link
Bookmarks
Congenital Lobar Overinflation
Hank Baskin, MD
To access 4,300 diagnoses written by the world's leading experts in radiology.Try it free - 15 days
0
4
3
2

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Congenital lobar overinflation (CLO)
            • Synonyms

              • Congenital lobar hyperinflation
              • Congenital lobar emphysema is no longer used, as microscopic analysis shows airspace overinflation, not alveolar destruction
            • Definitions

              • Congenital lung malformation consisting of overdistended pulmonary segment or lobe; caused by partial bronchial obstruction acting as 1-way valve → air-trapping
              • Considered final, common pathway of various disruptions of bronchopulmonary development
                • 50% are idiopathic
                • 25% are due to intrinsic cartilaginous abnormality
                • 25% are due to extrinsic compression

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • Ultrasonographic Findings

                    • MR Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            Selected References

                                            1. Newman B: Magnetic resonance imaging for congenital lung malformations. Pediatr Radiol. ePub, 2021
                                            2. Abdel-Bary M et al: Clinical and surgical aspects of congenital lobar over-inflation: a single center retrospective study. J Cardiothorac Surg. 15(1):102, 2020
                                            3. Bawazir OA: Congenital lobar emphysema: thoracotomy versus minimally invasive surgery. Ann Thorac Med. 15(1):21-25, 2020
                                            4. Oliver ER et al: Congenital lobar overinflation: a rare enigmatic lung lesion on prenatal ultrasound and magnetic resonance imaging. J Ultrasound Med. 38(5):1229-39, 2019
                                            5. Krivchenya DU et al: Congenital emphysema in children: segmental lung resection as an alternative to lobectomy. J Pediatr Surg. 48(2):309-14, 2013
                                            6. Pacharn P et al: Congenital lung lesions: prenatal MRI and postnatal findings. Pediatr Radiol. 43(9):1136-43, 2013
                                            7. Chen IC et al: Usefulness of combination of pulmonary ventilation and perfusion scintigraphy on the diagnosis of children with unilateral hyperlucent lung. Nucl Med Commun. 32(11):1052-9, 2011
                                            8. Biyyam DR et al: Congenital lung abnormalities: embryologic features, prenatal diagnosis, and postnatal radiologic-pathologic correlation. Radiographics. 30(6):1721-38, 2010
                                            9. Lee EY et al: Multidetector CT evaluation of congenital lung anomalies. Radiology. 247(3):632-48, 2008
                                            10. Ulku R et al: Congenital lobar emphysema: differential diagnosis and therapeutic approach. Pediatr Int. 50(5):658-61, 2008
                                            11. Berrocal T et al: Congenital anomalies of the tracheobronchial tree, lung, and mediastinum: embryology, radiology, and pathology. Radiographics. 24(1):e17, 2004
                                            12. Daltro P et al: CT of congenital lung lesions in pediatric patients. AJR Am J Roentgenol. 183(5):1497-506, 2004
                                            13. Ozçelik U et al: Congenital lobar emphysema: evaluation and long-term follow-up of thirty cases at a single center. Pediatr Pulmonol. 35(5):384-91, 2003
                                            14. Tander B et al: Congenital lobar emphysema: a clinicopathologic evaluation of 14 cases. Eur J Pediatr Surg. 13(2):108-11, 2003
                                            15. Donnelly LF et al: Localized lucent chest lesions in neonates. AJR. 212:837-40, 1999
                                            Related Anatomy
                                            Loading...
                                            Related Differential Diagnoses
                                            Loading...
                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Congenital lobar overinflation (CLO)
                                                      • Synonyms

                                                        • Congenital lobar hyperinflation
                                                        • Congenital lobar emphysema is no longer used, as microscopic analysis shows airspace overinflation, not alveolar destruction
                                                      • Definitions

                                                        • Congenital lung malformation consisting of overdistended pulmonary segment or lobe; caused by partial bronchial obstruction acting as 1-way valve → air-trapping
                                                        • Considered final, common pathway of various disruptions of bronchopulmonary development
                                                          • 50% are idiopathic
                                                          • 25% are due to intrinsic cartilaginous abnormality
                                                          • 25% are due to extrinsic compression

                                                      IMAGING

                                                      • General Features

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • Ultrasonographic Findings

                                                              • MR Findings

                                                                • Nuclear Medicine Findings

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Staging, Grading, & Classification

                                                                          • Gross Pathologic & Surgical Features

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      Selected References

                                                                                      1. Newman B: Magnetic resonance imaging for congenital lung malformations. Pediatr Radiol. ePub, 2021
                                                                                      2. Abdel-Bary M et al: Clinical and surgical aspects of congenital lobar over-inflation: a single center retrospective study. J Cardiothorac Surg. 15(1):102, 2020
                                                                                      3. Bawazir OA: Congenital lobar emphysema: thoracotomy versus minimally invasive surgery. Ann Thorac Med. 15(1):21-25, 2020
                                                                                      4. Oliver ER et al: Congenital lobar overinflation: a rare enigmatic lung lesion on prenatal ultrasound and magnetic resonance imaging. J Ultrasound Med. 38(5):1229-39, 2019
                                                                                      5. Krivchenya DU et al: Congenital emphysema in children: segmental lung resection as an alternative to lobectomy. J Pediatr Surg. 48(2):309-14, 2013
                                                                                      6. Pacharn P et al: Congenital lung lesions: prenatal MRI and postnatal findings. Pediatr Radiol. 43(9):1136-43, 2013
                                                                                      7. Chen IC et al: Usefulness of combination of pulmonary ventilation and perfusion scintigraphy on the diagnosis of children with unilateral hyperlucent lung. Nucl Med Commun. 32(11):1052-9, 2011
                                                                                      8. Biyyam DR et al: Congenital lung abnormalities: embryologic features, prenatal diagnosis, and postnatal radiologic-pathologic correlation. Radiographics. 30(6):1721-38, 2010
                                                                                      9. Lee EY et al: Multidetector CT evaluation of congenital lung anomalies. Radiology. 247(3):632-48, 2008
                                                                                      10. Ulku R et al: Congenital lobar emphysema: differential diagnosis and therapeutic approach. Pediatr Int. 50(5):658-61, 2008
                                                                                      11. Berrocal T et al: Congenital anomalies of the tracheobronchial tree, lung, and mediastinum: embryology, radiology, and pathology. Radiographics. 24(1):e17, 2004
                                                                                      12. Daltro P et al: CT of congenital lung lesions in pediatric patients. AJR Am J Roentgenol. 183(5):1497-506, 2004
                                                                                      13. Ozçelik U et al: Congenital lobar emphysema: evaluation and long-term follow-up of thirty cases at a single center. Pediatr Pulmonol. 35(5):384-91, 2003
                                                                                      14. Tander B et al: Congenital lobar emphysema: a clinicopathologic evaluation of 14 cases. Eur J Pediatr Surg. 13(2):108-11, 2003
                                                                                      15. Donnelly LF et al: Localized lucent chest lesions in neonates. AJR. 212:837-40, 1999