Unusual growth pattern of uterine smooth muscle proliferation, resulting in diffuse uterine enlargement
IMAGING
General Features
Imaging Recommendations
Ultrasonographic Findings
CT Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Konishi I: Diffuse leiomyomatosis: complete myomectomy for innumerable small nodules to achieve fertility sparing and childbearing. Surg J (N Y). 6(Suppl 1):S50-7, 2020
Thiry T et al: Diffuse abdominopelvic leiomyomatosis: CT and MR imaging findings with histopathological correlation. Diagn Interv Imaging. 95(1):105-8, 2014
Keskin G et al: Diffuse peritoneal leiomyomatosis. J Obstet Gynaecol. 33(5):535-6, 2013
Agarwal K et al: Diffuse leiomyomatosis of the uterus diagnosed during pregnancy with successful vaginal delivery. Indian J Pathol Microbiol. 55(4):585-6, 2012
Koh J et al: Uterine artery embolization (UAE) for diffuse leiomyomatosis of the uterus: clinical and imaging results. Eur J Radiol. 81(10):2726-9, 2012
Pai D et al: Diffuse uterine leiomyomatosis in a child. Pediatr Radiol. 42(1):124-8, 2012
Purohit R et al: A case of diffuse uterine leiomyomatosis who had two successful pregnancies after medical management. Fertil Steril. 95(7):2434, 2011
Ip PP et al: Uterine smooth muscle tumors other than the ordinary leiomyomas and leiomyosarcomas: a review of selected variants with emphasis on recent advances and unusual morphology that may cause concern for malignancy. Adv Anat Pathol. 17(2):91-112, 2010
Coskun A et al: A case with diffuse uterine leiomyomatosis and review of the literature. Clin Exp Obstet Gynecol. 35(3):227-30, 2008
Scheurig C et al: Uterine artery embolization in patients with symptomatic diffuse leiomyomatosis of the uterus. J Vasc Interv Radiol. 19(2 Pt 1):279-84, 2008
Cohen DT et al: Uterine smooth-muscle tumors with unusual growth patterns: imaging with pathologic correlation. AJR Am J Roentgenol. 188(1):246-55, 2007
Thomas EO et al: Diffuse uterine leiomyomatosis with uterine rupture and benign metastatic lesions of the bone. Obstet Gynecol. 109:528-30, 2007
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KEY FACTS
Terminology
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TERMINOLOGY
Definitions
Unusual growth pattern of uterine smooth muscle proliferation, resulting in diffuse uterine enlargement
IMAGING
General Features
Imaging Recommendations
Ultrasonographic Findings
CT Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Konishi I: Diffuse leiomyomatosis: complete myomectomy for innumerable small nodules to achieve fertility sparing and childbearing. Surg J (N Y). 6(Suppl 1):S50-7, 2020
Thiry T et al: Diffuse abdominopelvic leiomyomatosis: CT and MR imaging findings with histopathological correlation. Diagn Interv Imaging. 95(1):105-8, 2014
Keskin G et al: Diffuse peritoneal leiomyomatosis. J Obstet Gynaecol. 33(5):535-6, 2013
Agarwal K et al: Diffuse leiomyomatosis of the uterus diagnosed during pregnancy with successful vaginal delivery. Indian J Pathol Microbiol. 55(4):585-6, 2012
Koh J et al: Uterine artery embolization (UAE) for diffuse leiomyomatosis of the uterus: clinical and imaging results. Eur J Radiol. 81(10):2726-9, 2012
Pai D et al: Diffuse uterine leiomyomatosis in a child. Pediatr Radiol. 42(1):124-8, 2012
Purohit R et al: A case of diffuse uterine leiomyomatosis who had two successful pregnancies after medical management. Fertil Steril. 95(7):2434, 2011
Ip PP et al: Uterine smooth muscle tumors other than the ordinary leiomyomas and leiomyosarcomas: a review of selected variants with emphasis on recent advances and unusual morphology that may cause concern for malignancy. Adv Anat Pathol. 17(2):91-112, 2010
Coskun A et al: A case with diffuse uterine leiomyomatosis and review of the literature. Clin Exp Obstet Gynecol. 35(3):227-30, 2008
Scheurig C et al: Uterine artery embolization in patients with symptomatic diffuse leiomyomatosis of the uterus. J Vasc Interv Radiol. 19(2 Pt 1):279-84, 2008
Cohen DT et al: Uterine smooth-muscle tumors with unusual growth patterns: imaging with pathologic correlation. AJR Am J Roentgenol. 188(1):246-55, 2007
Thomas EO et al: Diffuse uterine leiomyomatosis with uterine rupture and benign metastatic lesions of the bone. Obstet Gynecol. 109:528-30, 2007
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