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Cyanide Poisoning
Miral D. Jhaveri, MD; Sheri L. Harder, MD, FRCPC
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Cyanide (CN) poisoning
              • Definitions

                • Anoxic encephalopathy caused by exposure to CN

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Imaging Recommendations

                      • Nuclear Medicine Findings

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        Selected References

                                        1. Borron SW et al: Asphyxiants. Emerg Med Clin North Am. 33(1):89-115, 2015
                                        2. Weaver LK: Hyperbaric oxygen therapy for carbon monoxide poisoning. Undersea Hyperb Med. 41(4):339-54, 2014
                                        3. Dries DJ et al: Inhalation injury: epidemiology, pathology, treatment strategies. Scand J Trauma Resusc Emerg Med. 21:31, 2013
                                        4. Huzar TF et al: Carbon monoxide and cyanide toxicity: etiology, pathophysiology and treatment in inhalation injury. Expert Rev Respir Med. 7(2):159-70, 2013
                                        5. Baud FJ: [Acute poisoning with carbon monoxide (CO) and cyanide (CN).] Ther Umsch. 66(5):387-97, 2009
                                        6. Bronstein AC et al: 2007 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 25th Annual Report. Clin Toxicol (Phila). 46(10):927-1057, 2008
                                        7. Baud FJ: Cyanide: critical issues in diagnosis and treatment. Hum Exp Toxicol. 26(3):191-201, 2007
                                        8. Hantson P et al: The value of morphological neuroimaging after acute exposure to toxic substances. Toxicol Rev. 25(2):87-98, 2006
                                        9. Rachinger J et al: MR changes after acute cyanide intoxication. AJNR Am J Neuroradiol. 23(8):1398-401, 2002
                                        10. Borgohain R et al: Delayed onset generalised dystonia after cyanide poisoning. Clin Neurol Neurosurg. 97(3):213-5, 1995
                                        11. Rosenow F et al: Neurological sequelae of cyanide intoxication--the patterns of clinical, magnetic resonance imaging, and positron emission tomography findings. Ann Neurol. 38(5):825-8, 1995
                                        12. Kasamo K et al: Chronological changes of MRI findings on striatal damage after acute cyanide intoxication: pathogenesis of the damage and its selectivity, and prevention for neurological sequelae: a case report. Eur Arch Psychiatry Clin Neurosci. 243(2):71-4, 1993
                                        13. Feldman JM et al: Sequelae of attempted suicide by cyanide ingestion: a case report. Int J Psychiatry Med. 20(2):173-9, 1990
                                        14. Carella F et al: Dystonic-Parkinsonian syndrome after cyanide poisoning: clinical and MRI findings. J Neurol Neurosurg Psychiatry. 51(10):1345-8, 1988
                                        15. Messing B et al: Computer tomography and magnetic resonance imaging in cyanide poisoning. Eur Arch Psychiatry Neurol Sci. 237(3):139-43, 1988
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Cyanide (CN) poisoning
                                                    • Definitions

                                                      • Anoxic encephalopathy caused by exposure to CN

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Imaging Recommendations

                                                            • Nuclear Medicine Findings

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              Selected References

                                                                              1. Borron SW et al: Asphyxiants. Emerg Med Clin North Am. 33(1):89-115, 2015
                                                                              2. Weaver LK: Hyperbaric oxygen therapy for carbon monoxide poisoning. Undersea Hyperb Med. 41(4):339-54, 2014
                                                                              3. Dries DJ et al: Inhalation injury: epidemiology, pathology, treatment strategies. Scand J Trauma Resusc Emerg Med. 21:31, 2013
                                                                              4. Huzar TF et al: Carbon monoxide and cyanide toxicity: etiology, pathophysiology and treatment in inhalation injury. Expert Rev Respir Med. 7(2):159-70, 2013
                                                                              5. Baud FJ: [Acute poisoning with carbon monoxide (CO) and cyanide (CN).] Ther Umsch. 66(5):387-97, 2009
                                                                              6. Bronstein AC et al: 2007 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 25th Annual Report. Clin Toxicol (Phila). 46(10):927-1057, 2008
                                                                              7. Baud FJ: Cyanide: critical issues in diagnosis and treatment. Hum Exp Toxicol. 26(3):191-201, 2007
                                                                              8. Hantson P et al: The value of morphological neuroimaging after acute exposure to toxic substances. Toxicol Rev. 25(2):87-98, 2006
                                                                              9. Rachinger J et al: MR changes after acute cyanide intoxication. AJNR Am J Neuroradiol. 23(8):1398-401, 2002
                                                                              10. Borgohain R et al: Delayed onset generalised dystonia after cyanide poisoning. Clin Neurol Neurosurg. 97(3):213-5, 1995
                                                                              11. Rosenow F et al: Neurological sequelae of cyanide intoxication--the patterns of clinical, magnetic resonance imaging, and positron emission tomography findings. Ann Neurol. 38(5):825-8, 1995
                                                                              12. Kasamo K et al: Chronological changes of MRI findings on striatal damage after acute cyanide intoxication: pathogenesis of the damage and its selectivity, and prevention for neurological sequelae: a case report. Eur Arch Psychiatry Clin Neurosci. 243(2):71-4, 1993
                                                                              13. Feldman JM et al: Sequelae of attempted suicide by cyanide ingestion: a case report. Int J Psychiatry Med. 20(2):173-9, 1990
                                                                              14. Carella F et al: Dystonic-Parkinsonian syndrome after cyanide poisoning: clinical and MRI findings. J Neurol Neurosurg Psychiatry. 51(10):1345-8, 1988
                                                                              15. Messing B et al: Computer tomography and magnetic resonance imaging in cyanide poisoning. Eur Arch Psychiatry Neurol Sci. 237(3):139-43, 1988