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CPA-IAC Facial Nerve Schwannoma
Bronwyn E. Hamilton, MD; H. Ric Harnsberger, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Facial nerve schwannoma (FNS)
            • Synonyms

              • Facial neuroma, facial neurilemmoma
            • Definitions

              • FNS: Rare, benign tumor of Schwann cells that surround facial nerve in cerebellopontine angle (CPA)-internal auditory canal (IAC)

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Bartindale M et al: Facial schwannoma management outcomes: a systematic review of the literature. Otolaryngol Head Neck Surg. 163(2):293-301, 2020
                                        2. Furukawa T et al: Facial nerve and chorda tympani schwannomas: case series, and advantages of using non-rigid registration of post-enhanced 3D-T1 Turbo Field Echo and CT images (TURFECT) in their diagnosis and surgical treatment. Auris Nasus Larynx. 47(3):383-90, 2020
                                        3. Gao W et al: Facial nerve meningioma: a case mimicking facial nerve schwannoma. Ear Nose Throat J. 145561320962582, 2020
                                        4. Lahlou G et al: Evolution of the management of sporadic facial nerve schwannomas: a series of 83 cases over three decades. Clin Otolaryngol. 45(4):595-9, 2020
                                        5. Loos E et al: Intratemporal facial nerve schwannomas: multicenter experience of 80 cases. Eur Arch Otorhinolaryngol. 277(8):2209-17, 2020
                                        6. Mehta GU et al: Effect of anatomic segment involvement on stereotactic radiosurgery for facial nerve schwannomas: an international multicenter cohort study. Neurosurgery. 88(1):E91-8, 2020
                                        7. Rotter J et al: Surgery versus radiosurgery for facial nerve schwannoma: a systematic review and meta-analysis of facial nerve function, postoperative complications, and progression. J Neurosurg. 1-12, 2020
                                        8. Goel A et al: Subtemporal "interdural" surgical approach for "giant" facial nerve neurinomas. World Neurosurg. 110:e835-41, 2018
                                        9. Sah SK et al: Facial nerve schwannomas: a case series with an analysis of imaging findings. Neurol India. 66(1):139-43, 2018
                                        10. Li Y et al: A retrospective study on facial nerve schwannomas: a disease with a high risk of misdiagnosis and hearing loss. Eur Arch Otorhinolaryngol. 274(9):3359-66, 2017
                                        11. Carlson ML et al: Facial nerve schwannomas: review of 80 cases over 25 years at Mayo Clinic. Mayo Clin Proc. 91(11):1563-76, 2016
                                        12. Mundada P et al: Imaging of facial nerve schwannomas: diagnostic pearls and potential pitfalls. Diagn Interv Radiol. 22(1):40-6, 2016
                                        13. Moon JH et al: Gamma Knife surgery for facial nerve schwannomas. J Neurosurg. 121 Suppl:116-22, 2014
                                        14. McRackan TR et al: Facial nerve outcomes in facial nerve schwannomas. Otol Neurotol. 2012 Jan;33(1):78-82. Erratum in: Otol Neurotol. 33(3):472, 2012
                                        15. Mowry S et al: Surgical management of internal auditory canal and cerebellopontine angle facial nerve schwannoma. Otol Neurotol. 33(6):1071-6, 2012
                                        16. Chao WC et al: Facial nerve schwannoma. Otolaryngol Head Neck Surg. 141(1):146-7, 2009
                                        17. Madhok R et al: Gamma knife radiosurgery for facial schwannomas. Neurosurgery. 64(6):1102-5; discussion 1105, 2009
                                        18. Presutti L et al: Facial nerve schwannoma. Otol Neurotol. 30(5):683-5, 2009
                                        19. Thompson AL et al: Magnetic resonance imaging of facial nerve schwannoma. Laryngoscope. 119(12):2428-36, 2009
                                        20. Litré CF et al: Gamma knife surgery for facial nerve schwannomas. Prog Neurol Surg. 21:131-5, 2008
                                        21. McMonagle B et al: Facial schwannoma: results of a large case series and review. J Laryngol Otol. 122(11):1139-50, 2008
                                        22. Prasai A et al: A facial nerve schwannoma masquerading as a vestibular schwannoma. Ear Nose Throat J. 87(9):E4-6, 2008
                                        23. Lee JD et al: Management of facial nerve schwannoma in patients with favorable facial function. Laryngoscope. 117(6):1063-8, 2007
                                        24. Park HY et al: Intracanalicular facial nerve schwannoma. Otol Neurotol. 28(3):376-80, 2007
                                        25. Wiggins RH 3rd et al: The many faces of facial nerve schwannoma. AJNR Am J Neuroradiol. 27(3):694-9, 2006
                                        26. Kim JC et al: Facial nerve schwannoma. Ann Otol Rhinol Laryngol. 112(2):185-7, 2003
                                        27. Liu R et al: Facial nerve schwannoma: surgical excision versus conservative management. Ann Otol Rhinol Laryngol. 110(11):1025-9, 2001
                                        28. Salzman KL et al: Dumbbell schwannomas of the internal auditory canal. AJNR Am J Neuroradiol. 22(7):1368-76, 2001
                                        29. Yokota N et al: Facial nerve schwannoma in the cerebellopontine cistern. Findings on high resolution CT and MR cisternography. Br J Neurosurg. 13(5):512-5, 1999
                                        30. McMenomey SO et al: Facial nerve neuromas presenting as acoustic tumors. Am J Otol. 15(3):307-12, 1994
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Facial nerve schwannoma (FNS)
                                                  • Synonyms

                                                    • Facial neuroma, facial neurilemmoma
                                                  • Definitions

                                                    • FNS: Rare, benign tumor of Schwann cells that surround facial nerve in cerebellopontine angle (CPA)-internal auditory canal (IAC)

                                                  IMAGING

                                                  • General Features

                                                    • CT Findings

                                                      • MR Findings

                                                        • Imaging Recommendations

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          DIAGNOSTIC CHECKLIST

                                                                          • Consider

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Bartindale M et al: Facial schwannoma management outcomes: a systematic review of the literature. Otolaryngol Head Neck Surg. 163(2):293-301, 2020
                                                                              2. Furukawa T et al: Facial nerve and chorda tympani schwannomas: case series, and advantages of using non-rigid registration of post-enhanced 3D-T1 Turbo Field Echo and CT images (TURFECT) in their diagnosis and surgical treatment. Auris Nasus Larynx. 47(3):383-90, 2020
                                                                              3. Gao W et al: Facial nerve meningioma: a case mimicking facial nerve schwannoma. Ear Nose Throat J. 145561320962582, 2020
                                                                              4. Lahlou G et al: Evolution of the management of sporadic facial nerve schwannomas: a series of 83 cases over three decades. Clin Otolaryngol. 45(4):595-9, 2020
                                                                              5. Loos E et al: Intratemporal facial nerve schwannomas: multicenter experience of 80 cases. Eur Arch Otorhinolaryngol. 277(8):2209-17, 2020
                                                                              6. Mehta GU et al: Effect of anatomic segment involvement on stereotactic radiosurgery for facial nerve schwannomas: an international multicenter cohort study. Neurosurgery. 88(1):E91-8, 2020
                                                                              7. Rotter J et al: Surgery versus radiosurgery for facial nerve schwannoma: a systematic review and meta-analysis of facial nerve function, postoperative complications, and progression. J Neurosurg. 1-12, 2020
                                                                              8. Goel A et al: Subtemporal "interdural" surgical approach for "giant" facial nerve neurinomas. World Neurosurg. 110:e835-41, 2018
                                                                              9. Sah SK et al: Facial nerve schwannomas: a case series with an analysis of imaging findings. Neurol India. 66(1):139-43, 2018
                                                                              10. Li Y et al: A retrospective study on facial nerve schwannomas: a disease with a high risk of misdiagnosis and hearing loss. Eur Arch Otorhinolaryngol. 274(9):3359-66, 2017
                                                                              11. Carlson ML et al: Facial nerve schwannomas: review of 80 cases over 25 years at Mayo Clinic. Mayo Clin Proc. 91(11):1563-76, 2016
                                                                              12. Mundada P et al: Imaging of facial nerve schwannomas: diagnostic pearls and potential pitfalls. Diagn Interv Radiol. 22(1):40-6, 2016
                                                                              13. Moon JH et al: Gamma Knife surgery for facial nerve schwannomas. J Neurosurg. 121 Suppl:116-22, 2014
                                                                              14. McRackan TR et al: Facial nerve outcomes in facial nerve schwannomas. Otol Neurotol. 2012 Jan;33(1):78-82. Erratum in: Otol Neurotol. 33(3):472, 2012
                                                                              15. Mowry S et al: Surgical management of internal auditory canal and cerebellopontine angle facial nerve schwannoma. Otol Neurotol. 33(6):1071-6, 2012
                                                                              16. Chao WC et al: Facial nerve schwannoma. Otolaryngol Head Neck Surg. 141(1):146-7, 2009
                                                                              17. Madhok R et al: Gamma knife radiosurgery for facial schwannomas. Neurosurgery. 64(6):1102-5; discussion 1105, 2009
                                                                              18. Presutti L et al: Facial nerve schwannoma. Otol Neurotol. 30(5):683-5, 2009
                                                                              19. Thompson AL et al: Magnetic resonance imaging of facial nerve schwannoma. Laryngoscope. 119(12):2428-36, 2009
                                                                              20. Litré CF et al: Gamma knife surgery for facial nerve schwannomas. Prog Neurol Surg. 21:131-5, 2008
                                                                              21. McMonagle B et al: Facial schwannoma: results of a large case series and review. J Laryngol Otol. 122(11):1139-50, 2008
                                                                              22. Prasai A et al: A facial nerve schwannoma masquerading as a vestibular schwannoma. Ear Nose Throat J. 87(9):E4-6, 2008
                                                                              23. Lee JD et al: Management of facial nerve schwannoma in patients with favorable facial function. Laryngoscope. 117(6):1063-8, 2007
                                                                              24. Park HY et al: Intracanalicular facial nerve schwannoma. Otol Neurotol. 28(3):376-80, 2007
                                                                              25. Wiggins RH 3rd et al: The many faces of facial nerve schwannoma. AJNR Am J Neuroradiol. 27(3):694-9, 2006
                                                                              26. Kim JC et al: Facial nerve schwannoma. Ann Otol Rhinol Laryngol. 112(2):185-7, 2003
                                                                              27. Liu R et al: Facial nerve schwannoma: surgical excision versus conservative management. Ann Otol Rhinol Laryngol. 110(11):1025-9, 2001
                                                                              28. Salzman KL et al: Dumbbell schwannomas of the internal auditory canal. AJNR Am J Neuroradiol. 22(7):1368-76, 2001
                                                                              29. Yokota N et al: Facial nerve schwannoma in the cerebellopontine cistern. Findings on high resolution CT and MR cisternography. Br J Neurosurg. 13(5):512-5, 1999
                                                                              30. McMenomey SO et al: Facial nerve neuromas presenting as acoustic tumors. Am J Otol. 15(3):307-12, 1994