Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Coronavirus disease 2019 (COVID-19)
Angiotensin converting enzyme 2 receptor (ACE2)
Definitions
COVID-19 = disease caused by SARS-CoV-2 virus
Is zoonosis (disease transmitted to humans from animals)
IMAGING
General Features
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Gross Pathologic & Surgical Features
Etiology
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Reporting Tips
Selected References
Asadi-Pooya AA et al: Central nervous system manifestations of COVID-19: a systematic review. J Neurol Sci. 413:116832, 2020
Baig AM: Neurological manifestations in COVID-19 caused by SARS-CoV-2. CNS Neurosci Ther. 26(5):499-501, 2020
Baig AM: Updates on what ACS reported: emerging evidences of COVID-19 with nervous system involvement. ACS Chem Neurosci. 11(9):1204-5, 2020
Bowles L et al: Lupus anticoagulant and abnormal coagulation tests in patients with Covid-19. N Engl J Med.383(3):288-90, 2020
Chen B et al: Insights into neuroimaging findings of patients with Coronavirus disease 2019 presenting with neurological manifestations. Front Neurol. 11:593520, 2020
Chen H et al: Clinical and imaging features of COVID-19. Radiol Infect Dis. 7(2):43-50, 2020
Harahsheh AS et al: Missed or delayed diagnosis of kawasaki disease during the 2019 novel coronavirus disease (COVID-19) pandemic. J Pediatr. 222:261-2, 2020
Kandemirli SG et al: Brain MRI findings in patients in the intensive care unit with COVID-19 infection. Radiology. 201697, 2020
Lersy F et al: Critical illness-associated cerebral microbleeds for patients with severe COVID-19: etiologic hypotheses. J Neurol. 21;1-9, 2020
Mahajan A et al: Novel Coronavirus: what neuroradiologists as citizens of the world need to know. AJNR Am J Neuroradiol. 41(4):552-4, 2020
Mankad K et al: COVID-19: a primer for Neuroradiologists. Neuroradiology. 62(6):647-8, 2020
Moonis G et al: The spectrum of neuroimaging findings on CT and MRI in adults with Coronavirus disease (COVID-19). AJR Am J Roentgenol. ePub, 2020
Moriguchi T et al: A first case of meningitis/encephalitis associated with SARS-Coronavirus-2. Int J Infect Dis. 94:55-8, 2020
Morris M et al: Neuroradiologists, be mindful of the neuroinvasive potential of COVID-19. AJNR Am J Neuroradiol. 41(6):E37-9, 2020
Natoli S et al: Does SARS-Cov-2 invade the brain? Translational lessons from animal models. Eur J Neurol. 27(9):1764-73, 2020
Oxley TJ et al: Large-vessel stroke as a presenting feature of Covid-19 in the young. N Engl J Med.14;382(20), 2020
Paybast S et al: Novel Coronavirus disease (COVID-19) and central nervous system complications: what neurologist need to know. Acta Neurol Taiwan. 29(1):24-31, 2020
Phillips CD et al: From the eye of the storm: multi-institutional practical perspectives on neuroradiology from the COVID-19 outbreak in New York city. AJNR Am J Neuroradiol. 41(6):960-5, 2020
Zanin L et al: SARS-CoV-2 can induce brain and spine demyelinating lesions. Acta Neurochir (Wien). 162(7):1491-4, 2020
Kuo KH et al: Cerebral microbleeds associated with critical illness. Acta Neurol Taiwan. 28(1):25-26, 2019
Fanou EM et al: Critical illness-associated cerebral microbleeds. Stroke. 48(4):1085-7, 2017
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Pathology
TERMINOLOGY
Abbreviations
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Coronavirus disease 2019 (COVID-19)
Angiotensin converting enzyme 2 receptor (ACE2)
Definitions
COVID-19 = disease caused by SARS-CoV-2 virus
Is zoonosis (disease transmitted to humans from animals)
IMAGING
General Features
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Gross Pathologic & Surgical Features
Etiology
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Reporting Tips
Selected References
Asadi-Pooya AA et al: Central nervous system manifestations of COVID-19: a systematic review. J Neurol Sci. 413:116832, 2020
Baig AM: Neurological manifestations in COVID-19 caused by SARS-CoV-2. CNS Neurosci Ther. 26(5):499-501, 2020
Baig AM: Updates on what ACS reported: emerging evidences of COVID-19 with nervous system involvement. ACS Chem Neurosci. 11(9):1204-5, 2020
Bowles L et al: Lupus anticoagulant and abnormal coagulation tests in patients with Covid-19. N Engl J Med.383(3):288-90, 2020
Chen B et al: Insights into neuroimaging findings of patients with Coronavirus disease 2019 presenting with neurological manifestations. Front Neurol. 11:593520, 2020
Chen H et al: Clinical and imaging features of COVID-19. Radiol Infect Dis. 7(2):43-50, 2020
Harahsheh AS et al: Missed or delayed diagnosis of kawasaki disease during the 2019 novel coronavirus disease (COVID-19) pandemic. J Pediatr. 222:261-2, 2020
Kandemirli SG et al: Brain MRI findings in patients in the intensive care unit with COVID-19 infection. Radiology. 201697, 2020
Lersy F et al: Critical illness-associated cerebral microbleeds for patients with severe COVID-19: etiologic hypotheses. J Neurol. 21;1-9, 2020
Mahajan A et al: Novel Coronavirus: what neuroradiologists as citizens of the world need to know. AJNR Am J Neuroradiol. 41(4):552-4, 2020
Mankad K et al: COVID-19: a primer for Neuroradiologists. Neuroradiology. 62(6):647-8, 2020
Moonis G et al: The spectrum of neuroimaging findings on CT and MRI in adults with Coronavirus disease (COVID-19). AJR Am J Roentgenol. ePub, 2020
Moriguchi T et al: A first case of meningitis/encephalitis associated with SARS-Coronavirus-2. Int J Infect Dis. 94:55-8, 2020
Morris M et al: Neuroradiologists, be mindful of the neuroinvasive potential of COVID-19. AJNR Am J Neuroradiol. 41(6):E37-9, 2020
Natoli S et al: Does SARS-Cov-2 invade the brain? Translational lessons from animal models. Eur J Neurol. 27(9):1764-73, 2020
Oxley TJ et al: Large-vessel stroke as a presenting feature of Covid-19 in the young. N Engl J Med.14;382(20), 2020
Paybast S et al: Novel Coronavirus disease (COVID-19) and central nervous system complications: what neurologist need to know. Acta Neurol Taiwan. 29(1):24-31, 2020
Phillips CD et al: From the eye of the storm: multi-institutional practical perspectives on neuroradiology from the COVID-19 outbreak in New York city. AJNR Am J Neuroradiol. 41(6):960-5, 2020
Zanin L et al: SARS-CoV-2 can induce brain and spine demyelinating lesions. Acta Neurochir (Wien). 162(7):1491-4, 2020
Kuo KH et al: Cerebral microbleeds associated with critical illness. Acta Neurol Taiwan. 28(1):25-26, 2019
Fanou EM et al: Critical illness-associated cerebral microbleeds. Stroke. 48(4):1085-7, 2017
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