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Dermatomyositis
Christopher G. Anton, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        TERMINOLOGY

        • Definitions

          • Juvenile dermatomyositis (JDM): Diffuse, nonsuppurative inflammation of striated muscle, subcutaneous fat, & skin
          • Most common (85%) of juvenile idiopathic inflammatory myopathies

        IMAGING

        • General Features

          • Radiographic Findings

            • Fluoroscopic Findings

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Zadig P et al: Whole-body magnetic resonance imaging in children - how and why? A systematic review. Pediatr Radiol. 51(1):14-24, 2021
                                          2. Sag E et al: Clinical features, muscle biopsy scores, myositis specific antibody profiles and outcome in juvenile dermatomyositis. Semin Arthritis Rheum. 51(1):95-100, 2020
                                          3. Sudoł-Szopińska I et al: Imaging in dermatomyositis in adults and children. J Ultrason. 20(80):e36-42, 2020
                                          4. Pachman LM et al: Advances in juvenile dermatomyositis: myositis specific antibodies aid in understanding disease heterogeneity. J Pediatr. 195:16-27, 2018
                                          5. Bellutti Enders F et al: Consensus-based recommendations for the management of juvenile dermatomyositis. Ann Rheum Dis. 76(2):329-40, 2017
                                          6. Damasio MB et al: Whole-body MRI: non-oncological applications in paediatrics. Radiol Med. 121(5): 454-61, 2016
                                          7. Deakin CT et al: Muscle biopsy findings in combination with myositis-specific autoantibodies aid prediction of outcomes in juvenile dermatomyositis. Arthritis Rheumatol. 68(11):2806-16, 2016
                                          8. Richardson AE et al: Respiratory complications of the rheumatological diseases in childhood. Arch Dis Child. 101(8):752-8, 2016
                                          9. Sun C et al: Juvenile dermatomyositis: a 20-year retrospective analysis of treatment and clinical outcomes. Pediatr Neonatol. 56(1):31-9, 2015
                                          10. Ernste FC et al: Recent advances in juvenile idiopathic inflammatory myopathies. Curr Opin Rheumatol. 26(6):671-8, 2014
                                          11. Lilleby V et al: Severe macrophage activation syndrome and central nervous system involvement in juvenile dermatomyositis. Scand J Rheumatol. 43(2):171-3, 2014
                                          12. Ladd PE et al: Juvenile dermatomyositis: correlation of MRI at presentation with clinical outcome. AJR Am J Roentgenol. 197(1):W153-8, 2011
                                          13. Castro TC et al: Detection of multifocal osteonecrosis in an adolescent with dermatomyositis using whole-body MRI. Pediatr Radiol. 40(9):1566-8, 2010
                                          14. Mammen AL: Dermatomyositis and polymyositis: clinical presentation, autoantibodies, and pathogenesis. Ann N Y Acad Sci. 1184:134-53, 2010
                                          15. Sanner H et al: Long-term muscular outcome and predisposing and prognostic factors in juvenile dermatomyositis: a case-control study. Arthritis Care Res (Hoboken). 62(8):1103-11, 2010
                                          16. Selva-O'Callaghan A et al: Conventional cancer screening versus PET/CT in dermatomyositis/polymyositis. Am J Med. 123(6):558-62, 2010
                                          17. Tzaribachev N et al: Whole-body MRI: a helpful diagnostic tool for juvenile dermatomyositis case report and review of the literature. Rheumatol Int. 29(12):1511-4, 2009
                                          18. Weber MA: Ultrasound in the inflammatory myopathies. Ann N Y Acad Sci. 1154:159-70, 2009
                                          19. Moulton SJ et al: Eosinophilic fasciitis: spectrum of MRI findings. AJR Am J Roentgenol. 184(3):975-8, 2005
                                          20. Danko K et al: Long-term survival of patients with idiopathic inflammatory myopathies according to clinical features: a longitudinal study of 162 cases. Medicine (Baltimore). 83(1):35-42, 2004
                                          Related Anatomy
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Definitions

                                                  • Juvenile dermatomyositis (JDM): Diffuse, nonsuppurative inflammation of striated muscle, subcutaneous fat, & skin
                                                  • Most common (85%) of juvenile idiopathic inflammatory myopathies

                                                IMAGING

                                                • General Features

                                                  • Radiographic Findings

                                                    • Fluoroscopic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Zadig P et al: Whole-body magnetic resonance imaging in children - how and why? A systematic review. Pediatr Radiol. 51(1):14-24, 2021
                                                                                  2. Sag E et al: Clinical features, muscle biopsy scores, myositis specific antibody profiles and outcome in juvenile dermatomyositis. Semin Arthritis Rheum. 51(1):95-100, 2020
                                                                                  3. Sudoł-Szopińska I et al: Imaging in dermatomyositis in adults and children. J Ultrason. 20(80):e36-42, 2020
                                                                                  4. Pachman LM et al: Advances in juvenile dermatomyositis: myositis specific antibodies aid in understanding disease heterogeneity. J Pediatr. 195:16-27, 2018
                                                                                  5. Bellutti Enders F et al: Consensus-based recommendations for the management of juvenile dermatomyositis. Ann Rheum Dis. 76(2):329-40, 2017
                                                                                  6. Damasio MB et al: Whole-body MRI: non-oncological applications in paediatrics. Radiol Med. 121(5): 454-61, 2016
                                                                                  7. Deakin CT et al: Muscle biopsy findings in combination with myositis-specific autoantibodies aid prediction of outcomes in juvenile dermatomyositis. Arthritis Rheumatol. 68(11):2806-16, 2016
                                                                                  8. Richardson AE et al: Respiratory complications of the rheumatological diseases in childhood. Arch Dis Child. 101(8):752-8, 2016
                                                                                  9. Sun C et al: Juvenile dermatomyositis: a 20-year retrospective analysis of treatment and clinical outcomes. Pediatr Neonatol. 56(1):31-9, 2015
                                                                                  10. Ernste FC et al: Recent advances in juvenile idiopathic inflammatory myopathies. Curr Opin Rheumatol. 26(6):671-8, 2014
                                                                                  11. Lilleby V et al: Severe macrophage activation syndrome and central nervous system involvement in juvenile dermatomyositis. Scand J Rheumatol. 43(2):171-3, 2014
                                                                                  12. Ladd PE et al: Juvenile dermatomyositis: correlation of MRI at presentation with clinical outcome. AJR Am J Roentgenol. 197(1):W153-8, 2011
                                                                                  13. Castro TC et al: Detection of multifocal osteonecrosis in an adolescent with dermatomyositis using whole-body MRI. Pediatr Radiol. 40(9):1566-8, 2010
                                                                                  14. Mammen AL: Dermatomyositis and polymyositis: clinical presentation, autoantibodies, and pathogenesis. Ann N Y Acad Sci. 1184:134-53, 2010
                                                                                  15. Sanner H et al: Long-term muscular outcome and predisposing and prognostic factors in juvenile dermatomyositis: a case-control study. Arthritis Care Res (Hoboken). 62(8):1103-11, 2010
                                                                                  16. Selva-O'Callaghan A et al: Conventional cancer screening versus PET/CT in dermatomyositis/polymyositis. Am J Med. 123(6):558-62, 2010
                                                                                  17. Tzaribachev N et al: Whole-body MRI: a helpful diagnostic tool for juvenile dermatomyositis case report and review of the literature. Rheumatol Int. 29(12):1511-4, 2009
                                                                                  18. Weber MA: Ultrasound in the inflammatory myopathies. Ann N Y Acad Sci. 1154:159-70, 2009
                                                                                  19. Moulton SJ et al: Eosinophilic fasciitis: spectrum of MRI findings. AJR Am J Roentgenol. 184(3):975-8, 2005
                                                                                  20. Danko K et al: Long-term survival of patients with idiopathic inflammatory myopathies according to clinical features: a longitudinal study of 162 cases. Medicine (Baltimore). 83(1):35-42, 2004