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Dermatofibrosarcoma Protuberans
Catherine C. Roberts, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Dermatofibrosarcoma protuberans (DFSP)
          • Synonyms

            • Progressive and recurring dermatofibroma
          • Definitions

            • Low-grade mesenchymal sarcoma of dermis and subcutis

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Angiographic Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    Selected References

                                    1. Basu S et al: Aggressive clinical course of dermatofibrosarcoma protuberans: 18F-FDG PET-CT predictive of tumor biology. J Nucl Med Technol. ePub, 2015
                                    2. Kuzel P et al: A clinicopathologic review of a case series of dermatofibrosarcoma protuberans with fibrosarcomatous differentiation. J Cutan Med Surg. 19(1):28-34, 2015
                                    3. Saiag P et al: Diagnosis and treatment of dermatofibrosarcoma protuberans. European consensus-based interdisciplinary guideline. Eur J Cancer. ePub, 2015
                                    4. Zhang L et al: Dermatofibrosarcoma Protuberans: Computed Tomography and Magnetic Resonance Imaging Findings. Medicine (Baltimore). 94(24):e1001, 2015
                                    5. Lee MH et al: Cyst-like solid tumors of the musculoskeletal system: an analysis of ultrasound findings. Skeletal Radiol. 39(10):981-6, 2010
                                    6. Weiss SW et al: Fibrohistiocytic tumors of intermediate malignancy. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier. 371-82, 2008
                                    7. Kransdorf MJ et al: Malignant fibrous and fibrohistiocytic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 257-60, 2006
                                    8. Weyers W et al: Fibrous, fibrohistiocytic and histiocytic tumours. In LeBolt PE et al: World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours. Lyon: IARC Press. 259-60, 2006
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Pathology

                                          • Clinical Issues

                                            TERMINOLOGY

                                            • Abbreviations

                                              • Dermatofibrosarcoma protuberans (DFSP)
                                            • Synonyms

                                              • Progressive and recurring dermatofibroma
                                            • Definitions

                                              • Low-grade mesenchymal sarcoma of dermis and subcutis

                                            IMAGING

                                            • General Features

                                              • Radiographic Findings

                                                • CT Findings

                                                  • MR Findings

                                                    • Angiographic Findings

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • General Features

                                                          • Gross Pathologic & Surgical Features

                                                            • Microscopic Features

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      Selected References

                                                                      1. Basu S et al: Aggressive clinical course of dermatofibrosarcoma protuberans: 18F-FDG PET-CT predictive of tumor biology. J Nucl Med Technol. ePub, 2015
                                                                      2. Kuzel P et al: A clinicopathologic review of a case series of dermatofibrosarcoma protuberans with fibrosarcomatous differentiation. J Cutan Med Surg. 19(1):28-34, 2015
                                                                      3. Saiag P et al: Diagnosis and treatment of dermatofibrosarcoma protuberans. European consensus-based interdisciplinary guideline. Eur J Cancer. ePub, 2015
                                                                      4. Zhang L et al: Dermatofibrosarcoma Protuberans: Computed Tomography and Magnetic Resonance Imaging Findings. Medicine (Baltimore). 94(24):e1001, 2015
                                                                      5. Lee MH et al: Cyst-like solid tumors of the musculoskeletal system: an analysis of ultrasound findings. Skeletal Radiol. 39(10):981-6, 2010
                                                                      6. Weiss SW et al: Fibrohistiocytic tumors of intermediate malignancy. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier. 371-82, 2008
                                                                      7. Kransdorf MJ et al: Malignant fibrous and fibrohistiocytic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 257-60, 2006
                                                                      8. Weyers W et al: Fibrous, fibrohistiocytic and histiocytic tumours. In LeBolt PE et al: World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours. Lyon: IARC Press. 259-60, 2006