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Dedifferentiated Liposarcoma
Catherine C. Roberts, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Definitions

            • Malignant fatty tumor showing transition from well-differentiated liposarcoma to nonlipogenic sarcoma
              • Bimorphic lesion with variable histologic grade of dedifferentiated portion

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Gross Pathologic & Surgical Features

                        • Microscopic Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  Selected References

                                  1. Shanbhogue AK et al: Uncommon primary pelvic retroperitoneal masses in adults: a pattern-based imaging approach. Radiographics. 32(3):795-817, 2012
                                  2. Craig WD et al: Fat-containing lesions of the retroperitoneum: radiologic-pathologic correlation. Radiographics. 29(1):261-90, 2009
                                  3. Weiss SW et al: Liposarcoma. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier. 493-8, 2008
                                  4. Dei Tos AP et al: Dedifferentiated liposarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 38-9; 2002
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  KEY FACTS

                                  • Terminology

                                    • Imaging

                                      • Pathology

                                        • Clinical Issues

                                          TERMINOLOGY

                                          • Definitions

                                            • Malignant fatty tumor showing transition from well-differentiated liposarcoma to nonlipogenic sarcoma
                                              • Bimorphic lesion with variable histologic grade of dedifferentiated portion

                                          IMAGING

                                          • General Features

                                            • Radiographic Findings

                                              • CT Findings

                                                • MR Findings

                                                  DIFFERENTIAL DIAGNOSIS

                                                    PATHOLOGY

                                                    • General Features

                                                      • Gross Pathologic & Surgical Features

                                                        • Microscopic Features

                                                          CLINICAL ISSUES

                                                          • Presentation

                                                            • Demographics

                                                              • Natural History & Prognosis

                                                                • Treatment

                                                                  Selected References

                                                                  1. Shanbhogue AK et al: Uncommon primary pelvic retroperitoneal masses in adults: a pattern-based imaging approach. Radiographics. 32(3):795-817, 2012
                                                                  2. Craig WD et al: Fat-containing lesions of the retroperitoneum: radiologic-pathologic correlation. Radiographics. 29(1):261-90, 2009
                                                                  3. Weiss SW et al: Liposarcoma. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier. 493-8, 2008
                                                                  4. Dei Tos AP et al: Dedifferentiated liposarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 38-9; 2002