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Default Mode Network
Jeffrey S. Anderson, MD, PhD
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Imaging Anatomy

  • Overview

    • Network Hubs

      • Function

        Anatomy Imaging Issues

        • Imaging Recommendations

          • Imaging Pitfalls

            Clinical Implications

            • Clinical Importance

              Selected References

              1. Anticevic A et al: The role of default network deactivation in cognition and disease. Trends Cogn Sci. 16(12):584-92, 2012
              2. Buckner RL: The serendipitous discovery of the brain's default network. Neuroimage. 62(2):1137-45, 2012
              3. Spencer MD et al: Failure to deactivate the default mode network indicates a possible endophenotype of autism. Mol Autism. 3(1):15, 2012
              4. Sestieri C et al: Episodic memory retrieval, parietal cortex, and the default mode network: functional and topographic analyses. J Neurosci. 31(12):4407-20, 2011
              5. Andrews-Hanna JR et al: Functional-anatomic fractionation of the brain's default network. Neuron. 65(4):550-62, 2010
              6. Sheline YI et al: Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly. Biol Psychiatry. 67(6):584-7, 2010
              7. Spreng RN et al: Patterns of brain activity supporting autobiographical memory, prospection, and theory of mind, and their relationship to the default mode network. J Cogn Neurosci. 22(6):1112-23, 2010
              8. Sheline YI et al: The default mode network and self-referential processes in depression. Proc Natl Acad Sci U S A. 106(6):1942-7, 2009
              9. Uddin LQ et al: Functional connectivity of default mode network components: correlation, anticorrelation, and causality. Hum Brain Mapp. 30(2):625-37, 2009
              10. Buckner RL et al: The brain's default network: anatomy, function, and relevance to disease. Ann N Y Acad Sci. 1124:1-38, 2008
              11. Fair DA et al: The maturing architecture of the brain's default network. Proc Natl Acad Sci U S A. 105(10):4028-32, 2008
              12. Fransson P et al: The precuneus/posterior cingulate cortex plays a pivotal role in the default mode network: Evidence from a partial correlation network analysis. Neuroimage. 42(3):1178-84, 2008
              13. Harrison BJ et al: Consistency and functional specialization in the default mode brain network. Proc Natl Acad Sci U S A. 105(28):9781-6, 2008
              14. Mason MF et al: Wandering minds: the default network and stimulus-independent thought. Science. 315(5810):393-5, 2007
              15. Raichle ME et al: A default mode of brain function: a brief history of an evolving idea. Neuroimage. 37(4):1083-90; discussion 1097-9, 2007
              16. Greicius MD et al: Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci U S A. 101(13):4637-42, 2004
              17. Greicius MD et al: Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci U S A. 100(1):253-8, 2003
              18. Raichle ME et al: A default mode of brain function. Proc Natl Acad Sci U S A. 98(2):676-82, 2001
              Related Anatomy
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              References
              Tables

              Tables

              Imaging Anatomy

              • Overview

                • Network Hubs

                  • Function

                    Anatomy Imaging Issues

                    • Imaging Recommendations

                      • Imaging Pitfalls

                        Clinical Implications

                        • Clinical Importance

                          Selected References

                          1. Anticevic A et al: The role of default network deactivation in cognition and disease. Trends Cogn Sci. 16(12):584-92, 2012
                          2. Buckner RL: The serendipitous discovery of the brain's default network. Neuroimage. 62(2):1137-45, 2012
                          3. Spencer MD et al: Failure to deactivate the default mode network indicates a possible endophenotype of autism. Mol Autism. 3(1):15, 2012
                          4. Sestieri C et al: Episodic memory retrieval, parietal cortex, and the default mode network: functional and topographic analyses. J Neurosci. 31(12):4407-20, 2011
                          5. Andrews-Hanna JR et al: Functional-anatomic fractionation of the brain's default network. Neuron. 65(4):550-62, 2010
                          6. Sheline YI et al: Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly. Biol Psychiatry. 67(6):584-7, 2010
                          7. Spreng RN et al: Patterns of brain activity supporting autobiographical memory, prospection, and theory of mind, and their relationship to the default mode network. J Cogn Neurosci. 22(6):1112-23, 2010
                          8. Sheline YI et al: The default mode network and self-referential processes in depression. Proc Natl Acad Sci U S A. 106(6):1942-7, 2009
                          9. Uddin LQ et al: Functional connectivity of default mode network components: correlation, anticorrelation, and causality. Hum Brain Mapp. 30(2):625-37, 2009
                          10. Buckner RL et al: The brain's default network: anatomy, function, and relevance to disease. Ann N Y Acad Sci. 1124:1-38, 2008
                          11. Fair DA et al: The maturing architecture of the brain's default network. Proc Natl Acad Sci U S A. 105(10):4028-32, 2008
                          12. Fransson P et al: The precuneus/posterior cingulate cortex plays a pivotal role in the default mode network: Evidence from a partial correlation network analysis. Neuroimage. 42(3):1178-84, 2008
                          13. Harrison BJ et al: Consistency and functional specialization in the default mode brain network. Proc Natl Acad Sci U S A. 105(28):9781-6, 2008
                          14. Mason MF et al: Wandering minds: the default network and stimulus-independent thought. Science. 315(5810):393-5, 2007
                          15. Raichle ME et al: A default mode of brain function: a brief history of an evolving idea. Neuroimage. 37(4):1083-90; discussion 1097-9, 2007
                          16. Greicius MD et al: Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci U S A. 101(13):4637-42, 2004
                          17. Greicius MD et al: Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci U S A. 100(1):253-8, 2003
                          18. Raichle ME et al: A default mode of brain function. Proc Natl Acad Sci U S A. 98(2):676-82, 2001