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Diffuse Leptomeningeal Glioneuronal Tumor
Miral D. Jhaveri, MD, MBA
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Diffuse leptomeningeal glioneuronal tumor (DLGT)
              • Synonyms

                • Primary diffuse leptomeningeal oligodendroglioma
                • Leptomeningeal oligodendrogliomatosis
                • Dysembryoplastic neuroepithelial tumor-like neoplasm
                • Disseminated oligodendroglial-like leptomeningeal tumor of childhood
              • Definitions

                • DLGT is rare primary glioneuronal neoplasm characterized by widespread leptomeningeal growth

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          Selected References

                                          1. Teoh S et al: Disseminated leptomeningeal tumour mimicking a subarachnoid haemorrhage. Neuroradiol J. 32(1):53-6, 2019
                                          2. D'Arco F et al: Differential diagnosis of posterior fossa tumours in children: new insights. Pediatr Radiol. 48(13):1955-63, 2018
                                          3. Demir MK et al: Magnetic resonance imaging findings of mixed neuronal-glial tumors with pathologic correlation: a review. Acta Neurol Belg. 118(3):379-86, 2018
                                          4. Wesseling P et al: WHO 2016 Classification of gliomas. Neuropathol Appl Neurobiol. 44(2):139-50, 2018
                                          5. Johnson DR et al: 2016 Updates to the WHO Brain Tumor Classification System: what the radiologist needs to know. Radiographics. 37(7):2164-80, 2017
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Diffuse leptomeningeal glioneuronal tumor (DLGT)
                                                      • Synonyms

                                                        • Primary diffuse leptomeningeal oligodendroglioma
                                                        • Leptomeningeal oligodendrogliomatosis
                                                        • Dysembryoplastic neuroepithelial tumor-like neoplasm
                                                        • Disseminated oligodendroglial-like leptomeningeal tumor of childhood
                                                      • Definitions

                                                        • DLGT is rare primary glioneuronal neoplasm characterized by widespread leptomeningeal growth

                                                      IMAGING

                                                      • General Features

                                                        • CT Findings

                                                          • MR Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Staging, Grading, & Classification

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  Selected References

                                                                                  1. Teoh S et al: Disseminated leptomeningeal tumour mimicking a subarachnoid haemorrhage. Neuroradiol J. 32(1):53-6, 2019
                                                                                  2. D'Arco F et al: Differential diagnosis of posterior fossa tumours in children: new insights. Pediatr Radiol. 48(13):1955-63, 2018
                                                                                  3. Demir MK et al: Magnetic resonance imaging findings of mixed neuronal-glial tumors with pathologic correlation: a review. Acta Neurol Belg. 118(3):379-86, 2018
                                                                                  4. Wesseling P et al: WHO 2016 Classification of gliomas. Neuropathol Appl Neurobiol. 44(2):139-50, 2018
                                                                                  5. Johnson DR et al: 2016 Updates to the WHO Brain Tumor Classification System: what the radiologist needs to know. Radiographics. 37(7):2164-80, 2017