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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Congenital lobar overinflation (CLO)
Synonyms
- Congenital lobar emphysema, congenital lobar hyperinflation, infantile lobar emphysema
Definitions
- Congenital abnormality of lower airways that results in progressive overexpansion of pulmonary lobe
- Considered final, common pathway of various disruptions of bronchopulmonary development
- 50% idiopathic
- 25% due to intrinsic cartilaginous abnormality
- 25% due to extrinsic compression
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
- Krivchenya DU et al: Congenital emphysema in children: segmental lung resection as an alternative to lobectomy. J Pediatr Surg. 48(2):309-14, 2013
- Pacharn P et al: Congenital lung lesions: prenatal MRI and postnatal findings. Pediatr Radiol. 43(9):1136-43, 2013
- Chen IC et al: Usefulness of combination of pulmonary ventilation and perfusion scintigraphy on the diagnosis of children with unilateral hyperlucent lung. Nucl Med Commun. 32(11):1052-9, 2011
- Biyyam DR et al: Congenital lung abnormalities: embryologic features, prenatal diagnosis, and postnatal radiologic-pathologic correlation. Radiographics. 30(6):1721-38, 2010
- Lee EY et al: Multidetector CT evaluation of congenital lung anomalies. Radiology. 247(3):632-48, 2008
- Ulku R et al: Congenital lobar emphysema: differential diagnosis and therapeutic approach. Pediatr Int. 50(5):658-61, 2008
- Berrocal T et al: Congenital anomalies of the tracheobronchial tree, lung, and mediastinum: embryology, radiology, and pathology. Radiographics. 24(1):e17, 2004
- Daltro P et al: CT of congenital lung lesions in pediatric patients. AJR Am J Roentgenol. 183(5):1497-506, 2004
- Ozçelik U et al: Congenital lobar emphysema: evaluation and long-term follow-up of thirty cases at a single center. Pediatr Pulmonol. 35(5):384-91, 2003
- Tander B et al: Congenital lobar emphysema: a clinicopathologic evaluation of 14 cases. Eur J Pediatr Surg. 13(2):108-11, 2003
- Donnelly LF et al: Localized lucent chest lesions in neonates. AJR. 212:837-40, 1999
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Congenital lobar overinflation (CLO)
Synonyms
- Congenital lobar emphysema, congenital lobar hyperinflation, infantile lobar emphysema
Definitions
- Congenital abnormality of lower airways that results in progressive overexpansion of pulmonary lobe
- Considered final, common pathway of various disruptions of bronchopulmonary development
- 50% idiopathic
- 25% due to intrinsic cartilaginous abnormality
- 25% due to extrinsic compression
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
- Krivchenya DU et al: Congenital emphysema in children: segmental lung resection as an alternative to lobectomy. J Pediatr Surg. 48(2):309-14, 2013
- Pacharn P et al: Congenital lung lesions: prenatal MRI and postnatal findings. Pediatr Radiol. 43(9):1136-43, 2013
- Chen IC et al: Usefulness of combination of pulmonary ventilation and perfusion scintigraphy on the diagnosis of children with unilateral hyperlucent lung. Nucl Med Commun. 32(11):1052-9, 2011
- Biyyam DR et al: Congenital lung abnormalities: embryologic features, prenatal diagnosis, and postnatal radiologic-pathologic correlation. Radiographics. 30(6):1721-38, 2010
- Lee EY et al: Multidetector CT evaluation of congenital lung anomalies. Radiology. 247(3):632-48, 2008
- Ulku R et al: Congenital lobar emphysema: differential diagnosis and therapeutic approach. Pediatr Int. 50(5):658-61, 2008
- Berrocal T et al: Congenital anomalies of the tracheobronchial tree, lung, and mediastinum: embryology, radiology, and pathology. Radiographics. 24(1):e17, 2004
- Daltro P et al: CT of congenital lung lesions in pediatric patients. AJR Am J Roentgenol. 183(5):1497-506, 2004
- Ozçelik U et al: Congenital lobar emphysema: evaluation and long-term follow-up of thirty cases at a single center. Pediatr Pulmonol. 35(5):384-91, 2003
- Tander B et al: Congenital lobar emphysema: a clinicopathologic evaluation of 14 cases. Eur J Pediatr Surg. 13(2):108-11, 2003
- Donnelly LF et al: Localized lucent chest lesions in neonates. AJR. 212:837-40, 1999
