Presence of 3 or more renal cysts per kidney in patients with chronic kidney disease (CKD) who do not have hereditary cystic disease
Occurs predominantly in patients on long-term dialysis (peritoneal or hemodialysis)
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Hashimoto M et al: Usefulness of contrast-enhanced ultrasonography for diagnosis of renal cell carcinoma in dialysis patients: comparison with computed tomography. Medicine (Baltimore). 98(47):e18053, 2019
Rahbari-Oskoui F et al: Diagnosis and management of acquired cystic kidney disease and renal tumors in ESRD patients. Semin Dial. 30(4):373-9, 2017
Wood CG 3rd et al: CT and MR imaging for evaluation of cystic renal lesions and diseases. Radiographics. 35(1):125-41, 2015
Cokkinos DD et al: Contrast enhanced ultrasound of the kidneys: what is it capable of? Biomed Res Int. 2013:595873, 2013
Singanamala S et al: Should screening for acquired cystic disease and renal malignancy be undertaken in dialysis patients? Semin Dial. 24(4):365-6, 2011
Katabathina VS et al: Adult renal cystic disease: a genetic, biological, and developmental primer. Radiographics. 30(6):1509-23, 2010
Ishikawa I et al: Twenty-year follow-up of acquired renal cystic disease. Clin Nephrol. 59(3):153-9, 2003
Neureiter D et al: Dialysis-associated acquired cystic kidney disease imitating autosomal dominant polycystic kidney disease in a patient receiving long-term peritoneal dialysis. Nephrol Dial Transplant. 17(3):500-3, 2002
Chatha RK et al: Von Hippel-Lindau disease masquerading as autosomal dominant polycystic kidney disease. Am J Kidney Dis. 37(4):852-8, 2001
Nascimento AB et al: Rapid MR imaging detection of renal cysts: age-based standards. Radiology. 221(3):628-32, 2001
Slywotzky CM et al: Localized cystic disease of the kidney. AJR Am J Roentgenol. 176(4):843-9, 2001
Hughson MD et al: Renal cell carcinoma of end-stage renal disease: an analysis of chromosome 3, 7, and 17 abnormalities by microsatellite amplification. Mod Pathol. 12(3):301-9, 1999
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References
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Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Abbreviations
Acquired cystic kidney disease (ACKD)
Synonyms
Acquired cystic disease of uremia
Definitions
Presence of 3 or more renal cysts per kidney in patients with chronic kidney disease (CKD) who do not have hereditary cystic disease
Occurs predominantly in patients on long-term dialysis (peritoneal or hemodialysis)
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Hashimoto M et al: Usefulness of contrast-enhanced ultrasonography for diagnosis of renal cell carcinoma in dialysis patients: comparison with computed tomography. Medicine (Baltimore). 98(47):e18053, 2019
Rahbari-Oskoui F et al: Diagnosis and management of acquired cystic kidney disease and renal tumors in ESRD patients. Semin Dial. 30(4):373-9, 2017
Wood CG 3rd et al: CT and MR imaging for evaluation of cystic renal lesions and diseases. Radiographics. 35(1):125-41, 2015
Cokkinos DD et al: Contrast enhanced ultrasound of the kidneys: what is it capable of? Biomed Res Int. 2013:595873, 2013
Singanamala S et al: Should screening for acquired cystic disease and renal malignancy be undertaken in dialysis patients? Semin Dial. 24(4):365-6, 2011
Katabathina VS et al: Adult renal cystic disease: a genetic, biological, and developmental primer. Radiographics. 30(6):1509-23, 2010
Ishikawa I et al: Twenty-year follow-up of acquired renal cystic disease. Clin Nephrol. 59(3):153-9, 2003
Neureiter D et al: Dialysis-associated acquired cystic kidney disease imitating autosomal dominant polycystic kidney disease in a patient receiving long-term peritoneal dialysis. Nephrol Dial Transplant. 17(3):500-3, 2002
Chatha RK et al: Von Hippel-Lindau disease masquerading as autosomal dominant polycystic kidney disease. Am J Kidney Dis. 37(4):852-8, 2001
Nascimento AB et al: Rapid MR imaging detection of renal cysts: age-based standards. Radiology. 221(3):628-32, 2001
Slywotzky CM et al: Localized cystic disease of the kidney. AJR Am J Roentgenol. 176(4):843-9, 2001
Hughson MD et al: Renal cell carcinoma of end-stage renal disease: an analysis of chromosome 3, 7, and 17 abnormalities by microsatellite amplification. Mod Pathol. 12(3):301-9, 1999
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