstruct Pulmon Dis. 16:167-77, 2021
                                          2. Bolaki M et al: Combined pulmonary fibrosis and emphysema. Semin Respir Crit Care Med. 41(2):177-83, 2020
                                          3. Amariei DE et al: Combined pulmonary fibrosis and emphysema: pulmonary function testing and a pathophysiology perspective. Medicina (Kaunas). 55(9), 2019
                                          4. Sousa C et al: Diffuse smoking-related lung diseases: insights from a radiologic-pathologic correlation. Insights Imaging. 10(1):73, 2019
                                          5. Hashimoto N et al: Impact of thin-section computed tomography-determined combined pulmonary fibrosis and emphysema on outcomes among patients with resected lung cancer. Ann Thorac Surg. 102(2):440-7, 2016
                                          6. Lin H et al: Combined pulmonary fibrosis and emphysema (CPFE): an entity different from emphysema or pulmonary fibrosis alone. J Thorac Dis. 7(4):767-79, 2015
                                          7. Choi SH et al: The value of CT for disease detection and prognosis determination in combined pulmonary fibrosis and emphysema (CPFE). PLoS One. 9(9):e107476, 2014
                                          8. Jankowich MD et al: Combined pulmonary fibrosis and emphysema syndrome: a review. Chest. 141(1):222-31, 2012
                                          9. Sakai F et al: Imaging diagnosis of interstitial pneumonia with emphysema (combined pulmonary fibrosis and emphysema). Pulm Med. 2012:816541, 2012
                                          10. Wright JL et al: Fibrosis with emphysema. Histopathology. 58(4):517-24, 2011
                                          11. Chung JH et al: Smoking-related interstitial lung diseases. Semin Roentgenol. 45(1):29-35, 2010
                                          12. Attili AK et al: Smoking-related interstitial lung disease: radiologic-clinical-pathologic correlation. Radiographics. 28(5):1383-96; discussion 1396-8, 2008
                                          13. Rao RN et al: Smoking-related interstitial lung disease. Ann Diagn Pathol. 12(6):445-57, 2008
                                          14. Wells AU et al: Challenges in pulmonary fibrosis. 4: smoking-induced diffuse interstitial lung diseases. Thorax. 62(10):904-10, 2007
                                          15. Hidalgo A et al: Smoking-related interstitial lung diseases: radiologic-pathologic correlation. Eur Radiol. 16(11):2463-70, 2006
                                          16. Remy-Jardin M et al: Lung parenchymal changes secondary to cigarette smoking: pathologic-CT correlations. Radiology. 186(3):643-51, 1993
                                          Related Anatomy
                                          Loading...
                                          Related Differential Diagnoses
                                          Loading...
                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Combined pulmonary fibrosis and emphysema (CPFE)
                                                      • Definitions

                                                        • Idiopathic pulmonary fibrosis (IPF)/usual interstitial pneumonia (UIP) pattern on background of emphysema
                                                        • Other chronic fibrosing interstitial lung disease (ILD) on background of emphysema
                                                        • Distinct but heterogeneous clinical entity, most often affects current or former heavy smokers

                                                      IMAGING

                                                      • General Features

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            • Diagnosis

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Image Interpretation Pearls

                                                                                • Reporting Tips

                                                                                  Selected References

                                                                                  1. Hage R et al: Combined pulmonary fibrosis and emphysema (CPFE) clinical features and management. Int J Chron Obstruct Pulmon Dis. 16:167-77, 2021
                                                                                  2. Bolaki M et al: Combined pulmonary fibrosis and emphysema. Semin Respir Crit Care Med. 41(2):177-83, 2020
                                                                                  3. Amariei DE et al: Combined pulmonary fibrosis and emphysema: pulmonary function testing and a pathophysiology perspective. Medicina (Kaunas). 55(9), 2019
                                                                                  4. Sousa C et al: Diffuse smoking-related lung diseases: insights from a radiologic-pathologic correlation. Insights Imaging. 10(1):73, 2019
                                                                                  5. Hashimoto N et al: Impact of thin-section computed tomography-determined combined pulmonary fibrosis and emphysema on outcomes among patients with resected lung cancer. Ann Thorac Surg. 102(2):440-7, 2016
                                                                                  6. Lin H et al: Combined pulmonary fibrosis and emphysema (CPFE): an entity different from emphysema or pulmonary fibrosis alone. J Thorac Dis. 7(4):767-79, 2015
                                                                                  7. Choi SH et al: The value of CT for disease detection and prognosis determination in combined pulmonary fibrosis and emphysema (CPFE). PLoS One. 9(9):e107476, 2014
                                                                                  8. Jankowich MD et al: Combined pulmonary fibrosis and emphysema syndrome: a review. Chest. 141(1):222-31, 2012
                                                                                  9. Sakai F et al: Imaging diagnosis of interstitial pneumonia with emphysema (combined pulmonary fibrosis and emphysema). Pulm Med. 2012:816541, 2012
                                                                                  10. Wright JL et al: Fibrosis with emphysema. Histopathology. 58(4):517-24, 2011
                                                                                  11. Chung JH et al: Smoking-related interstitial lung diseases. Semin Roentgenol. 45(1):29-35, 2010
                                                                                  12. Attili AK et al: Smoking-related interstitial lung disease: radiologic-clinical-pathologic correlation. Radiographics. 28(5):1383-96; discussion 1396-8, 2008
                                                                                  13. Rao RN et al: Smoking-related interstitial lung disease. Ann Diagn Pathol. 12(6):445-57, 2008
                                                                                  14. Wells AU et al: Challenges in pulmonary fibrosis. 4: smoking-induced diffuse interstitial lung diseases. Thorax. 62(10):904-10, 2007
                                                                                  15. Hidalgo A et al: Smoking-related interstitial lung diseases: radiologic-pathologic correlation. Eur Radiol. 16(11):2463-70, 2006
                                                                                  16. Remy-Jardin M et al: Lung parenchymal changes secondary to cigarette smoking: pathologic-CT correlations. Radiology. 186(3):643-51, 1993