Disease of unknown etiology characterized by transmural inflammation of GI tract
IMAGING
General Features
Fluoroscopic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Other Modality Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Guglielmo FF et al: Small bowel crohn disease at CT and MR enterography: imaging atlas and glossary of terms. Radiographics. 40(2):354-75, 2020
Bruining DH et al: Consensus recommendations for evaluation, interpretation, and utilization of computed tomography and magnetic resonance enterography in patients with small bowel Crohn's disease. Radiology. 286(3):776-99, 2018
Gajendran M et al: A comprehensive review and update on Crohn's disease. Dis Mon. 64(2):20-57, 2018
Gomollón F et al: 3rd European evidence-based consensus on the diagnosis and management of crohn's disease 2016: part 1: diagnosis and medical management. J Crohns Colitis. 11(1):3-25, 2017
Allen BC et al: MR enterography for assessment and management of small bowel Crohn disease. Radiol Clin North Am. 52(4):799-810, 2014
Mandel MD et al: Have biologics changed the natural history of Crohn's disease? Dig Dis. 32(4):351-9, 2014
Marineaţă A et al: Extra intestinal manifestations and complications in inflammatory bowel disease. Rev Med Chir Soc Med Nat Iasi. 118(2):279-88, 2014
Qiu Y et al: Systematic review with meta-analysis: magnetic resonance enterography vs. computed tomography enterography for evaluating disease activity in small bowel Crohn's disease. Aliment Pharmacol Ther. 40(2):134-46, 2014
Rodriguez P et al: Imaging Crohn disease: MR enterography. J Comput Assist Tomogr. 38(2):219-27, 2014
Yassin NA et al: Systematic review: the combined surgical and medical treatment of fistulising perianal Crohn's disease. Aliment Pharmacol Ther. 40(7):741-9, 2014
Baker ME et al: Mural attenuation in normal small bowel and active inflammatory Crohn's disease on CT enterography: location, absolute attenuation, relative attenuation, and the effect of wall thickness. AJR Am J Roentgenol. 192(2):417-23, 2009
Lee SS et al: Crohn disease of the small bowel: comparison of CT enterography, MR enterography, and small-bowel follow-through as diagnostic techniques. Radiology. 251(3):751-61, 2009
Amitai MM et al: Multislice CT compared to small bowel follow-through in the evaluation of patients with Crohn disease. Clin Imaging. 32(5):355-61, 2008
Bruining DH et al: Prevalence of penetrating disease and extraintestinal manifestations of Crohn's disease detected with CT enterography. Inflamm Bowel Dis. 14(12):1701-6, 2008
Hara AK et al: Using CT enterography to monitor Crohn's disease activity: a preliminary study. AJR Am J Roentgenol. 190(6):1512-6, 2008
Solem CA et al: Small-bowel imaging in Crohn's disease: a prospective, blinded, 4-way comparison trial. Gastrointest Endosc. 68(2):255-66, 2008
Bodily KD et al: Crohn Disease: mural attenuation and thickness at contrast-enhanced CT enterography--correlation with endoscopic and histologic findings of inflammation. Radiology. 238(2):505-16, 2006
Wold PB et al: Assessment of small bowel Crohn disease: noninvasive peroral CT enterography compared with other imaging methods and endoscopy--feasibility study. Radiology. 229(1):275-81, 2003
Low RN et al: Crohn disease with endoscopic correlation: single-shot fast spin-echo and gadolinium-enhanced fat-suppressed spoiled gradient-echo MR imaging. Radiology. 222(3):652-60, 2002
Antes G: [Inflammatory bowel diseases. Colon contrast enema and CT] Radiologe. 38(1):41-9, 1998
Gore RM et al: CT features of ulcerative colitis and Crohn's disease. AJR Am J Roentgenol. 167(1):3-15, 1996
Hizawa K et al: Crohn disease: early recognition and progress of aphthous lesions. Radiology. 190(2):451-4, 1994
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
Terminal ileitis, regional enteritis, ileocolitis
Definitions
Disease of unknown etiology characterized by transmural inflammation of GI tract
IMAGING
General Features
Fluoroscopic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Other Modality Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Guglielmo FF et al: Small bowel crohn disease at CT and MR enterography: imaging atlas and glossary of terms. Radiographics. 40(2):354-75, 2020
Bruining DH et al: Consensus recommendations for evaluation, interpretation, and utilization of computed tomography and magnetic resonance enterography in patients with small bowel Crohn's disease. Radiology. 286(3):776-99, 2018
Gajendran M et al: A comprehensive review and update on Crohn's disease. Dis Mon. 64(2):20-57, 2018
Gomollón F et al: 3rd European evidence-based consensus on the diagnosis and management of crohn's disease 2016: part 1: diagnosis and medical management. J Crohns Colitis. 11(1):3-25, 2017
Allen BC et al: MR enterography for assessment and management of small bowel Crohn disease. Radiol Clin North Am. 52(4):799-810, 2014
Mandel MD et al: Have biologics changed the natural history of Crohn's disease? Dig Dis. 32(4):351-9, 2014
Marineaţă A et al: Extra intestinal manifestations and complications in inflammatory bowel disease. Rev Med Chir Soc Med Nat Iasi. 118(2):279-88, 2014
Qiu Y et al: Systematic review with meta-analysis: magnetic resonance enterography vs. computed tomography enterography for evaluating disease activity in small bowel Crohn's disease. Aliment Pharmacol Ther. 40(2):134-46, 2014
Rodriguez P et al: Imaging Crohn disease: MR enterography. J Comput Assist Tomogr. 38(2):219-27, 2014
Yassin NA et al: Systematic review: the combined surgical and medical treatment of fistulising perianal Crohn's disease. Aliment Pharmacol Ther. 40(7):741-9, 2014
Baker ME et al: Mural attenuation in normal small bowel and active inflammatory Crohn's disease on CT enterography: location, absolute attenuation, relative attenuation, and the effect of wall thickness. AJR Am J Roentgenol. 192(2):417-23, 2009
Lee SS et al: Crohn disease of the small bowel: comparison of CT enterography, MR enterography, and small-bowel follow-through as diagnostic techniques. Radiology. 251(3):751-61, 2009
Amitai MM et al: Multislice CT compared to small bowel follow-through in the evaluation of patients with Crohn disease. Clin Imaging. 32(5):355-61, 2008
Bruining DH et al: Prevalence of penetrating disease and extraintestinal manifestations of Crohn's disease detected with CT enterography. Inflamm Bowel Dis. 14(12):1701-6, 2008
Hara AK et al: Using CT enterography to monitor Crohn's disease activity: a preliminary study. AJR Am J Roentgenol. 190(6):1512-6, 2008
Solem CA et al: Small-bowel imaging in Crohn's disease: a prospective, blinded, 4-way comparison trial. Gastrointest Endosc. 68(2):255-66, 2008
Bodily KD et al: Crohn Disease: mural attenuation and thickness at contrast-enhanced CT enterography--correlation with endoscopic and histologic findings of inflammation. Radiology. 238(2):505-16, 2006
Wold PB et al: Assessment of small bowel Crohn disease: noninvasive peroral CT enterography compared with other imaging methods and endoscopy--feasibility study. Radiology. 229(1):275-81, 2003
Low RN et al: Crohn disease with endoscopic correlation: single-shot fast spin-echo and gadolinium-enhanced fat-suppressed spoiled gradient-echo MR imaging. Radiology. 222(3):652-60, 2002
Antes G: [Inflammatory bowel diseases. Colon contrast enema and CT] Radiologe. 38(1):41-9, 1998
Gore RM et al: CT features of ulcerative colitis and Crohn's disease. AJR Am J Roentgenol. 167(1):3-15, 1996
Hizawa K et al: Crohn disease: early recognition and progress of aphthous lesions. Radiology. 190(2):451-4, 1994
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