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Dermoid Cyst
Kevin R. Moore, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Dermoid tumor, "dermoid"
              • Definitions

                • Benign spinal mass
                • Composed of cells that embryologically comprise skin and its appendages (hair follicles, sweat glands, and sebaceous glands)

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Ultrasonographic Findings

                        • Nonvascular Interventions

                          • Imaging Recommendations

                            DIFFERENTIAL DIAGNOSIS

                              PATHOLOGY

                              • General Features

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            DIAGNOSTIC CHECKLIST

                                            • Consider

                                              • Image Interpretation Pearls

                                                Selected References

                                                1. Suocheng G et al: A review on five cases of intramedullary dermoid cyst. Childs Nerv Syst. 30(4):659-64, 2014
                                                2. Lee B et al: Congenital dermal sinus with an infected dermoid cyst in the cervico-thoracic spinal cord. Pediatr Neurosurg. 49(2):89-92, 2013
                                                3. Sahoo RK et al: Congenital dermal sinus in mid-dorsal spine with large intramedullary dermoid cyst in an 18-months-old child. J Pediatr Neurosci. 8(3):201-3, 2013
                                                4. Zhang Y et al: Magnetic resonance imaging of ruptured spinal dermoid tumors with spread of fatty droplets in the central spinal canal and/or spinal subarachnoidal space. J Neuroimaging. 23(1):71-4, 2013
                                                5. De Maio PN et al: AIRP best cases in radiologic-pathologic correlation: Spinal conus dermoid cyst with lipid dissemination. Radiographics. 32(4):1215-21, 2012
                                                6. van Aalst J et al: Intraspinal dermoid and epidermoid tumors: report of 18 cases and reappraisal of the literature. Pediatr Neurosurg. 45(4):281-90, 2009
                                                7. Danzer E et al: Intradural inclusion cysts following in utero closure of myelomeningocele: clinical implications and follow-up findings. J Neurosurg Pediatr. 2(6):406-13, 2008
                                                8. Ramos E et al: Congenital dermoid tumor in a child at initial myelomeningocele closure: an etiological discussion. J Neurosurg Pediatr. 2(6):414-5, 2008
                                                9. Kasliwal MK et al: Symptomatic central canal rupture heralding the presence of an asymptomatic conus dermoid. J Neurooncol. 84(1):39-40, 2007
                                                10. Kukreja K et al: Differentiation between pediatric spinal arachnoid and epidermoid-dermoid cysts: is diffusion-weighted MRI useful? Pediatr Radiol. 37(6):556-60, 2007
                                                11. Muthukumar N et al: Intramedullary dermoid in a low lying conus tethered by a fatty filum - embryological implications. Acta Neurochir (Wien). 149(11):1173-5, 2007
                                                12. Coppens JR et al: Presumed rupture of a conus medullaris dermoid cyst with cervical intramedullary fat and lipomatous infiltration of the cauda equina. Case illustration. J Neurosurg Spine. 5(2):178, 2006
                                                13. Terai T et al: Adult onset tethered cord syndrome associated with intradural dermoid cyst. A case report. Spinal Cord. 44(4):260-2, 2006
                                                14. Najjar MW et al: Dorsal intramedullary dermoids. Neurosurg Rev. 28(4):320-5, 2005
                                                15. Goyal A et al: Spontaneous rupture of spinal dermoid cyst with disseminated lipid droplets in central canal and ventricles. J Neurosurg Sci. 48(2):63-5, 2004
                                                16. Ziv ET et al: Iatrogenic intraspinal epidermoid tumor: two cases and a review of the literature. Spine. 29(1):E15-8, 2004
                                                17. Bretz A et al: Intraspinal epidermoid cyst successfully treated with radiotherapy: case report. Neurosurgery. 53(6):1429-31; discussion 1431-2, 2003
                                                18. Ferrara P et al: Intramedullary epidermoid cyst presenting with abnormal urological manifestations. Spinal Cord. 41(11):645-8, 2003
                                                19. Amato VG et al: Intramedullary epidermoid cyst: preoperative diagnosis and surgical management after MRI introduction. Case report and updating of the literature. J Neurosurg Sci. 46(3-4):122-6, 2002
                                                20. Graham D et al: Greenfield's Neuropathology. 7th ed. London: Arnold. 964-966, 2002
                                                21. Scarrow AM et al: Epidermoid cyst of the thoracic spine: case history. Clin Neurol Neurosurg. 103(4):220-2, 2001
                                                22. Kikuchi K et al: The utility of diffusion-weighted imaging with navigator-echo technique for the diagnosis of spinal epidermoid cysts. AJNR Am J Neuroradiol. 21(6):1164-6, 2000
                                                23. Potgieter S et al: Epidermoid tumours associated with lumbar punctures performed in early neonatal life. Dev Med Child Neurol. 40(4):266-9, 1998
                                                24. Machida T et al: Acquired epidermoid tumour in the thoracic spinal canal. Neuroradiology. 35(4):316-8, 1993
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Pathology

                                                        • Clinical Issues

                                                          • Diagnostic Checklist

                                                            TERMINOLOGY

                                                            • Synonyms

                                                              • Dermoid tumor, "dermoid"
                                                            • Definitions

                                                              • Benign spinal mass
                                                              • Composed of cells that embryologically comprise skin and its appendages (hair follicles, sweat glands, and sebaceous glands)

                                                            IMAGING

                                                            • General Features

                                                              • Radiographic Findings

                                                                • CT Findings

                                                                  • MR Findings

                                                                    • Ultrasonographic Findings

                                                                      • Nonvascular Interventions

                                                                        • Imaging Recommendations

                                                                          DIFFERENTIAL DIAGNOSIS

                                                                            PATHOLOGY

                                                                            • General Features

                                                                              • Gross Pathologic & Surgical Features

                                                                                • Microscopic Features

                                                                                  CLINICAL ISSUES

                                                                                  • Presentation

                                                                                    • Demographics

                                                                                      • Natural History & Prognosis

                                                                                        • Treatment

                                                                                          DIAGNOSTIC CHECKLIST

                                                                                          • Consider

                                                                                            • Image Interpretation Pearls

                                                                                              Selected References

                                                                                              1. Suocheng G et al: A review on five cases of intramedullary dermoid cyst. Childs Nerv Syst. 30(4):659-64, 2014
                                                                                              2. Lee B et al: Congenital dermal sinus with an infected dermoid cyst in the cervico-thoracic spinal cord. Pediatr Neurosurg. 49(2):89-92, 2013
                                                                                              3. Sahoo RK et al: Congenital dermal sinus in mid-dorsal spine with large intramedullary dermoid cyst in an 18-months-old child. J Pediatr Neurosci. 8(3):201-3, 2013
                                                                                              4. Zhang Y et al: Magnetic resonance imaging of ruptured spinal dermoid tumors with spread of fatty droplets in the central spinal canal and/or spinal subarachnoidal space. J Neuroimaging. 23(1):71-4, 2013
                                                                                              5. De Maio PN et al: AIRP best cases in radiologic-pathologic correlation: Spinal conus dermoid cyst with lipid dissemination. Radiographics. 32(4):1215-21, 2012
                                                                                              6. van Aalst J et al: Intraspinal dermoid and epidermoid tumors: report of 18 cases and reappraisal of the literature. Pediatr Neurosurg. 45(4):281-90, 2009
                                                                                              7. Danzer E et al: Intradural inclusion cysts following in utero closure of myelomeningocele: clinical implications and follow-up findings. J Neurosurg Pediatr. 2(6):406-13, 2008
                                                                                              8. Ramos E et al: Congenital dermoid tumor in a child at initial myelomeningocele closure: an etiological discussion. J Neurosurg Pediatr. 2(6):414-5, 2008
                                                                                              9. Kasliwal MK et al: Symptomatic central canal rupture heralding the presence of an asymptomatic conus dermoid. J Neurooncol. 84(1):39-40, 2007
                                                                                              10. Kukreja K et al: Differentiation between pediatric spinal arachnoid and epidermoid-dermoid cysts: is diffusion-weighted MRI useful? Pediatr Radiol. 37(6):556-60, 2007
                                                                                              11. Muthukumar N et al: Intramedullary dermoid in a low lying conus tethered by a fatty filum - embryological implications. Acta Neurochir (Wien). 149(11):1173-5, 2007
                                                                                              12. Coppens JR et al: Presumed rupture of a conus medullaris dermoid cyst with cervical intramedullary fat and lipomatous infiltration of the cauda equina. Case illustration. J Neurosurg Spine. 5(2):178, 2006
                                                                                              13. Terai T et al: Adult onset tethered cord syndrome associated with intradural dermoid cyst. A case report. Spinal Cord. 44(4):260-2, 2006
                                                                                              14. Najjar MW et al: Dorsal intramedullary dermoids. Neurosurg Rev. 28(4):320-5, 2005
                                                                                              15. Goyal A et al: Spontaneous rupture of spinal dermoid cyst with disseminated lipid droplets in central canal and ventricles. J Neurosurg Sci. 48(2):63-5, 2004
                                                                                              16. Ziv ET et al: Iatrogenic intraspinal epidermoid tumor: two cases and a review of the literature. Spine. 29(1):E15-8, 2004
                                                                                              17. Bretz A et al: Intraspinal epidermoid cyst successfully treated with radiotherapy: case report. Neurosurgery. 53(6):1429-31; discussion 1431-2, 2003
                                                                                              18. Ferrara P et al: Intramedullary epidermoid cyst presenting with abnormal urological manifestations. Spinal Cord. 41(11):645-8, 2003
                                                                                              19. Amato VG et al: Intramedullary epidermoid cyst: preoperative diagnosis and surgical management after MRI introduction. Case report and updating of the literature. J Neurosurg Sci. 46(3-4):122-6, 2002
                                                                                              20. Graham D et al: Greenfield's Neuropathology. 7th ed. London: Arnold. 964-966, 2002
                                                                                              21. Scarrow AM et al: Epidermoid cyst of the thoracic spine: case history. Clin Neurol Neurosurg. 103(4):220-2, 2001
                                                                                              22. Kikuchi K et al: The utility of diffusion-weighted imaging with navigator-echo technique for the diagnosis of spinal epidermoid cysts. AJNR Am J Neuroradiol. 21(6):1164-6, 2000
                                                                                              23. Potgieter S et al: Epidermoid tumours associated with lumbar punctures performed in early neonatal life. Dev Med Child Neurol. 40(4):266-9, 1998
                                                                                              24. Machida T et al: Acquired epidermoid tumour in the thoracic spinal canal. Neuroradiology. 35(4):316-8, 1993