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Crohn Disease
Alexandra Medellin, MD; Stephanie R. Wilson, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Diagnostic Checklist

        TERMINOLOGY

        • Synonyms

          • Terminal ileitis, regional enteritis, ileocolitis
        • Definitions

          • Chronic, relapsing inflammatory process that affects any part of GI tract

        IMAGING

        • General Features

          • Ultrasonographic Findings

            • Fluoroscopic Findings

              • CT Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    Selected References

                                    1. Lu C et al: Bowel ultrasound state of the art: grayscale and Doppler ultrasound, contrast enhancement, and elastography in Crohn disease. J Ultrasound Med. 38(2):271-88, 2019
                                    2. Maconi G et al: EFSUMB recommendations and clinical guidelines for intestinal ultrasound (GIUS) in inflammatory bowel diseases. Ultraschall Med. 39(3):304-17, 2018
                                    3. Medellin A et al: Role of contrast-enhanced ultrasound in evaluation of the bowel. Abdom Radiol (NY). 43(4):918-33, 2018
                                    4. Baumgart DC et al: US-based real-time elastography for the detection of fibrotic gut tissue in patients with stricturing Crohn disease. Radiology. 275(3):889-99, 2015
                                    5. Anupindi SA et al: Common and uncommon applications of bowel ultrasound with pathologic correlation in children. AJR Am J Roentgenol. 202(5):946-59, 2014
                                    6. Anupindi SA et al: Imaging in the evaluation of the young patient with inflammatory bowel disease: what the gastroenterologist needs to know. J Pediatr Gastroenterol Nutr. 59(4):429-39, 2014
                                    7. Cosgrove D et al: EFSUMB guidelines and recommendations on the clinical use of ultrasound elastography. Part 2: clinical applications. Ultraschall Med. 34(3):238-53, 2013
                                    8. Novak KL et al: The role of ultrasound in the evaluation of inflammatory bowel disease. Semin Roentgenol. 48(3):224-33, 2013
                                    9. Rodgers PM et al: Transabdominal ultrasound for bowel evaluation. Radiol Clin North Am. 51(1):133-48, 2013
                                    10. Abraham BP et al: Fecal markers: calprotectin and lactoferrin. Gastroenterol Clin North Am. 41(2):483-95, 2012
                                    11. Anupindi SA et al: Bowel imaging in children: a comprehensive look using US and MRI. Semin Roentgenol. 47(2):118-26, 2012
                                    12. Baumgart DC et al: Crohn's disease. Lancet. 380(9853):1590-605, 2012
                                    13. Maturen KE et al: Ultrasound imaging of bowel pathology: technique and keys to diagnosis in the acute abdomen. AJR Am J Roentgenol. 197(6):W1067-75, 2011
                                    14. Darge K et al: Ultrasound of the bowel in children: how we do it. Pediatr Radiol. 40(4):528-36, 2010
                                    15. Anupindi SA et al: Imaging choices in inflammatory bowel disease. Pediatr Radiol. 39 Suppl 2:S149-52, 2009
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Diagnostic Checklist

                                          TERMINOLOGY

                                          • Synonyms

                                            • Terminal ileitis, regional enteritis, ileocolitis
                                          • Definitions

                                            • Chronic, relapsing inflammatory process that affects any part of GI tract

                                          IMAGING

                                          • General Features

                                            • Ultrasonographic Findings

                                              • Fluoroscopic Findings

                                                • CT Findings

                                                  • MR Findings

                                                    • Imaging Recommendations

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • General Features

                                                          • Gross Pathologic & Surgical Features

                                                            CLINICAL ISSUES

                                                            • Presentation

                                                              • Demographics

                                                                • Natural History & Prognosis

                                                                  • Treatment

                                                                    DIAGNOSTIC CHECKLIST

                                                                    • Consider

                                                                      Selected References

                                                                      1. Lu C et al: Bowel ultrasound state of the art: grayscale and Doppler ultrasound, contrast enhancement, and elastography in Crohn disease. J Ultrasound Med. 38(2):271-88, 2019
                                                                      2. Maconi G et al: EFSUMB recommendations and clinical guidelines for intestinal ultrasound (GIUS) in inflammatory bowel diseases. Ultraschall Med. 39(3):304-17, 2018
                                                                      3. Medellin A et al: Role of contrast-enhanced ultrasound in evaluation of the bowel. Abdom Radiol (NY). 43(4):918-33, 2018
                                                                      4. Baumgart DC et al: US-based real-time elastography for the detection of fibrotic gut tissue in patients with stricturing Crohn disease. Radiology. 275(3):889-99, 2015
                                                                      5. Anupindi SA et al: Common and uncommon applications of bowel ultrasound with pathologic correlation in children. AJR Am J Roentgenol. 202(5):946-59, 2014
                                                                      6. Anupindi SA et al: Imaging in the evaluation of the young patient with inflammatory bowel disease: what the gastroenterologist needs to know. J Pediatr Gastroenterol Nutr. 59(4):429-39, 2014
                                                                      7. Cosgrove D et al: EFSUMB guidelines and recommendations on the clinical use of ultrasound elastography. Part 2: clinical applications. Ultraschall Med. 34(3):238-53, 2013
                                                                      8. Novak KL et al: The role of ultrasound in the evaluation of inflammatory bowel disease. Semin Roentgenol. 48(3):224-33, 2013
                                                                      9. Rodgers PM et al: Transabdominal ultrasound for bowel evaluation. Radiol Clin North Am. 51(1):133-48, 2013
                                                                      10. Abraham BP et al: Fecal markers: calprotectin and lactoferrin. Gastroenterol Clin North Am. 41(2):483-95, 2012
                                                                      11. Anupindi SA et al: Bowel imaging in children: a comprehensive look using US and MRI. Semin Roentgenol. 47(2):118-26, 2012
                                                                      12. Baumgart DC et al: Crohn's disease. Lancet. 380(9853):1590-605, 2012
                                                                      13. Maturen KE et al: Ultrasound imaging of bowel pathology: technique and keys to diagnosis in the acute abdomen. AJR Am J Roentgenol. 197(6):W1067-75, 2011
                                                                      14. Darge K et al: Ultrasound of the bowel in children: how we do it. Pediatr Radiol. 40(4):528-36, 2010
                                                                      15. Anupindi SA et al: Imaging choices in inflammatory bowel disease. Pediatr Radiol. 39 Suppl 2:S149-52, 2009