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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
- Lymphocytic mastopathy
- Diabetic fibrous breast disease (DFBD)
- Diabetic fibrous mastopathy
- Sclerosing lymphocytic lobulitis
Definitions
- Periductal, perilobular, and perivascular lymphocytic infiltrate associated with dense interlobular stroma
- Occurs primarily in women with longstanding insulin-dependent (type 1) diabetes
- Periductal, perilobular, and perivascular lymphocytic infiltrate associated with dense interlobular stroma
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
Image-Guided Biopsy
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
- Agochukwu NB and Wong L. Diabetic mastopathy: A systematic review of surgical management of a rare breast disease. Ann Plast Surg. 78(4):471-5, 2017
- Kim J et al. Diabetic mastopathy: imaging features and the role of image-guided biopsy in its diagnosis. Ultrasonography. 35(2):140-7, 2016
- Chen LY et al. Lymphocyte subsets contribute to the degree of lobulitis and ductitis in sclerosing lymphocytic lobulitis of the breast. J Clin Pathol. 69(6):527-32, 2016
- Moschetta M et al. Diabetic mastopathy: a diagnostic challenge in breast sonography. J Clin Ultrasound. 43(2):113-7, 2015
- Suvannarerg V et al: Clinical, mammographic, and ultrasonographic characteristics of diabetic mastopathy: A case series. Clin Imaging. 53:204-209, 2018
- Dorokhova O et al: Diabetic mastopathy, a clinicopathological correlation of 34 cases. Pathol Int. 62(10):660-4, 2012
- Thorncroft K et al: The diagnosis and management of diabetic mastopathy. Breast J. 13(6):607-13, 2007
- Goel NB et al: Fibrous lesions of the breast: imaging-pathologic correlation. Radiographics. 25(6):1547-59, 2005
- Wong KT et al: Ultrasound and MR imaging of diabetic mastopathy. Clin Radiol. 57(8):730-5, 2002
- Weinstein SP et al: Diabetic mastopathy in men: imaging findings in two patients. Radiology. 219(3):797-9, 2001
- Ely KA et al: Diabetic mastopathy. A clinicopathologic review. Am J Clin Pathol. 113(4):541-5, 2000
- Bayer U et al: Bilateral, tumorlike diabetic mastopathy-progression and regression of the disease during 5-year follow up. Eur J Radiol. 26(3):248-53, 1998
- Hunfeld KP et al: Lymphocytic mastitis and fibrosis of the breast in long-standing insulin-dependent diabetics. A histopathologic study on diabetic mastopathy and report of ten cases. Gen Diagn Pathol. 143(1):49-58, 1997
- Lee AH et al: Sclerosing lymphocytic lobulitis in the male breast. J Clin Pathol. 49(7):609-11, 1996
- Logan WW et al: Diabetic fibrous breast disease. Radiology. 172(3):667-70, 1989
- Soler NG et al: Fibrous disease of the breast, thyroiditis, and cheiroarthropathy in type I diabetes mellitus. Lancet. 1(8370):193-5, 1984
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
- Lymphocytic mastopathy
- Diabetic fibrous breast disease (DFBD)
- Diabetic fibrous mastopathy
- Sclerosing lymphocytic lobulitis
Definitions
- Periductal, perilobular, and perivascular lymphocytic infiltrate associated with dense interlobular stroma
- Occurs primarily in women with longstanding insulin-dependent (type 1) diabetes
- Periductal, perilobular, and perivascular lymphocytic infiltrate associated with dense interlobular stroma
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
Image-Guided Biopsy
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
- Agochukwu NB and Wong L. Diabetic mastopathy: A systematic review of surgical management of a rare breast disease. Ann Plast Surg. 78(4):471-5, 2017
- Kim J et al. Diabetic mastopathy: imaging features and the role of image-guided biopsy in its diagnosis. Ultrasonography. 35(2):140-7, 2016
- Chen LY et al. Lymphocyte subsets contribute to the degree of lobulitis and ductitis in sclerosing lymphocytic lobulitis of the breast. J Clin Pathol. 69(6):527-32, 2016
- Moschetta M et al. Diabetic mastopathy: a diagnostic challenge in breast sonography. J Clin Ultrasound. 43(2):113-7, 2015
- Suvannarerg V et al: Clinical, mammographic, and ultrasonographic characteristics of diabetic mastopathy: A case series. Clin Imaging. 53:204-209, 2018
- Dorokhova O et al: Diabetic mastopathy, a clinicopathological correlation of 34 cases. Pathol Int. 62(10):660-4, 2012
- Thorncroft K et al: The diagnosis and management of diabetic mastopathy. Breast J. 13(6):607-13, 2007
- Goel NB et al: Fibrous lesions of the breast: imaging-pathologic correlation. Radiographics. 25(6):1547-59, 2005
- Wong KT et al: Ultrasound and MR imaging of diabetic mastopathy. Clin Radiol. 57(8):730-5, 2002
- Weinstein SP et al: Diabetic mastopathy in men: imaging findings in two patients. Radiology. 219(3):797-9, 2001
- Ely KA et al: Diabetic mastopathy. A clinicopathologic review. Am J Clin Pathol. 113(4):541-5, 2000
- Bayer U et al: Bilateral, tumorlike diabetic mastopathy-progression and regression of the disease during 5-year follow up. Eur J Radiol. 26(3):248-53, 1998
- Hunfeld KP et al: Lymphocytic mastitis and fibrosis of the breast in long-standing insulin-dependent diabetics. A histopathologic study on diabetic mastopathy and report of ten cases. Gen Diagn Pathol. 143(1):49-58, 1997
- Lee AH et al: Sclerosing lymphocytic lobulitis in the male breast. J Clin Pathol. 49(7):609-11, 1996
- Logan WW et al: Diabetic fibrous breast disease. Radiology. 172(3):667-70, 1989
- Soler NG et al: Fibrous disease of the breast, thyroiditis, and cheiroarthropathy in type I diabetes mellitus. Lancet. 1(8370):193-5, 1984
