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Degenerated Leiomyoma
Marc S. Tubay, MD
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Clinical Issues

        TERMINOLOGY

        • Synonyms

          • Degenerated fibroid
          • Degenerated fibroleiomyoma
          • Degenerated myoma
        • Definitions

          • Degeneration of benign myometrial smooth muscle tumor

        IMAGING

        • General Features

          • Radiographic Findings

            • CT Findings

              • MR Findings

                • Ultrasonographic Findings

                  • Angiographic Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Han SC et al: Degeneration of leiomyoma in patients referred for uterine fibroid embolization: incidence, imaging features and clinical characteristics. Yonsei Med J. 54(1):215-9, 2013
                                      2. Deshmukh SP et al: Role of MR imaging of uterine leiomyomas before and after embolization. Radiographics. 32(6):E251-81, 2012
                                      3. Lamarca M et al: Leiomyomatosis peritonealis disseminata with malignant degeneration. A case report. Eur J Gynaecol Oncol. 32(6):702-4, 2011
                                      4. Kitajima K et al: Standardized uptake values of uterine leiomyoma with 18F-FDG PET/CT: variation with age, size, degeneration, and contrast enhancement on MRI. Ann Nucl Med. 22(6):505-12, 2008
                                      5. Fogata ML et al: Degenerating cystic uterine fibroid mimics an ovarian cyst in a pregnant patient. J Ultrasound Med. 25(5):671-4, 2006
                                      6. Ouyang DW et al: Obstetric complications of fibroids. Obstet Gynecol Clin North Am. 33(1):153-69, 2006
                                      7. Semelka R: Abdominal-Pelvic MRI. 2nd ed. Hoboken: Wiley. 1266-76, 2006
                                      8. Birchard KR et al: MRI of acute abdominal and pelvic pain in pregnant patients. AJR Am J Roentgenol. 184(2):452-8, 2005
                                      9. Pelage JP et al: Uterine fibroid vascularization and clinical relevance to uterine fibroid embolization. Radiographics. 25 Suppl 1:S99-117, 2005
                                      10. Low SC et al: A case of cystic leiomyoma mimicking an ovarian malignancy. Ann Acad Med Singapore. 33(3):371-4, 2004
                                      11. Bennett GL et al: Gynecologic causes of acute pelvic pain: spectrum of CT findings. Radiographics. 22(4):785-801, 2002
                                      12. Kamat NV et al: Ruptured degenerated uterine fibroid diagnosed by imaging. Obstet Gynecol. 98(5 Pt 2):961-3, 2001
                                      13. Coronado GD et al: Complications in pregnancy, labor, and delivery with uterine leiomyomas: a population-based study. Obstet Gynecol. 95(5):764-9, 2000
                                      14. Robboy SJ et al: Pathology and pathophysiology of uterine smooth-muscle tumors. Environ Health Perspect. 108 Suppl 5:779-84, 2000
                                      15. Murase E et al: Uterine leiomyomas: histopathologic features, MR imaging findings, differential diagnosis, and treatment. Radiographics. 19(5):1179-97, 1999
                                      16. Ueda H et al: Unusual appearances of uterine leiomyomas: MR imaging findings and their histopathologic backgrounds. Radiographics. 19 Spec No:S131-45, 1999
                                      17. Yarwood RL et al: Cystic degeneration of a uterine leiomyoma masquerading as a postmenopausal ovarian cyst. A case report. J Reprod Med. 44(7):649-52, 1999
                                      18. Cohen JR et al: Ultrasonic "honeycomb" appearance of uterine submucous fibroids undergoing cystic degeneration. J Clin Ultrasound. 23(5):293-6, 1995
                                      19. Callen P: Ultrasonography in Obstetrics and Gynecology. 3rd ed. Philadelphia: Saunders. 603-8, 1994
                                      20. Casillas J et al: CT appearance of uterine leiomyomas. Radiographics. 10(6):999-1007, 1990
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Clinical Issues

                                            TERMINOLOGY

                                            • Synonyms

                                              • Degenerated fibroid
                                              • Degenerated fibroleiomyoma
                                              • Degenerated myoma
                                            • Definitions

                                              • Degeneration of benign myometrial smooth muscle tumor

                                            IMAGING

                                            • General Features

                                              • Radiographic Findings

                                                • CT Findings

                                                  • MR Findings

                                                    • Ultrasonographic Findings

                                                      • Angiographic Findings

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Gross Pathologic & Surgical Features

                                                              • Microscopic Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Han SC et al: Degeneration of leiomyoma in patients referred for uterine fibroid embolization: incidence, imaging features and clinical characteristics. Yonsei Med J. 54(1):215-9, 2013
                                                                          2. Deshmukh SP et al: Role of MR imaging of uterine leiomyomas before and after embolization. Radiographics. 32(6):E251-81, 2012
                                                                          3. Lamarca M et al: Leiomyomatosis peritonealis disseminata with malignant degeneration. A case report. Eur J Gynaecol Oncol. 32(6):702-4, 2011
                                                                          4. Kitajima K et al: Standardized uptake values of uterine leiomyoma with 18F-FDG PET/CT: variation with age, size, degeneration, and contrast enhancement on MRI. Ann Nucl Med. 22(6):505-12, 2008
                                                                          5. Fogata ML et al: Degenerating cystic uterine fibroid mimics an ovarian cyst in a pregnant patient. J Ultrasound Med. 25(5):671-4, 2006
                                                                          6. Ouyang DW et al: Obstetric complications of fibroids. Obstet Gynecol Clin North Am. 33(1):153-69, 2006
                                                                          7. Semelka R: Abdominal-Pelvic MRI. 2nd ed. Hoboken: Wiley. 1266-76, 2006
                                                                          8. Birchard KR et al: MRI of acute abdominal and pelvic pain in pregnant patients. AJR Am J Roentgenol. 184(2):452-8, 2005
                                                                          9. Pelage JP et al: Uterine fibroid vascularization and clinical relevance to uterine fibroid embolization. Radiographics. 25 Suppl 1:S99-117, 2005
                                                                          10. Low SC et al: A case of cystic leiomyoma mimicking an ovarian malignancy. Ann Acad Med Singapore. 33(3):371-4, 2004
                                                                          11. Bennett GL et al: Gynecologic causes of acute pelvic pain: spectrum of CT findings. Radiographics. 22(4):785-801, 2002
                                                                          12. Kamat NV et al: Ruptured degenerated uterine fibroid diagnosed by imaging. Obstet Gynecol. 98(5 Pt 2):961-3, 2001
                                                                          13. Coronado GD et al: Complications in pregnancy, labor, and delivery with uterine leiomyomas: a population-based study. Obstet Gynecol. 95(5):764-9, 2000
                                                                          14. Robboy SJ et al: Pathology and pathophysiology of uterine smooth-muscle tumors. Environ Health Perspect. 108 Suppl 5:779-84, 2000
                                                                          15. Murase E et al: Uterine leiomyomas: histopathologic features, MR imaging findings, differential diagnosis, and treatment. Radiographics. 19(5):1179-97, 1999
                                                                          16. Ueda H et al: Unusual appearances of uterine leiomyomas: MR imaging findings and their histopathologic backgrounds. Radiographics. 19 Spec No:S131-45, 1999
                                                                          17. Yarwood RL et al: Cystic degeneration of a uterine leiomyoma masquerading as a postmenopausal ovarian cyst. A case report. J Reprod Med. 44(7):649-52, 1999
                                                                          18. Cohen JR et al: Ultrasonic "honeycomb" appearance of uterine submucous fibroids undergoing cystic degeneration. J Clin Ultrasound. 23(5):293-6, 1995
                                                                          19. Callen P: Ultrasonography in Obstetrics and Gynecology. 3rd ed. Philadelphia: Saunders. 603-8, 1994
                                                                          20. Casillas J et al: CT appearance of uterine leiomyomas. Radiographics. 10(6):999-1007, 1990