Histologically benign epithelial tumor arising from squamous rests along involuted hypophyseal-Rathke duct
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Chen X et al: Noninvasive molecular diagnosis of craniopharyngioma with MRI-based radiomics approach. BMC Neurol. 19(1):6, 2019
Omay SB et al: Do craniopharyngioma molecular signatures correlate with clinical characteristics? J Neurosurg. 128(5):1473-8, 2018
Yue Q et al: Prediction of BRAF mutation status of craniopharyngioma using magnetic resonance imaging features. J Neurosurg. 129(1):27-34, 2018
Larkin S et al: Recent advances in molecular pathology of craniopharyngioma. F1000Res. 6:1202, 2017
Roque A et al: BRAF-V600E mutant papillary craniopharyngioma dramatically responds to combination BRAF and MEK inhibitors. CNS Oncol. 6(2):95-9, 2017
Müller HL: Preoperative staging in childhood craniopharyngioma: standardization as a first step towards improved outcome. Endocrine. 51(1):1-3, 2016
Martinez-Barbera JP: Molecular and cellular pathogenesis of adamantinomatous craniopharyngioma. Neuropathol Appl Neurobiol. 41(6):721-32, 2015
Steinbok P: Craniopharyngioma in children: long-term outcomes. Neurol Med Chir (Tokyo). 55(9):722-6, 2015
Sterkenburg AS et al: Survival, hypothalamic obesity, and neuropsychological/psychosocial status after childhood-onset craniopharyngioma: newly reported long-term outcomes. Neuro Oncol. 17(7):1029-38, 2015
Hussain I et al: Molecular oncogenesis of craniopharyngioma: current and future strategies for the development of targeted therapies. J Neurosurg. 119(1):106-12, 2013
Plaza MJ et al: Conventional and advanced MRI features of pediatric intracranial tumors: posterior fossa and suprasellar tumors. AJR Am J Roentgenol. 200(5):1115-24, 2013
Watanabe K et al: Delineation of optic nerves and chiasm in close proximity to large suprasellar tumors with contrast-enhanced FIESTA MR imaging. Radiology. 264(3):852-8, 2012
Famini P et al: Pituitary magnetic resonance imaging for sellar and parasellar masses: ten-year experience in 2598 patients. J Clin Endocrinol Metab. 96(6):1633-41, 2011
Yamada S et al: Surgical outcome in 90 patients with craniopharyngioma: an evaluation of transsphenoidal surgery. World Neurosurg. 74(2-3):320-30, 2010
Choi SH et al: Pituitary adenoma, craniopharyngioma, and Rathke cleft cyst involving both intrasellar and suprasellar regions: differentiation using MRI. Clin Radiol. 62(5):453-62, 2007
Curran JG et al: Imaging of craniopharyngioma. Childs Nerv Syst. 21(8-9):635-9, 2005
Tavangar SM et al: Craniopharyngioma: a clinicopathological study of 141 cases. Endocr Pathol. 15(4):339-44, 2004
Sartoretti-Schefer S et al: MR differentiation of adamantinous and squamous-papillary craniopharyngiomas. AJNR Am J Neuroradiol. 18(1):77-87, 1997
Tsuda M et al: CT and MR imaging of craniopharyngioma. Eur Radiol. 7(4):464-9, 1997
Eldevik OP et al: Craniopharyngioma: radiologic and histologic findings and recurrence. AJNR Am J Neuroradiol. 17(8):1427-39, 1996
Histologically benign epithelial tumor arising from squamous rests along involuted hypophyseal-Rathke duct
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Chen X et al: Noninvasive molecular diagnosis of craniopharyngioma with MRI-based radiomics approach. BMC Neurol. 19(1):6, 2019
Omay SB et al: Do craniopharyngioma molecular signatures correlate with clinical characteristics? J Neurosurg. 128(5):1473-8, 2018
Yue Q et al: Prediction of BRAF mutation status of craniopharyngioma using magnetic resonance imaging features. J Neurosurg. 129(1):27-34, 2018
Larkin S et al: Recent advances in molecular pathology of craniopharyngioma. F1000Res. 6:1202, 2017
Roque A et al: BRAF-V600E mutant papillary craniopharyngioma dramatically responds to combination BRAF and MEK inhibitors. CNS Oncol. 6(2):95-9, 2017
Müller HL: Preoperative staging in childhood craniopharyngioma: standardization as a first step towards improved outcome. Endocrine. 51(1):1-3, 2016
Martinez-Barbera JP: Molecular and cellular pathogenesis of adamantinomatous craniopharyngioma. Neuropathol Appl Neurobiol. 41(6):721-32, 2015
Steinbok P: Craniopharyngioma in children: long-term outcomes. Neurol Med Chir (Tokyo). 55(9):722-6, 2015
Sterkenburg AS et al: Survival, hypothalamic obesity, and neuropsychological/psychosocial status after childhood-onset craniopharyngioma: newly reported long-term outcomes. Neuro Oncol. 17(7):1029-38, 2015
Hussain I et al: Molecular oncogenesis of craniopharyngioma: current and future strategies for the development of targeted therapies. J Neurosurg. 119(1):106-12, 2013
Plaza MJ et al: Conventional and advanced MRI features of pediatric intracranial tumors: posterior fossa and suprasellar tumors. AJR Am J Roentgenol. 200(5):1115-24, 2013
Watanabe K et al: Delineation of optic nerves and chiasm in close proximity to large suprasellar tumors with contrast-enhanced FIESTA MR imaging. Radiology. 264(3):852-8, 2012
Famini P et al: Pituitary magnetic resonance imaging for sellar and parasellar masses: ten-year experience in 2598 patients. J Clin Endocrinol Metab. 96(6):1633-41, 2011
Yamada S et al: Surgical outcome in 90 patients with craniopharyngioma: an evaluation of transsphenoidal surgery. World Neurosurg. 74(2-3):320-30, 2010
Choi SH et al: Pituitary adenoma, craniopharyngioma, and Rathke cleft cyst involving both intrasellar and suprasellar regions: differentiation using MRI. Clin Radiol. 62(5):453-62, 2007
Curran JG et al: Imaging of craniopharyngioma. Childs Nerv Syst. 21(8-9):635-9, 2005
Tavangar SM et al: Craniopharyngioma: a clinicopathological study of 141 cases. Endocr Pathol. 15(4):339-44, 2004
Sartoretti-Schefer S et al: MR differentiation of adamantinous and squamous-papillary craniopharyngiomas. AJNR Am J Neuroradiol. 18(1):77-87, 1997
Tsuda M et al: CT and MR imaging of craniopharyngioma. Eur Radiol. 7(4):464-9, 1997
Eldevik OP et al: Craniopharyngioma: radiologic and histologic findings and recurrence. AJNR Am J Neuroradiol. 17(8):1427-39, 1996
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