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Congenital Vallecular Cyst
Bernadette L. Koch, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Epiglottic cyst, base of tongue cyst, ductal cyst, saccular cyst
          • Definitions

            • Congenital cyst arising in vallecula
              • Proposed theories of origin
                • Secondary to obstruction of submucosal glands
                • Secondary to congenital cystic distension of laryngeal saccule

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Ultrasonographic Findings

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      CLINICAL ISSUES

                      • Presentation

                        • Natural History & Prognosis

                          • Treatment

                            DIAGNOSTIC CHECKLIST

                            • Image Interpretation Pearls

                              Selected References

                              1. Cheng J et al: Endoscopic surgical management of inspiratory stridor in newborns and infants. Am J Otolaryngol. 36(5):697-700, 2015
                              2. Lee DH et al: Clinical characteristics and surgical treatment outcomes of vallecular cysts in adults. Acta Otolaryngol. 1-4, 2015
                              3. Hsieh LC et al: The outcomes of infantile vallecular cyst post CO₂ laser treatment. Int J Pediatr Otorhinolaryngol. 77(5):655-7, 2013
                              4. Tsai YT et al: Treatment of vallecular cysts in infants with and without coexisting laryngomalacia using endoscopic laser marsupialization: fifteen-year experience at a single-center. Int J Pediatr Otorhinolaryngol. 77(3):424-8, 2013
                              5. Gonik N et al: Radiofrequency ablation of pediatric vallecular cysts. Int J Pediatr Otorhinolaryngol. 76(12):1819-22, 2012
                              6. Chen EY et al: Transoral approach for direct and complete excision of vallecular cysts in children. Int J Pediatr Otorhinolaryngol. 75(9):1147-51, 2011
                              7. Suzuki J et al: Congenital vallecular cyst in an infant: case report and review of 52 recent cases. J Laryngol Otol. 125(11):1199-203, 2011
                              8. Breysem L et al: Vallecular cyst as a cause of congenital stridor: report of five patients. Pediatr Radiol. 39(8):828-31, 2009
                              9. Cheng SS et al: Symptomatic congenital vallecular cyst in a neonate. J Pediatr. 155(3):446, 2009
                              10. Pereira KD: Laryngeal saccular cyst in an infant. Ear Nose Throat J. 88(1):726-7, 2009
                              11. Sands NB et al: Series of congenital vallecular cysts: a rare yet potentially fatal cause of upper airway obstruction and failure to thrive in the newborn. J Otolaryngol Head Neck Surg. 38(1):6-10, 2009
                              12. Goold AL et al: Lingual hamartoma in an infant: CT and MR imaging. AJNR Am J Neuroradiol. 28(1):30-1, 2007
                              13. Busuttil M et al: Congenital laryngeal cyst: benefits of prenatal diagnosis and multidisciplinary perinatal management. Fetal Diagn Ther. 19(4):373-6, 2004
                              14. Suh MW et al: Apnea spells in an infant with vallecular cyst. Ann Otol Rhinol Laryngol. 113(9):765, 2004
                              15. Yao TC et al: Failure to thrive caused by the coexistence of vallecular cyst, laryngomalacia and gastroesophageal reflux in an infant. Int J Pediatr Otorhinolaryngol. 68(11):1459-64, 2004
                              16. Tibesar RJ et al: Apnea spells in an infant with vallecular cyst. Ann Otol Rhinol Laryngol. 112(9 Pt 1):821-4, 2003
                              17. Cheng KS et al: Vallecular cyst and laryngomalacia in infants: report of six cases and airway management. Anesth Analg. 95(5):1248-50, table of contents, 2002
                              18. Hsieh WS et al: Vallecular cyst: an uncommon cause of stridor in newborn infants. Eur J Pediatr. 159(1-2):79-81, 2000
                              19. Ku AS: Vallecular cyst: report of four cases--one with co-existing laryngomalacia. J Laryngol Otol. 114(3):224-6, 2000
                              20. Gutiérrez JP et al: Vallecular cysts in newborns and young infants. Pediatr Pulmonol. 27(4):282-5, 1999
                              21. Wang CR et al: Vallecular cysts: report of two cases. Pediatr Radiol. 25 Suppl 1:S218-9, 1995
                              22. Gluckman PG et al: Neonatal vallecular cysts and failure to thrive. J Laryngol Otol. 106(5):448-9, 1992
                              23. Myer CM: Vallecular cyst in the newborn. Ear Nose Throat J. 67(2):122-4, 1988
                              24. Albert DM et al: Two cases of vallecular cyst presenting with acute stridor. J Laryngol Otol. 99(4):421-5, 1985
                              25. DeSanto LW: Laryngocele, laryngeal mucocele, large saccules, and laryngeal saccular cysts: a developmental spectrum. Laryngoscope. 84(8):1291-6, 1974
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              KEY FACTS

                              • Terminology

                                • Imaging

                                  • Top Differential Diagnoses

                                    • Clinical Issues

                                      TERMINOLOGY

                                      • Synonyms

                                        • Epiglottic cyst, base of tongue cyst, ductal cyst, saccular cyst
                                      • Definitions

                                        • Congenital cyst arising in vallecula
                                          • Proposed theories of origin
                                            • Secondary to obstruction of submucosal glands
                                            • Secondary to congenital cystic distension of laryngeal saccule

                                      IMAGING

                                      • General Features

                                        • CT Findings

                                          • MR Findings

                                            • Ultrasonographic Findings

                                              DIFFERENTIAL DIAGNOSIS

                                                PATHOLOGY

                                                • General Features

                                                  CLINICAL ISSUES

                                                  • Presentation

                                                    • Natural History & Prognosis

                                                      • Treatment

                                                        DIAGNOSTIC CHECKLIST

                                                        • Image Interpretation Pearls

                                                          Selected References

                                                          1. Cheng J et al: Endoscopic surgical management of inspiratory stridor in newborns and infants. Am J Otolaryngol. 36(5):697-700, 2015
                                                          2. Lee DH et al: Clinical characteristics and surgical treatment outcomes of vallecular cysts in adults. Acta Otolaryngol. 1-4, 2015
                                                          3. Hsieh LC et al: The outcomes of infantile vallecular cyst post CO₂ laser treatment. Int J Pediatr Otorhinolaryngol. 77(5):655-7, 2013
                                                          4. Tsai YT et al: Treatment of vallecular cysts in infants with and without coexisting laryngomalacia using endoscopic laser marsupialization: fifteen-year experience at a single-center. Int J Pediatr Otorhinolaryngol. 77(3):424-8, 2013
                                                          5. Gonik N et al: Radiofrequency ablation of pediatric vallecular cysts. Int J Pediatr Otorhinolaryngol. 76(12):1819-22, 2012
                                                          6. Chen EY et al: Transoral approach for direct and complete excision of vallecular cysts in children. Int J Pediatr Otorhinolaryngol. 75(9):1147-51, 2011
                                                          7. Suzuki J et al: Congenital vallecular cyst in an infant: case report and review of 52 recent cases. J Laryngol Otol. 125(11):1199-203, 2011
                                                          8. Breysem L et al: Vallecular cyst as a cause of congenital stridor: report of five patients. Pediatr Radiol. 39(8):828-31, 2009
                                                          9. Cheng SS et al: Symptomatic congenital vallecular cyst in a neonate. J Pediatr. 155(3):446, 2009
                                                          10. Pereira KD: Laryngeal saccular cyst in an infant. Ear Nose Throat J. 88(1):726-7, 2009
                                                          11. Sands NB et al: Series of congenital vallecular cysts: a rare yet potentially fatal cause of upper airway obstruction and failure to thrive in the newborn. J Otolaryngol Head Neck Surg. 38(1):6-10, 2009
                                                          12. Goold AL et al: Lingual hamartoma in an infant: CT and MR imaging. AJNR Am J Neuroradiol. 28(1):30-1, 2007
                                                          13. Busuttil M et al: Congenital laryngeal cyst: benefits of prenatal diagnosis and multidisciplinary perinatal management. Fetal Diagn Ther. 19(4):373-6, 2004
                                                          14. Suh MW et al: Apnea spells in an infant with vallecular cyst. Ann Otol Rhinol Laryngol. 113(9):765, 2004
                                                          15. Yao TC et al: Failure to thrive caused by the coexistence of vallecular cyst, laryngomalacia and gastroesophageal reflux in an infant. Int J Pediatr Otorhinolaryngol. 68(11):1459-64, 2004
                                                          16. Tibesar RJ et al: Apnea spells in an infant with vallecular cyst. Ann Otol Rhinol Laryngol. 112(9 Pt 1):821-4, 2003
                                                          17. Cheng KS et al: Vallecular cyst and laryngomalacia in infants: report of six cases and airway management. Anesth Analg. 95(5):1248-50, table of contents, 2002
                                                          18. Hsieh WS et al: Vallecular cyst: an uncommon cause of stridor in newborn infants. Eur J Pediatr. 159(1-2):79-81, 2000
                                                          19. Ku AS: Vallecular cyst: report of four cases--one with co-existing laryngomalacia. J Laryngol Otol. 114(3):224-6, 2000
                                                          20. Gutiérrez JP et al: Vallecular cysts in newborns and young infants. Pediatr Pulmonol. 27(4):282-5, 1999
                                                          21. Wang CR et al: Vallecular cysts: report of two cases. Pediatr Radiol. 25 Suppl 1:S218-9, 1995
                                                          22. Gluckman PG et al: Neonatal vallecular cysts and failure to thrive. J Laryngol Otol. 106(5):448-9, 1992
                                                          23. Myer CM: Vallecular cyst in the newborn. Ear Nose Throat J. 67(2):122-4, 1988
                                                          24. Albert DM et al: Two cases of vallecular cyst presenting with acute stridor. J Laryngol Otol. 99(4):421-5, 1985
                                                          25. DeSanto LW: Laryngocele, laryngeal mucocele, large saccules, and laryngeal saccular cysts: a developmental spectrum. Laryngoscope. 84(8):1291-6, 1974