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Cystic Fibrosis, Gastrointestinal Tract
Alexander J. Towbin, MD
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KEY FACTS

  • Terminology

    • Imaging

      TERMINOLOGY

      • Definitions

        • Cystic fibrosis (CF): Autosomal recessive multisystem disorder caused by dysfunctional chloride ion transport across epithelial surfaces
          • Presenting symptoms of CF in infants & young children most commonly GI related

      IMAGING

      • General Features

        • Radiographic Findings

          • Fluoroscopic Findings

            • CT Findings

              • MR Findings

                • Ultrasonographic Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Natural History & Prognosis

                              • Treatment

                                DIAGNOSTIC CHECKLIST

                                • Consider

                                  Selected References

                                  1. Assis DN et al: Gastrointestinal disorders in cystic fibrosis. Clin Chest Med. 37(1):109-18, 2016
                                  2. Working Party of the Australasian Pancreatic Club et al: Summary and recommendations from the Australasian guidelines for the management of pancreatic exocrine insufficiency. Pancreatology. 16(2): 164-80, 2016
                                  3. Kelly T et al: Gastrointestinal manifestations of cystic fibrosis. Dig Dis Sci. 60(7):1903-13, 2015
                                  4. Lavelle LP et al: Cystic fibrosis below the diaphragm: abdominal findings in adult patients. Radiographics. 35(3):680-95, 2015
                                  5. Leung DH et al: Baseline ultrasound and clinical correlates in children with cystic fibrosis. J Pediatr. 167(4):862-868.e2, 2015
                                  6. Munck A et al: Management of pancreatic, gastrointestinal and liver complications in adult cystic fibrosis. Rev Mal Respir. 32(6):566-85, 2015
                                  7. Caldaro T et al: Cystic fibrosis: a surgical matter? J Pediatr Surg. 49(5):753-8, 2014
                                  8. Gelfond D et al: Gastrointestinal complications of cystic fibrosis. Clin Gastroenterol Hepatol. 11(4):333-42; quiz e30-1, 2013
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  KEY FACTS

                                  • Terminology

                                    • Imaging

                                      TERMINOLOGY

                                      • Definitions

                                        • Cystic fibrosis (CF): Autosomal recessive multisystem disorder caused by dysfunctional chloride ion transport across epithelial surfaces
                                          • Presenting symptoms of CF in infants & young children most commonly GI related

                                      IMAGING

                                      • General Features

                                        • Radiographic Findings

                                          • Fluoroscopic Findings

                                            • CT Findings

                                              • MR Findings

                                                • Ultrasonographic Findings

                                                  • Imaging Recommendations

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        CLINICAL ISSUES

                                                        • Presentation

                                                          • Demographics

                                                            • Natural History & Prognosis

                                                              • Treatment

                                                                DIAGNOSTIC CHECKLIST

                                                                • Consider

                                                                  Selected References

                                                                  1. Assis DN et al: Gastrointestinal disorders in cystic fibrosis. Clin Chest Med. 37(1):109-18, 2016
                                                                  2. Working Party of the Australasian Pancreatic Club et al: Summary and recommendations from the Australasian guidelines for the management of pancreatic exocrine insufficiency. Pancreatology. 16(2): 164-80, 2016
                                                                  3. Kelly T et al: Gastrointestinal manifestations of cystic fibrosis. Dig Dis Sci. 60(7):1903-13, 2015
                                                                  4. Lavelle LP et al: Cystic fibrosis below the diaphragm: abdominal findings in adult patients. Radiographics. 35(3):680-95, 2015
                                                                  5. Leung DH et al: Baseline ultrasound and clinical correlates in children with cystic fibrosis. J Pediatr. 167(4):862-868.e2, 2015
                                                                  6. Munck A et al: Management of pancreatic, gastrointestinal and liver complications in adult cystic fibrosis. Rev Mal Respir. 32(6):566-85, 2015
                                                                  7. Caldaro T et al: Cystic fibrosis: a surgical matter? J Pediatr Surg. 49(5):753-8, 2014
                                                                  8. Gelfond D et al: Gastrointestinal complications of cystic fibrosis. Clin Gastroenterol Hepatol. 11(4):333-42; quiz e30-1, 2013