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Musculoskeletal
Diagnosis
Non-Trauma
Metabolic Bone Disease
Osteoporosis
Disuse Osteoporosis
Disuse Osteoporosis
Donna G. Blankenbaker, MD, FACR; Cheryl A. Petersilge, MD, MBA
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Pathology

        • Clinical Issues

          Selected References

          1. Rolvien T et al: Disuse osteoporosis: clinical and mechanistic insights. Calcif Tissue Int. ePub, 2021
          2. Bettis T et al: Impact of muscle atrophy on bone metabolism and bone strength: implications for muscle-bone crosstalk with aging and disuse. Osteoporos Int. 29(8):1713-20, 2018
          3. Osipov B et al: Systemic bone loss after fracture. Clin Rev Bone Miner Metab. 16(4):116-30, 2018
          4. Coupaud S et al: Decreases in bone mineral density at cortical and trabecular sites in the tibia and femur during the first year of spinal cord injury. Bone. 74:69-75, 2015
          5. Ji Z et al: Elcatonin attenuates disuse osteoporosis after fracture fixation of tubular bone in rats. J Orthop Surg Res. 10:103, 2015
          6. Nardo L et al: Bone marrow changes related to disuse. Eur Radiol. 23(12):3422-31, 2013
          7. Lerebours C et al: A multiscale mechanobiological model of bone remodelling predicts site-specific bone loss in the femur during osteoporosis and mechanical disuse. Biomech Model Mechanobiol. 15(1):43-67, 2015
          8. Mabilleau G et al: Comparison between quantitative X-ray imaging, dual energy X-ray absorptiometry and microCT in the assessment of bone mineral density in disuse-induced bone loss. J Musculoskelet Neuronal Interact. 15(1):42-52, 2015
          9. Falcai MJ et al: The osteogenic effects of swimming, jumping, and vibration on the protection of bone quality from disuse bone loss. Scand J Med Sci Sports. 25(3):390-7, 2015
          10. Yagan R et al: Double cortical line in the acetabular roof: a sign of disuse osteoporosis. Radiology. 165(1):171-5, 1987
          11. Joyce JM et al: Disuse osteoporosis: mimic of neoplastic disease. Skeletal Radiol. 15(2):129-32, 1986
          12. Jones G: Radiological appearances of disuse osteoporosis. Clin Radiol. 20(4):345-53, 1969
          Related Anatomy
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          Related Differential Diagnoses
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          References
          Tables

          Tables

          KEY FACTS

          • Imaging

            • Top Differential Diagnoses

              • Pathology

                • Clinical Issues

                  Selected References

                  1. Rolvien T et al: Disuse osteoporosis: clinical and mechanistic insights. Calcif Tissue Int. ePub, 2021
                  2. Bettis T et al: Impact of muscle atrophy on bone metabolism and bone strength: implications for muscle-bone crosstalk with aging and disuse. Osteoporos Int. 29(8):1713-20, 2018
                  3. Osipov B et al: Systemic bone loss after fracture. Clin Rev Bone Miner Metab. 16(4):116-30, 2018
                  4. Coupaud S et al: Decreases in bone mineral density at cortical and trabecular sites in the tibia and femur during the first year of spinal cord injury. Bone. 74:69-75, 2015
                  5. Ji Z et al: Elcatonin attenuates disuse osteoporosis after fracture fixation of tubular bone in rats. J Orthop Surg Res. 10:103, 2015
                  6. Nardo L et al: Bone marrow changes related to disuse. Eur Radiol. 23(12):3422-31, 2013
                  7. Lerebours C et al: A multiscale mechanobiological model of bone remodelling predicts site-specific bone loss in the femur during osteoporosis and mechanical disuse. Biomech Model Mechanobiol. 15(1):43-67, 2015
                  8. Mabilleau G et al: Comparison between quantitative X-ray imaging, dual energy X-ray absorptiometry and microCT in the assessment of bone mineral density in disuse-induced bone loss. J Musculoskelet Neuronal Interact. 15(1):42-52, 2015
                  9. Falcai MJ et al: The osteogenic effects of swimming, jumping, and vibration on the protection of bone quality from disuse bone loss. Scand J Med Sci Sports. 25(3):390-7, 2015
                  10. Yagan R et al: Double cortical line in the acetabular roof: a sign of disuse osteoporosis. Radiology. 165(1):171-5, 1987
                  11. Joyce JM et al: Disuse osteoporosis: mimic of neoplastic disease. Skeletal Radiol. 15(2):129-32, 1986
                  12. Jones G: Radiological appearances of disuse osteoporosis. Clin Radiol. 20(4):345-53, 1969