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Cystic Hygroma
Roya Sohaey, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Cystic hygroma (CH)
            • Synonyms

              • Nuchal lymphangioma
              • Nuchal cystic hygromata
            • Definitions

              • Mono- or multiloculated lymphatic system anomaly causing abnormal nuchal fluid collection

            IMAGING

            • General Features

              • Ultrasonographic Findings

                • Imaging Recommendations

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Microscopic Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Natural History & Prognosis

                              • Treatment

                                DIAGNOSTIC CHECKLIST

                                • Consider

                                  • Image Interpretation Pearls

                                    • Reporting Tips

                                      Selected References

                                      1. Aymelek HS et al: Genetic burden and outcome of cystic hygromas detected antenatally: results of 93 pregnancies from a single center in the northern region of Turkey. J Med Ultrasound. 27(4):181-6, 2019
                                      2. Noia G et al: Cystic hygroma: a preliminary genetic study and a short review from the literature. Lymphat Res Biol. 17(1):30-9, 2019
                                      3. Schreurs L et al: First trimester cystic hygroma colli: retrospective analysis in a tertiary center. Eur J Obstet Gynecol Reprod Biol. 231:60-4, 2018
                                      4. Chen YN et al: Prenatal ultrasound evaluation and outcome of pregnancy with fetal cystic hygromas and lymphangiomas. J Med Ultrasound. 25(1):12-5, 2017
                                      5. Scholl J et al: First trimester cystic hygroma: does early detection matter? Prenat Diagn. 36(5):432-6, 2016
                                      6. Malone LJ et al: Pediatric lymphangiectasia: an imaging spectrum. Pediatr Radiol. 45(4):562-9, 2015
                                      7. Chen M et al: Cystic hygroma detected in the first trimester scan in Hong Kong. J Matern Fetal Neonatal Med. 27(4):342-5, 2014
                                      8. Noia G et al: Fetal cystic hygroma: the importance of natural history. Eur J Obstet Gynecol Reprod Biol. 170(2):407-13, 2013
                                      9. Scholl J et al: First-trimester cystic hygroma: relationship of nuchal translucency thickness and outcomes. Obstet Gynecol. 120(3):551-9, 2012
                                      10. Sananes N et al: Nuchal translucency and cystic hygroma colli in screening for fetal major congenital heart defects in a series of 12,910 euploid pregnancies. Ultrasound Obstet Gynecol. 35(3):273-9, 2010
                                      11. Gedikbasi A et al: Multidisciplinary approach in cystic hygroma: prenatal diagnosis, outcome, and postnatal follow up. Pediatr Int. 51(5):670-7, 2009
                                      12. Howarth ES et al: Population-based study of the outcome following the prenatal diagnosis of cystic hygroma. Prenat Diagn. 25(4):286-91, 2005
                                      13. Ganapathy R et al: Natural history and outcome of prenatally diagnosed cystic hygroma. Prenat Diagn. 24(12):965-8, 2004
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Clinical Issues

                                              • Diagnostic Checklist

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Cystic hygroma (CH)
                                                • Synonyms

                                                  • Nuchal lymphangioma
                                                  • Nuchal cystic hygromata
                                                • Definitions

                                                  • Mono- or multiloculated lymphatic system anomaly causing abnormal nuchal fluid collection

                                                IMAGING

                                                • General Features

                                                  • Ultrasonographic Findings

                                                    • Imaging Recommendations

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • General Features

                                                          • Microscopic Features

                                                            CLINICAL ISSUES

                                                            • Presentation

                                                              • Demographics

                                                                • Natural History & Prognosis

                                                                  • Treatment

                                                                    DIAGNOSTIC CHECKLIST

                                                                    • Consider

                                                                      • Image Interpretation Pearls

                                                                        • Reporting Tips

                                                                          Selected References

                                                                          1. Aymelek HS et al: Genetic burden and outcome of cystic hygromas detected antenatally: results of 93 pregnancies from a single center in the northern region of Turkey. J Med Ultrasound. 27(4):181-6, 2019
                                                                          2. Noia G et al: Cystic hygroma: a preliminary genetic study and a short review from the literature. Lymphat Res Biol. 17(1):30-9, 2019
                                                                          3. Schreurs L et al: First trimester cystic hygroma colli: retrospective analysis in a tertiary center. Eur J Obstet Gynecol Reprod Biol. 231:60-4, 2018
                                                                          4. Chen YN et al: Prenatal ultrasound evaluation and outcome of pregnancy with fetal cystic hygromas and lymphangiomas. J Med Ultrasound. 25(1):12-5, 2017
                                                                          5. Scholl J et al: First trimester cystic hygroma: does early detection matter? Prenat Diagn. 36(5):432-6, 2016
                                                                          6. Malone LJ et al: Pediatric lymphangiectasia: an imaging spectrum. Pediatr Radiol. 45(4):562-9, 2015
                                                                          7. Chen M et al: Cystic hygroma detected in the first trimester scan in Hong Kong. J Matern Fetal Neonatal Med. 27(4):342-5, 2014
                                                                          8. Noia G et al: Fetal cystic hygroma: the importance of natural history. Eur J Obstet Gynecol Reprod Biol. 170(2):407-13, 2013
                                                                          9. Scholl J et al: First-trimester cystic hygroma: relationship of nuchal translucency thickness and outcomes. Obstet Gynecol. 120(3):551-9, 2012
                                                                          10. Sananes N et al: Nuchal translucency and cystic hygroma colli in screening for fetal major congenital heart defects in a series of 12,910 euploid pregnancies. Ultrasound Obstet Gynecol. 35(3):273-9, 2010
                                                                          11. Gedikbasi A et al: Multidisciplinary approach in cystic hygroma: prenatal diagnosis, outcome, and postnatal follow up. Pediatr Int. 51(5):670-7, 2009
                                                                          12. Howarth ES et al: Population-based study of the outcome following the prenatal diagnosis of cystic hygroma. Prenat Diagn. 25(4):286-91, 2005
                                                                          13. Ganapathy R et al: Natural history and outcome of prenatally diagnosed cystic hygroma. Prenat Diagn. 24(12):965-8, 2004