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Obstetrics
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Congenital Syphilis
Congenital Syphilis
Roya Sohaey, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Congenital syphilis (CS)

            • Definitions

              • CS caused by sexually transmitted gram-negative spirochete bacterium, Treponema pallidum

            IMAGING

            • General Features

              • Ultrasonographic Findings

                DIFFERENTIAL DIAGNOSIS

                  PATHOLOGY

                  • General Features

                    • Staging, Grading, & Classification

                      • Microscopic Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Natural History & Prognosis

                              • Treatment

                                DIAGNOSTIC CHECKLIST

                                • Consider

                                  • Image Interpretation Pearls

                                    Selected References

                                    1. Jensen KK et al: Fetal hepatomegaly: causes and associations. Radiographics. 40(2):589-604, 2020
                                    2. Rac MWF et al: Congenital syphilis: a contemporary update on an ancient disease. Prenat Diagn. 40(13):1703-14, 2020
                                    3. Tsai S et al: Syphilis in pregnancy. Obstet Gynecol Surv. 74(9):557-64, 2019
                                    4. Kittipornpechdee N et al: Fetal and placental pathology in congenital syphilis: a comprehensive study in perinatal autopsy. Fetal Pediatr Pathol. 1-12, 2018
                                    5. Rac MW et al: Syphilis during pregnancy: a preventable threat to maternal-fetal health. Am J Obstet Gynecol. 216(4):352-63, 2017
                                    6. Vintzileos AM et al: Fetal liver ultrasound measurements during normal pregnancy. Obstet Gynecol. 66(4):477-80, 1985
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            • Diagnostic Checklist

                                              TERMINOLOGY

                                              • Abbreviations

                                                • Congenital syphilis (CS)

                                              • Definitions

                                                • CS caused by sexually transmitted gram-negative spirochete bacterium, Treponema pallidum

                                              IMAGING

                                              • General Features

                                                • Ultrasonographic Findings

                                                  DIFFERENTIAL DIAGNOSIS

                                                    PATHOLOGY

                                                    • General Features

                                                      • Staging, Grading, & Classification

                                                        • Microscopic Features

                                                          CLINICAL ISSUES

                                                          • Presentation

                                                            • Demographics

                                                              • Natural History & Prognosis

                                                                • Treatment

                                                                  DIAGNOSTIC CHECKLIST

                                                                  • Consider

                                                                    • Image Interpretation Pearls

                                                                      Selected References

                                                                      1. Jensen KK et al: Fetal hepatomegaly: causes and associations. Radiographics. 40(2):589-604, 2020
                                                                      2. Rac MWF et al: Congenital syphilis: a contemporary update on an ancient disease. Prenat Diagn. 40(13):1703-14, 2020
                                                                      3. Tsai S et al: Syphilis in pregnancy. Obstet Gynecol Surv. 74(9):557-64, 2019
                                                                      4. Kittipornpechdee N et al: Fetal and placental pathology in congenital syphilis: a comprehensive study in perinatal autopsy. Fetal Pediatr Pathol. 1-12, 2018
                                                                      5. Rac MW et al: Syphilis during pregnancy: a preventable threat to maternal-fetal health. Am J Obstet Gynecol. 216(4):352-63, 2017
                                                                      6. Vintzileos AM et al: Fetal liver ultrasound measurements during normal pregnancy. Obstet Gynecol. 66(4):477-80, 1985