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Desmoplastic Fibroblastoma
Eric Walker, MD, MHA, FACR, FACHE; Catherine C. Roberts, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Collagenous fibroma
          • Definitions

            • Benign paucicellular soft tissue tumor with abundant collagenous or myxocollagenous matrix

          IMAGING

          • General Features

            • CT Findings

              • Ultrasonographic Findings

                • Nuclear Medicine Findings

                  • Radiographic Findings

                    • MR Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        Selected References

                                        1. Nakayama S et al: An update on clinicopathological, imaging and genetic features of desmoplastic fibroblastoma (collagenous fibroma). In Vivo. 35(1):69-73, 2021
                                        2. Onghena L et al: Intramuscular desmoplastic fibroblastoma: a case report of extreme rarities in extremities. J Surg Case Rep. 2021(10):rjab461, 2021
                                        3. Kresse ME et al: Desmoplastic fibroblastoma: an uncommon tumor with a relatively characteristic MRI appearance. AJR Am J Roentgenol. 215(1):178-83, 2020
                                        4. Miettinen M et al: Desmoplastic fibroblastoma. In Fletcher CDM et al: WHO Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 69-70, 2020
                                        5. Matsunobu T et al: Desmoplastic fibroblastoma invading the humerus. Case Rep Orthop. 2020:9780263, 2020
                                        6. Yao JM et al: [Desmoplastic fibroblastoma: a clinicopathologic analysis of 7 cases.] Zhonghua Bing Li Xue Za Zhi. 46(4):223-7, 2017
                                        7. Kransdorf MJ et al: Fibrous and fibrohistiocytic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 249-51, 2014
                                        8. Bonardi M et al: US and MRI appearance of a collagenous fibroma (desmoplastic fibroblastoma) of the shoulder. J Ultrasound. 17(1):53-6, 2014
                                        9. Yamamoto A et al: Three cases of collagenous fibroma with rim enhancement on postcontrast T1-weighted images with fat suppression. Skeletal Radiol. 42(1):141-6, 2013
                                        10. Weiss SW et al: Benign fibroblastic/myofibroblastic proliferations. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 219-20, 2008
                                        11. Sakamoto A et al: Desmoplastic fibroblastoma (collagenous fibroma) with a specific breakpoint of 11q12. Histopathology. 51(6):859-60, 2007
                                        12. Walker KR et al: Collagenous fibroma (desmoplastic fibroblastoma) of the shoulder. AJR Am J Roentgenol. 183(6):1766, 2004
                                        13. Miettinen M et al: Desmoplastic fibroblastoma. In Fletcher CDM et al: WHO Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 67, 2002
                                        14. Shuto R et al: CT and MR imaging of desmoplastic fibroblastoma. Eur Radiol. 12(10):2474-6, 2002
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Pathology

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Synonyms

                                                  • Collagenous fibroma
                                                • Definitions

                                                  • Benign paucicellular soft tissue tumor with abundant collagenous or myxocollagenous matrix

                                                IMAGING

                                                • General Features

                                                  • CT Findings

                                                    • Ultrasonographic Findings

                                                      • Nuclear Medicine Findings

                                                        • Radiographic Findings

                                                          • MR Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              Selected References

                                                                              1. Nakayama S et al: An update on clinicopathological, imaging and genetic features of desmoplastic fibroblastoma (collagenous fibroma). In Vivo. 35(1):69-73, 2021
                                                                              2. Onghena L et al: Intramuscular desmoplastic fibroblastoma: a case report of extreme rarities in extremities. J Surg Case Rep. 2021(10):rjab461, 2021
                                                                              3. Kresse ME et al: Desmoplastic fibroblastoma: an uncommon tumor with a relatively characteristic MRI appearance. AJR Am J Roentgenol. 215(1):178-83, 2020
                                                                              4. Miettinen M et al: Desmoplastic fibroblastoma. In Fletcher CDM et al: WHO Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 69-70, 2020
                                                                              5. Matsunobu T et al: Desmoplastic fibroblastoma invading the humerus. Case Rep Orthop. 2020:9780263, 2020
                                                                              6. Yao JM et al: [Desmoplastic fibroblastoma: a clinicopathologic analysis of 7 cases.] Zhonghua Bing Li Xue Za Zhi. 46(4):223-7, 2017
                                                                              7. Kransdorf MJ et al: Fibrous and fibrohistiocytic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 249-51, 2014
                                                                              8. Bonardi M et al: US and MRI appearance of a collagenous fibroma (desmoplastic fibroblastoma) of the shoulder. J Ultrasound. 17(1):53-6, 2014
                                                                              9. Yamamoto A et al: Three cases of collagenous fibroma with rim enhancement on postcontrast T1-weighted images with fat suppression. Skeletal Radiol. 42(1):141-6, 2013
                                                                              10. Weiss SW et al: Benign fibroblastic/myofibroblastic proliferations. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 219-20, 2008
                                                                              11. Sakamoto A et al: Desmoplastic fibroblastoma (collagenous fibroma) with a specific breakpoint of 11q12. Histopathology. 51(6):859-60, 2007
                                                                              12. Walker KR et al: Collagenous fibroma (desmoplastic fibroblastoma) of the shoulder. AJR Am J Roentgenol. 183(6):1766, 2004
                                                                              13. Miettinen M et al: Desmoplastic fibroblastoma. In Fletcher CDM et al: WHO Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 67, 2002
                                                                              14. Shuto R et al: CT and MR imaging of desmoplastic fibroblastoma. Eur Radiol. 12(10):2474-6, 2002