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CPA-IAC Meningitis
H. Ric Harnsberger, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Leptomeningitis, infectious meningitis
            • Definitions

              • Acute or chronic infectious infiltrate of pia, arachnoid, & CSF in vicinity of T-bone, internal auditory canal (IAC), & cerebellopontine angle (CPA)
              • Classified as acute pyogenic (bacterial), lymphocytic (viral), or chronic (tuberculous or granulomatous)

            IMAGING

            • General Features

              • Imaging Recommendations

                • CT Findings

                  • MR Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      Selected References

                                      1. Oliveira CR et al: Brain magnetic resonance imaging of infants with bacterial meningitis. J Pediatr. 165(1):134-9, 2014
                                      2. Mohan S et al: Imaging of meningitis and ventriculitis. Neuroimaging Clin N Am. 22(4):557-83, 2012
                                      3. Lee MH et al: Prevalence and appearance of the posterior wall defects of the temporal bone caused by presumed arachnoid granulations and their clinical significance: CT findings. AJNR Am J Neuroradiol. 29(9):1704-7, 2008
                                      4. Tebruegge M et al: Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis. Clin Microbiol Rev. 21(3):519-37, 2008
                                      5. Smirniotopoulos JG et al: Patterns of contrast enhancement in the brain and meninges. Radiographics. 27(2):525-51, 2007
                                      6. Brown NE et al: Diagnosis and management of spontaneous cerebrospinal fluid-middle ear effusion and otorrhea. Laryngoscope. 114(5):800-5, 2004
                                      7. Migirov L: Computed tomographic versus surgical findings in complicated acute otomastoiditis. Ann Otol Rhinol Laryngol. 112(8):675-7, 2003
                                      8. Stone JA et al: Evaluation of CSF leaks: high-resolution CT compared with contrast-enhanced CT and radionuclide cisternography. AJNR Am J Neuroradiol. 20(4):706-12, 1999
                                      9. Quiney RE et al: Recurrent meningitis in children due to inner ear abnormalities. J Laryngol Otol. 103(5):473-80, 1989
                                      10. Vermeersch H et al: The temporal bone as route of infection in recurrent meningitis. J Otolaryngol. 9(3):199-201, 1980
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Pathology

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Synonyms

                                                  • Leptomeningitis, infectious meningitis
                                                • Definitions

                                                  • Acute or chronic infectious infiltrate of pia, arachnoid, & CSF in vicinity of T-bone, internal auditory canal (IAC), & cerebellopontine angle (CPA)
                                                  • Classified as acute pyogenic (bacterial), lymphocytic (viral), or chronic (tuberculous or granulomatous)

                                                IMAGING

                                                • General Features

                                                  • Imaging Recommendations

                                                    • CT Findings

                                                      • MR Findings

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Gross Pathologic & Surgical Features

                                                              • Microscopic Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Consider

                                                                          Selected References

                                                                          1. Oliveira CR et al: Brain magnetic resonance imaging of infants with bacterial meningitis. J Pediatr. 165(1):134-9, 2014
                                                                          2. Mohan S et al: Imaging of meningitis and ventriculitis. Neuroimaging Clin N Am. 22(4):557-83, 2012
                                                                          3. Lee MH et al: Prevalence and appearance of the posterior wall defects of the temporal bone caused by presumed arachnoid granulations and their clinical significance: CT findings. AJNR Am J Neuroradiol. 29(9):1704-7, 2008
                                                                          4. Tebruegge M et al: Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis. Clin Microbiol Rev. 21(3):519-37, 2008
                                                                          5. Smirniotopoulos JG et al: Patterns of contrast enhancement in the brain and meninges. Radiographics. 27(2):525-51, 2007
                                                                          6. Brown NE et al: Diagnosis and management of spontaneous cerebrospinal fluid-middle ear effusion and otorrhea. Laryngoscope. 114(5):800-5, 2004
                                                                          7. Migirov L: Computed tomographic versus surgical findings in complicated acute otomastoiditis. Ann Otol Rhinol Laryngol. 112(8):675-7, 2003
                                                                          8. Stone JA et al: Evaluation of CSF leaks: high-resolution CT compared with contrast-enhanced CT and radionuclide cisternography. AJNR Am J Neuroradiol. 20(4):706-12, 1999
                                                                          9. Quiney RE et al: Recurrent meningitis in children due to inner ear abnormalities. J Laryngol Otol. 103(5):473-80, 1989
                                                                          10. Vermeersch H et al: The temporal bone as route of infection in recurrent meningitis. J Otolaryngol. 9(3):199-201, 1980