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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Constrictive bronchiolitis (CB)
- Bronchiolitis obliterans syndrome (BOS)
Synonyms
- Bronchiolitis obliterans
- Obliterative bronchiolitis
Definitions
- Specific pattern of pulmonary response to diverse injuries; may be idiopathic
- Submucosal and peribronchiolar fibrosis with bronchiolar narrowing or luminal obliteration
- Concentric fibrosis of bronchiolar wall
- Between bronchiolar epithelium and muscularis mucosa
- Bronchiolar narrowing &/or obliteration
- Absence of intraluminal granulation tissue polyps
- No surrounding parenchymal inflammation
- Concentric fibrosis of bronchiolar wall
- Submucosal and peribronchiolar fibrosis with bronchiolar narrowing or luminal obliteration
- Specific pattern of pulmonary response to diverse injuries; may be idiopathic
IMAGING
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Histologic Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Clinically Relevant Pathologic Features
Pathologic Interpretation Pearls
Selected References
- Kligerman SJ et al: Mosaic attenuation: etiology, methods of differentiation, and pitfalls. Radiographics. 35(5):1360-80, 2015
- Abbott GF et al: Imaging of small airways disease. J Thorac Imaging. 24(4):285-98, 2009
- Chen CZ et al: Small airways obstruction syndrome in clinical practice. Respirology. 14(3):393-8, 2009
- Pipavath SJ, Lynch DA, Cool C, Brown KK, Newell JD. Radiologic and pathologic features of bronchiolitis. AJR Am J Roentgenol. 2005 Aug;185(2):354-63.
- Couture C et al: Histopathology of bronchiolar disorders. Semin Respir Crit Care Med. 24(5):489-98, 2003
- Ryu JH et al: Bronchiolar disorders. Am J Respir Crit Care Med. 168(11):1277-92, 2003
- Colby TV: Bronchiolitis, pathologic considerations. M J Clin Pathol 1998;109:101-109.
- Müller NL et al: Diseases of the bronchioles: CT and histopathologic findings. Radiology. 196(1):3-12, 1995
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Constrictive bronchiolitis (CB)
- Bronchiolitis obliterans syndrome (BOS)
Synonyms
- Bronchiolitis obliterans
- Obliterative bronchiolitis
Definitions
- Specific pattern of pulmonary response to diverse injuries; may be idiopathic
- Submucosal and peribronchiolar fibrosis with bronchiolar narrowing or luminal obliteration
- Concentric fibrosis of bronchiolar wall
- Between bronchiolar epithelium and muscularis mucosa
- Bronchiolar narrowing &/or obliteration
- Absence of intraluminal granulation tissue polyps
- No surrounding parenchymal inflammation
- Concentric fibrosis of bronchiolar wall
- Submucosal and peribronchiolar fibrosis with bronchiolar narrowing or luminal obliteration
- Specific pattern of pulmonary response to diverse injuries; may be idiopathic
IMAGING
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Histologic Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Clinically Relevant Pathologic Features
Pathologic Interpretation Pearls
Selected References
- Kligerman SJ et al: Mosaic attenuation: etiology, methods of differentiation, and pitfalls. Radiographics. 35(5):1360-80, 2015
- Abbott GF et al: Imaging of small airways disease. J Thorac Imaging. 24(4):285-98, 2009
- Chen CZ et al: Small airways obstruction syndrome in clinical practice. Respirology. 14(3):393-8, 2009
- Pipavath SJ, Lynch DA, Cool C, Brown KK, Newell JD. Radiologic and pathologic features of bronchiolitis. AJR Am J Roentgenol. 2005 Aug;185(2):354-63.
- Couture C et al: Histopathology of bronchiolar disorders. Semin Respir Crit Care Med. 24(5):489-98, 2003
- Ryu JH et al: Bronchiolar disorders. Am J Respir Crit Care Med. 168(11):1277-92, 2003
- Colby TV: Bronchiolitis, pathologic considerations. M J Clin Pathol 1998;109:101-109.
- Müller NL et al: Diseases of the bronchioles: CT and histopathologic findings. Radiology. 196(1):3-12, 1995
